CAS: 1001913-13-8

VCH-759 is a nucleoside analog that is a potential treatment for chronic hepatitis C. VCH-759 inhibits the NS5B polymerase of the hepatitis C virus, an enzyme responsible for viral replication. It binds to the active site of NS5B and prevents it from functioning. VCH-759 has shown antiviral effects in cell culture and animal models and has a safety profile comparable to other nucleoside analogs. The drug also appears to be effective against other types of viruses, including HIV, influenza A, and herpes simplex virus type 2. VCH-759 may be used as a single agent or in combination with other antivirals to treat patients with chronic viral infections.