CAS: 10027-65-3

Organo-sulfur compounds, nesoi

Amifostine is a disulfide tetrahydrochloride salt that is used as an antidote to protect the bone marrow during chemotherapy and radiotherapy. Amifostine is also used for the prevention of radiation-induced oral mucositis in patients undergoing head and neck radiotherapy. This drug has been shown to inhibit the effects of radiation on the bone marrow, which may be due to its ability to scavenge radicals. Amifostine also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.