Komplementärsystem
Das Komplementsystem ist ein entscheidender Teil der Immunantwort und besteht aus einer Reihe kleiner Proteine, die die Fähigkeit von Antikörpern und phagozytierenden Zellen verbessern, Krankheitserreger aus einem Organismus zu entfernen. Diese Proteine arbeiten zusammen, um Krankheitserreger zu opsonisieren, entzündliche Reaktionen zu induzieren und die Membranen der Krankheitserreger direkt zu lysieren, wobei sie eine wesentliche Rolle in der angeborenen Immunität und der allgemeinen Immunfunktion spielen. Bei CymitQuimica bieten wir hochwertige Komplementsystem-Proteine an, um Ihre immunologischen Studien und klinischen Forschungen zu unterstützen.
Produkte von "Komplementärsystem"
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C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated
C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated is expressed in E. coli with N-MBP, C-6xHis-Avi. The accession number is P30993.Farbe und Form:Lyophilized PowderMolekulargewicht:52.8 kDa (Predicted)W-54011
CAS:W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Formel:C30H37ClN2O2Reinheit:95.62%Farbe und Form:SolidMolekulargewicht:493.08Ref: TM-T17250
1mg85,00€5mg127,00€10mg187,00€25mg335,00€50mg518,00€100mg747,00€1mL*10mM (DMSO)165,00€C1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formel:C16H22Cl3N5Farbe und Form:SolidMolekulargewicht:390.74C5aR2 agonist P32 acetate
C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.Formel:C54H70N16O11·xC2H4O2Farbe und Form:SolidMolekulargewicht:1119.23 (free base)Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formel:C22H15NO4S2Reinheit:98% - 98.49%Farbe und Form:SolidMolekulargewicht:421.49Iptacopan hydrochloride
CAS:Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.Formel:C25H31ClN2O4Reinheit:98.32% - 99.87%Farbe und Form:SolidMolekulargewicht:458.98Ref: TM-T9189
1mg59,00€5mg127,00€10mg205,00€25mg371,00€50mg620,00€100mg1.026,00€200mg1.388,00€1mL*10mM (DMSO)128,00€C3a (70-77)
CAS:C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.Formel:C35H61N13O10Reinheit:98%Farbe und Form:SolidMolekulargewicht:823.94Danicopan
CAS:Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.Formel:C26H23BrFN7O3Reinheit:99.94%Farbe und Form:SolidMolekulargewicht:580.41Ref: TM-T8509
1mg96,00€2mg136,00€5mg215,00€10mg328,00€25mg557,00€50mg797,00€100mg1.103,00€1mL*10mM (DMSO)274,00€MASP2 Protein, Human, Recombinant (His)
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.Farbe und Form:Lyophilized PowderMolekulargewicht:46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.C1QL1 Protein, Mouse, Recombinant (His)
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.Farbe und Form:Lyophilized PowderMolekulargewicht:26.9 kDa (predicted)(Rel)-Factor B-IN-5
CAS:(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.Formel:C27H32N2O4Reinheit:98.53%Farbe und Form:SolidMolekulargewicht:448.55Complement C3 Protein, Mouse, Recombinant (His)
Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Farbe und Form:Lyophilized PowderMolekulargewicht:36.34 kDa (predicted); 32.39 kDa (reducing conditions)Greziprubart
Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Farbe und Form:Odour LiquidCR1 Protein, Human, Recombinant
CR1 Protein, Human, Recombinant is expressed in E. coli with Tag Free. The accession number is P17927.Farbe und Form:Lyophilized PowderMolekulargewicht:21.6 kDa (Predicted)Complement factor B Protein, Mouse, Recombinant (His)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.Farbe und Form:Lyophilized PowderMolekulargewicht:87.0 kDa (predicted)Cyclosporin A
CAS:Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Formel:C62H111N11O12Reinheit:99.00% - 99.85%Farbe und Form:White PowderMolekulargewicht:1202.61C1q Protein (human)
C1qProtein (human) serves as a subunit in the complement system. It binds to a variety of ligands from self, non-self, and altered-self, contributing to the balance of the immune system, promoting tissue repair, and defending against pathogens.Formel:C19H24N4O3SFarbe und Form:SolidMolekulargewicht:388.48Complement Factor D/CFD Protein, Human, Recombinant (hFc)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Farbe und Form:Lyophilized PowderMolekulargewicht:51.2 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.C1QB Protein, Human, Recombinant (His)
Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system.Farbe und Form:Lyophilized PowderMolekulargewicht:25.2 kDa (predicted); 30 kDa (reducing condition, due to glycosylation)Complement C5 Protein, Cynomolgus, Recombinant (His)
Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Farbe und Form:Lyophilized PowderMolekulargewicht:188.1 kDa (predicted); 106.3 and 75.8 kDa (reducing conditions)
