CAS 69-52-3: Ampicillin-Natrium
Beschreibung:
Ampicillin-Natrium ist ein halbsynthetisches Penicillin-Antibiotikum, das hauptsächlich zur Behandlung einer Vielzahl von bakteriellen Infektionen eingesetzt wird. Es handelt sich um ein weißes bis cremefarbenes kristallines Pulver, das in Wasser löslich ist, was die Verabreichung durch Injektion oder orale Formulierungen erleichtert. Die Verbindung ist ein Natriumsalz von Ampicillin, das seine Stabilität und Löslichkeit verbessert. Ampicillin wirkt, indem es die Synthese der bakteriellen Zellwand hemmt, wodurch es gegen ein breites Spektrum von grampositiven und einigen gramnegativen Bakterien wirksam ist. Sein Wirkmechanismus umfasst die Bindung an Penicillin-bindende Proteine, was zur Zelllyse und zum Absterben der Bakterien führt. Ampicillin-Natrium wird häufig in klinischen Einrichtungen bei Infektionen wie Atemwegsinfektionen, Harnwegsinfektionen und Meningitis eingesetzt. Es ist jedoch wichtig zu beachten, dass einige Bakterien eine Resistenz gegen Ampicillin aufweisen können, was vor der Anwendung Tests auf Empfindlichkeit erforderlich macht. Wie bei jedem Antibiotikum können potenzielle Nebenwirkungen allergische Reaktionen, gastrointestinale Störungen und Veränderungen der normalen Flora umfassen. Eine angemessene Dosierung und Verabreichung sind entscheidend, um das Risiko der Entwicklung von Resistenzen zu minimieren und die therapeutische Wirksamkeit sicherzustellen.
Formel:C16H19N3O4S·Na
InChl:InChI=1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/t9-,10-,11+,14-;/m1./s1
InChI Key:InChIKey=CFOQSNKFOROIKY-YWUHCJSESA-N
SMILES:C(O)(=O)[C@@H]1N2[C@@]([C@H](NC([C@H](N)C3=CC=CC=C3)=O)C2=O)(SC1(C)C)[H].[Na]
Synonyme:- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-, monosodium salt, <span class="text-smallcaps">D</span>-(-)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2α,5α,6β(S*)]]-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-
- 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt, (2S,5R,6R)- (1:1)
- 6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-,sodiumsalt,d-(-)-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid
- <span class="text-smallcaps">D</span>-α-Aminobenzylpenicillin sodium salt
- Alpen-n
- Amcill-s
- Ampi-Dry 5000
- Ampicillin Sodium
- Weitere Synonyme anzeigen
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19 Produkte.
Ampicillin sodium salt
CAS:Ampicillin sodium salt is a reagent for transformed cells expressing beta-lactamase. It acts as a structural analogue of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme and prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formel:C16H18N3NaO4SFarbe und Form:White to pale cream, Powder or crystals or crystalline powderMolekulargewicht:371.39Ampicillin Sodium Salt, Antibiotic for Culture Media Use Only
CAS:Ampicillin is a semisynthetic antibiotic that inhibits bacterial growth by binding to the penicillin-binding protein, which is an enzyme essential for cell wall synthesis. Ampicillin has been shown to be effective against many human pathogens and has a broad spectrum of activity. It is used in culture media for the isolation and cultivation of bacteria. Ampicillin also binds to other proteins such as albumin, hemoglobin, and casein. This drug is usually given orally but can be administered intravenously or intramuscularly. The oral form is a prodrug that must first be metabolized by liver enzymes before becoming active within the body. Ampicillin sodium salt has been shown to have antibacterial efficacy against urinary tract infections caused by Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Enterobacter cloacae, and Enterococcus faecalis.Formel:C16H18N3NaO4SReinheit:Min. 98.0 Area-%Molekulargewicht:371.39 g/molAmpicillin sodium salt
CAS:Formel:C16H18N3NaO4SReinheit:≥ 845μg/mg (anhydrous basis)Farbe und Form:White to off-white or pale yellow powderMolekulargewicht:371.39Ampicillin Sodium
CAS:Ampicillin SodiumFormel:C16H18N3O4S·NaReinheit:Specific optical rotation (Typical Value in Batch COA)Farbe und Form: white or almost white. hygroscopic powderMolekulargewicht:371.39g/molAmpicillin Sodium Salt
CAS:Formel:C16H19N3O4S·NaFarbe und Form:White To Off-White SolidMolekulargewicht:348.40 22.99Ampicillin Sodium Salt (AMP-Na) for tissue culture
CAS:Formel:C16H18N3O4SNaFarbe und Form:White to off-white, Crystalline powder, ClearMolekulargewicht:371.4Ampicillin Sodium
CAS:Kontrolliertes ProduktFormel:C16H18N3O4S·NaFarbe und Form:NeatMolekulargewicht:371.39Ampicillin sodium salt - Bio-X ™
CAS:Ampicillin is a β-lactam antibiotic with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. It is used in the treatment of bacterial infections, including those caused by methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus pneumoniae, and Listeria monocytogenes. Ampicillin binds to penicillin-binding proteins in the bacterial cell wall by competitive inhibition. It prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. Ampicillin sodium salt is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formel:C16H19N3O4S·NaReinheit:Min. 85 Area-%Farbe und Form:PowderMolekulargewicht:372.4 g/molAmpicillin sodium salt
CAS:Reinheit:845~988 mg/mg (Potency, anhydrous basis)Farbe und Form:SolidMolekulargewicht:371.091571336Ampicillin sodium
CAS:Ampicillin sodium is a broad-spectrum antibiotic, which is a semisynthetic derivative of penicillin. It is sourced from the natural fermentation products of Penicillium fungi, followed by chemical modification. Ampicillin functions by inhibiting bacterial cell wall synthesis. This is achieved through the irreversible binding to penicillin-binding proteins (PBPs), which play a crucial role in constructing the peptidoglycan layer of bacterial cell walls. This interruption of cell wall synthesis leads to cell lysis and ultimately the death of the bacteria. Ampicillin sodium is utilized in the medical field primarily to treat a wide variety of bacterial infections, including respiratory tract infections, urinary tract infections, and meningitis. Its efficacy against both Gram-positive and Gram-negative bacteria makes it a valuable option in clinical settings. In addition to its therapeutic applications, ampicillin sodium is often used in microbiological research and laboratory settings as a selection agent in bacterial studies, particularly in the context of genetic engineering and recombinant DNA technology. Its broad spectrum of activity, combined with its relative stability, makes it an essential tool for scientists working in both healthcare and research domains.Formel:C16H18N3O4S·NaReinheit:Min. 95%Farbe und Form:White PowderMolekulargewicht:371.4 g/molAmpicillin Sodium Salt (AMP-Na)
CAS:Formel:C16H18N3O4SNaFarbe und Form:White to off-white, Crystalline powder, ClearMolekulargewicht:371.4Ampicillin sodium
CAS:Ampicillin Sodium, a broad-spectrum aminopenicillin derivative, inhibits bacterial growth by blocking cell wall peptidoglycan synthesis.Formel:C16H18N3NaO4SReinheit:97.34% - 99.26%Farbe und Form:White To Off-White SolidMolekulargewicht:371.39Ampicillin Sodium Salt
CAS:Applications Sodium Salt of Ampicillin, an orally active, semi-synthetic antibiotic; structurally related to penicillin. Antibacterial. References Ivashkiv, E., et al.: Anal. Profiles Drug Subs., 2, 1 (1973), Campoli-Richards, D.M., et al.: Drugs, 33, 577 (1987), Sill, M. L., et al.: Antimicrob. Agents Chemother., 52, 1551 (2008),Formel:C16H18N3O4S·NaFarbe und Form:Off-WhiteMolekulargewicht:371.39Ampicillin sodium salt, EP grade
CAS:Formel:C16H18N3NaO4SReinheit:≤ 2.0%Farbe und Form:White or almost white crystalline powderMolekulargewicht:371.39Ampicillin sodium salt, cell culture grade
CAS:Formel:C16H18N3NaO4SReinheit:≥ 91.0% (anhydrous basis)Farbe und Form:White to light-yellow powderMolekulargewicht:371.39Ampicillin Sodium
CAS:Ampicillin and its saltsFormel:C16H19N3O4S·NaFarbe und Form:White Off-White Crystalline PowderMolekulargewicht:372.0994
