![2-[3,5-Bis(Trifluoromethyl)Phenyl]-N,2-Dimethyl-N-[4-(2-Methylphenyl)-6-Morpholin-4-Yl-Pyridin-3-Y…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FFB103034.webp&w=3840&q=75)
2-[3,5-Bis(Trifluoromethyl)Phenyl]-N,2-Dimethyl-N-[4-(2-Methylphenyl)-6-Morpholin-4-Yl-Pyridin-3-Yl]Propanamide
CAS:
Ref. 3D-FB103034
Produktinformation
Name:2-[3,5-Bis(Trifluoromethyl)Phenyl]-N,2-Dimethyl-N-[4-(2-Methylphenyl)-6-Morpholin-4-Yl-Pyridin-3-Yl]Propanamide
Marke:Biosynth
Beschreibung:2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-morpholin-4-ylpyridin-3-yl]propanamide is a serotonin receptor antagonist that blocks the binding of serotonin to its receptors. It is used in the treatment of chronic cough and emetogenic chemotherapy. Netupitant is also an antagonist of the NK1 receptor and is used in combination with other antiemetics for cancer patients receiving high doses of emetogenic chemotherapy. Netupitant has been shown to have an antidepressant effect, which may be due to its ability to inhibit the release of serotonin from platelets. Netupitant may also cause some side effects such as nausea, vomiting, diarrhea, constipation, or headache. These side effects are usually temporary and can be minimized by taking the drug with food or milk.
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Chemische Eigenschaften
Molekulargewicht:565.55 g/mol
Formel:C29H29F6N3O2
Reinheit:Min. 95%
InChl:InChI=1S/C29H29F6N3O2/c1-18-7-5-6-8-22(18)23-16-25(38-9-11-40-12-10-38)36-17-24(23)37(4)26(39)27(2,3)19-13-20(28(30,31)32)15-21(14-19)29(33,34)35/h5-8,13-17H,9-12H2,1-4H3
InChI Key:InChIKey=ZGNPLCMMVKCTHM-UHFFFAOYSA-N
SMILES:Cc1ccccc1-c1cc(N2CCOCC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1