CAS 3810-74-0: Streptomycinsulfat
Beschreibung:
Streptomycinsulfat ist ein Aminoglykosid-Antibiotikum, das aus dem Bakterium Streptomyces griseus gewonnen wird. Es wird hauptsächlich zur Behandlung verschiedener bakterieller Infektionen eingesetzt, insbesondere solcher, die durch Mycobacterium tuberculosis verursacht werden, was es in der Tuberkulosetherapie bedeutend macht. Die Verbindung zeichnet sich durch ihre Fähigkeit aus, die bakterielle Proteinsynthese zu hemmen, indem sie an die 30S-ribosomale Untereinheit bindet, was den Übersetzungsprozess stört. Streptomycinsulfat ist ein weißes bis leicht gelbes kristallines Pulver, das in Wasser löslich ist, was die Verabreichung durch Injektion erleichtert. Es hat eine chemische Formel, die seine komplexe Struktur widerspiegelt, einschließlich mehrerer Amino- und Hydroxylgruppen. Die Sulfatform verbessert seine Löslichkeit und Stabilität. Zu den häufigen Nebenwirkungen gehören Ototoxizität und Nephrotoxizität, was eine sorgfältige Überwachung während der Behandlung erforderlich macht. Streptomycinsulfat ist auch bemerkenswert für seine Rolle bei der Entwicklung von Antibiotikaresistenzen, was die Bedeutung eines umsichtiges Einsatzes in klinischen Umgebungen unterstreicht. Insgesamt bleibt es ein kritischer Wirkstoff im Arsenal gegen bestimmte bakterielle Infektionen, insbesondere im Kontext von multiresistenten Stämmen.
Formel:C21H39N7O12H2O4S
InChl:InChI=1S/C21H39N7O12.H2O4S/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;1-5(2,3)4/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);(H2,1,2,3,4)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;/m0./s1
InChI Key:InChIKey=CFCMMYICHMLDCC-RMIBZTJPSA-N
SMILES:S(=O)(=O)(O)O.O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(C=O)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3
Synonyme:- 1,1'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (1:1)
- 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (2:3)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N<sup>1</sup>,N<sup>3</sup>-bis(aminoiminomethyl)-, sulfate (2:3)
- Ag Streptomycin
- Agri-Strep
- Agrimycin 17
- Agrimycin sulfate
- Ambistryn
- Ambistryn S
- D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
- Weitere Synonyme anzeigen
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FOURTH INTERNATIONAL STANDARD FOR STREPTOMYCIN
CAS:FOURTH INTERNATIONAL STANDARD FOR STREPTOMYCINFormel:C42H84N14O36S3Molekulargewicht:1457.384Streptomycin Sulphate (STM)
CAS:Formel:(C21H39N7O12)2·3H2SO4Farbe und Form:White to off - white, Crystalline powder, Clear, Pale yellowMolekulargewicht:1457.38Streptomycin Sulfate
CAS:Streptomycins and their derivatives; salts thereof, nesFormel:(C21H39N7O12)2·3(H2SO4)Farbe und Form:White PowderMolekulargewicht:1162.53134Streptomycin sulfate
CAS:Streptomycin sulfate (Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.Formel:C21H39N7O12H2SO4Reinheit:99.39% - 99.86%Farbe und Form:White To Off-White PowderMolekulargewicht:728.68Streptomycin sulfate, Cell Culture Reagent
CAS:Inhibits initiation and causes misreading of rRNA in protein synthesis Streptomycin sulfate is used to study the mechanisms of streptomycin resistance. It is used to inhibit bacterial contamination in cell culture applications in association with penicillin. It is an antibiotic drug initially used for tuberculosis treatment. It inhibits protein synthesis by binding to 30S ribosomal subunit, which induces the misreading of the genetic code. It is involved in the initiation of translation of DNA, thereby results in death for a susceptible bacterium. Further, it controls bacterial and fungal diseases of certain fruit, vegetables, seed, ornamental crops and algae in ornamental ponds and aquaria This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formel:C42H84N14O36S3Molekulargewicht:1457.38Streptomycin sulfate
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formel:C42H84N14O36S3Farbe und Form:White to off-white, PowderMolekulargewicht:1457.38Streptomycin Sulfate
CAS:Formel:C21H39N7O12H2SO4Reinheit:>95.0%(T)(N)Farbe und Form:White to Light yellow powder to crystalMolekulargewicht:728.69Streptomycin sulfate
CAS:Inhibitor of protein synthesis; aminoglycosideFormel:(C21H39N7O12)2•(H2SO4)3Reinheit:Min. 720 Iu/MgFarbe und Form:White Off-White PowderMolekulargewicht:1,457.39 g/molStreptomycin sulfate
CAS:Kontrolliertes ProduktFormel:C21H39N7O12H2O4SFarbe und Form:NeatMolekulargewicht:1457.38Streptomycin sulfate salt
CAS:4x25kgFormel:C21H39N7O12·5H2SO4Reinheit:≥ 720IU/mg (dry basis)Farbe und Form:White to off-white powderMolekulargewicht:728.69Streptomycin Sulfate [for Protein Research]
CAS:Formel:C21H39N7O12H2SO4Reinheit:>95.0%(N)Farbe und Form:White to Light yellow powder to crystalMolekulargewicht:728.69Streptomycin Sulfate
CAS:Formel:C21H39N7O12H2O4SFarbe und Form:White To Off-White SolidMolekulargewicht:581.58 3/2 98.08Streptomycin sulfate salt, Ph. Eur. grade
CAS:Formel:C21H39N7O12·5H2SO4Farbe und Form:White to off-white powderMolekulargewicht:728.69Streptomycin sulfate, Antibiotic for Culture Media Use Only
CAS:Streptomycin sulfate is an antibiotic that inhibits the growth of bacteria by binding to the ribosomal subunit and interfering with protein synthesis. It is used in culture media for the production of human antibodies as well as in drug therapy for methicillin-resistant staphylococcus. Streptomycin sulfate has a high specific activity and low sensitivity, but it also has a low solubility in water. The active form of streptomycin sulfate is streptomycin A, which is produced by the addition of a phenyl ring to neomycin sulfate. In plant roots, streptomycin sulfate inhibits cyanogenic glycosides from being hydrolyzed into hydrogen cyanide (HCN) and benzaldehyde.Formel:C42H84N14O36S3Molekulargewicht:1,457.40 g/molRef: 3D-S-8500
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