c-Met/HGFR
c-Met/HGFR-Inhibitoren zielen auf den Hepatozyten-Wachstumsfaktor-Rezeptor (c-Met) ab, eine Tyrosinkinase, die an zellulären Prozessen wie Wachstum, Beweglichkeit und Morphogenese beteiligt ist. Die c-Met-Signalgebung ist an der Krebsprogression, Metastasierung und Therapieresistenz beteiligt. Die Hemmung von c-Met kann das Tumorwachstum und die Ausbreitung stören, wodurch diese Inhibitoren in der Krebsforschung wertvoll sind. Bei CymitQuimica bieten wir c-Met/HGFR-Inhibitoren an, um Ihre Forschung in der Onkologie, Metastasierung und bei gezielten Krebstherapien zu unterstützen.
Produkte von "c-Met/HGFR"
Sortieren nach
Canlitinib
CAS:Canlitinib, a tyrosine kinase inhibitor, holds potential for cancer research.Formel:C33H31F2N3O7Reinheit:98%Farbe und Form:SolidMolekulargewicht:619.61SRI 31215 TFA
CAS:SRI 31215 TFA acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation.Formel:C27H34F3N5O3Reinheit:98.25% - 99.97%Farbe und Form:SolidMolekulargewicht:533.6Ref: TM-T5478
1mg43,00€5mg96,00€10mg135,00€25mg261,00€50mg391,00€100mg557,00€200mg753,00€1mL*10mM (DMSO)101,00€1D228
1D228, a c-Met/TRK inhibitor with antitumor properties, suppresses cyclin D1 to precipitate G0/G1 arrest, thereby inhibiting proliferation and migration ofReinheit:98%Farbe und Form:Odour SolidCEP-40783
CAS:CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).Formel:C31H26F2N4O6Reinheit:99.45% - 99.64%Farbe und Form:SolidMolekulargewicht:588.56Merestinib
CAS:Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity.Formel:C30H22F2N6O3Reinheit:95% - 99.56%Farbe und Form:SolidMolekulargewicht:552.53Ref: TM-T3455
1mg49,00€2mg70,00€5mg105,00€10mg144,00€25mg254,00€50mg424,00€100mg605,00€500mg1.264,00€1mL*10mM (DMSO)126,00€PF-04217903
CAS:MET Tyrosine Kinase Inhibitor PF-04217903 is an orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity.Formel:C19H16N8OReinheit:98.41% - 98.55%Farbe und Form:SolidMolekulargewicht:372.38Ref: TM-T2676
1mg38,00€2mg49,00€5mg73,00€10mg97,00€25mg172,00€50mg288,00€100mg520,00€1mL*10mM (DMSO)79,00€Afatinib
CAS:Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formel:C24H25ClFN5O3Reinheit:97.56% - 99.9%Farbe und Form:Off-White SolidMolekulargewicht:485.94Ref: TM-T21312
5mg35,00€10mg51,00€25mg86,00€50mg115,00€100mg144,00€200mg177,00€500mg300,00€1mL*10mM (DMSO)52,00€PROTAC c-Met degrader-1
CAS:PROTACc-Met degrader-1 (Compound Met-DD4) is an orally effective PROTAC degrader targeting c-Met with a DC50 of 6.21 nM. It inhibits the proliferation of c-Met-addicted MKN-45 cells with an IC50 of 4.37 nM and causes cell cycle arrest in the G0/G1 phase. In a xenograft mouse model using MKN-45 cells, PROTACc-Met degrader-1 demonstrates antitumor activity.Formel:C45H41FN10O5Farbe und Form:SolidMolekulargewicht:820.87Onartuzumab
CAS:Onartuzumab (MetMAb) is a humanized monoclonal antibody targeting c-MET, with antitumor effects by blocking HGF and signal transduction.Reinheit:97.3%Farbe und Form:LiquidMolekulargewicht:146.99 kDaEmibetuzumab
CAS:Emibetuzumab: potent humanized MET antibody, antitumor, inhibits HGF/MET pathways, for advanced prostate cancer research.Reinheit:SDS-PAGE:96.2%;SEC-HPLC:98.8%Farbe und Form:LiquidMolekulargewicht:143.74 kDaCabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).Formel:C28H24FN3O5Reinheit:99.59% - 99.88%Farbe und Form:SolidMolekulargewicht:501.51Crizotinib hydrochloride
CAS:Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formel:C21H23Cl3FN5OReinheit:98.73% - 98.87%Farbe und Form:SolidMolekulargewicht:486.8Ref: TM-T8399
5mg37,00€10mg52,00€25mg82,00€50mg99,00€100mg138,00€200mg171,00€500mg227,00€1mL*10mM (DMSO)59,00€c-met-IN-1
CAS:c-met-IN-1 is a potent and selective c-Met inhibitor (IC50: 1.1 nM) with antitumor activity.Formel:C35H37FN6O5Reinheit:98%Farbe und Form:SolidMolekulargewicht:640.7Hepln-13
CAS:Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.Formel:C17H13BrN2Reinheit:97.67%Farbe und Form:SolidMolekulargewicht:325.2Ref: TM-T25492
1mg38,00€2mg50,00€5mg85,00€10mg126,00€25mg245,00€50mg364,00€100mg507,00€200mg700,00€1mL*10mM (DMSO)96,00€Crizotinib
CAS:Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formel:C21H22Cl2FN5OReinheit:99% - 99.87%Farbe und Form:SolidMolekulargewicht:450.34Narnatumab
CAS:Narnatumab (IMC-RON8) is a humanized antibody targeting the macrophage-stimulating receptor (RON) with antitumor activity, used in advanced malignant solid tumors research.Farbe und Form:LiquidSYN1143
CAS:SYN1143 (AMG-1) strongly inhibits RON & c-Met with IC50s: 9 & 4 nmol/L.Formel:C31H29FN4O5Reinheit:98.86%Farbe und Form:SolidMolekulargewicht:556.58SU11274
CAS:SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Formel:C28H30ClN5O4SReinheit:98.62% - 99.44%Farbe und Form:Orange PowderMolekulargewicht:568.09Ref: TM-T6154
1mg47,00€2mg59,00€5mg97,00€10mg150,00€25mg283,00€50mg465,00€100mg688,00€1mL*10mM (DMSO)150,00€SAR125884 hydrochlorid (1116743-46-4(free base))
CAS:SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile,(IC50=4.2 nM).Formel:C25H23FN8O2S2·HClReinheit:97.95%Farbe und Form:SolidMolekulargewicht:587Ref: TM-T5677
1mg38,00€5mg60,00€10mg90,00€25mg188,00€50mg279,00€100mg395,00€200mg567,00€1mL*10mM (DMSO)101,00€Glumetinib
CAS:Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).Formel:C21H17N9O2SReinheit:99.79%Farbe und Form:SolidMolekulargewicht:459.48
