CAS 104376-79-6: Ceftriaxona disódica hemiheptahidrato
Descripción:
Ceftriaxona disódica hemiheptahidrato es un antibiótico cefalosporínico de amplio espectro utilizado principalmente para el tratamiento de diversas infecciones bacterianas. Se caracteriza por su forma de sal disódica, que mejora su solubilidad en agua, haciéndolo adecuado para la administración intravenosa o intramuscular. La forma de hemiheptahidratado indica que el compuesto contiene siete moléculas de agua por molécula de ceftriaxona disódica, lo que contribuye a su estabilidad y solubilidad. La ceftriaxona es efectiva contra una amplia gama de bacterias Gram-positivas y Gram-negativas, incluyendo cepas resistentes a otros antibióticos. Su mecanismo de acción implica la inhibición de la síntesis de la pared celular bacteriana, lo que lleva a la lisis celular y la muerte. El compuesto generalmente es bien tolerado, aunque puede causar efectos secundarios como reacciones alérgicas o trastornos gastrointestinales en algunos pacientes. Además, es importante monitorear la función renal durante el tratamiento, ya que la ceftriaxona se excreta principalmente por los riñones. En general, Ceftriaxona disódica hemiheptahidrato es un agente terapéutico vital en la medicina moderna, particularmente en el tratamiento de infecciones severas.
Fórmula:C18H18N8O7S3H2O·2Na
InChI:InChI=1S/C18H18N8O7S3.2Na.3H2O/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7;;;;;/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32);;;3*1H2/b24-8-;;;;;/t9-,15-;;;;;/m1...../s1
Clave InChI:InChIKey=UVEYQVBFLCMIMX-PMCOHIMVSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1CSC=4N(C)NC(=O)C(=O)N4)[H].[Na].O
Sinónimos:- (6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-(O-methyloxime), disodium salt, sesquaterhydrate
- (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, disodium salt, (6R-(6alpha,7beta(Z)))-, hydrate (2:7)
- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, disodium salt, hydrate (2:7), (6R-(6alpha,7beta(Z))-
- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, disodium salt, hydrate (2:7), (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, disodium salt, hydrate (2:7), [6R-[6α,7β(Z)]]-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, sodium salt, hydrate (2:4:7), (6R,7R)-
- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2E)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, monosodium salt, monohydrate
- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-[[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-1,2,4-triazin-3-yl)thio]methyl]-8-oxo-, sodium salt, (6R,7R)- (1:1)
- Ceftriaxone disodium hemiheptahydrate
- Ceftriaxone disodium salt hemiheptahydrate
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CEFTRIAXONE SODIUM CRS
CAS:CEFTRIAXONE SODIUM CRSFórmula:C10H16N2O2Forma y color:Added ModifiedPeso molecular:196.2462Ceftriaxone Disodium Salt Hemiheptahydrate (CFTZ) ExiPlus, Multi-Compendial
CAS:Fórmula:C18H16N8Na2O7S3·5H2OPeso molecular:661.60Ceftriaxone disodium salt, 50 mg/ml in distilled water
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Ceftriaxone Disodium Salt Hemiheptahydrate
CAS:Fórmula:C18H16N8Na2O7S3H2OPureza:>98.0%(T)(HPLC)Forma y color:White to Orange to Green powder to crystalPeso molecular:661.58Ceftriaxone disodium hemiheptahydrate
CAS:Ceftriaxone disodium hemiheptahydrate is a third-generation cephalosporin antibiotic, which is a semisynthetic derivative of cephalosporin C. This compound is sourced from the fungus Acremonium, which is known for its role in deriving crucial β-lactam antibiotics. Ceftriaxone acts by inhibiting bacterial cell wall synthesis, specifically targeting the penicillin-binding proteins (PBPs). This action disrupts peptidoglycan cross-linking, leading to bacterial cell lysis and death. The primary applications of ceftriaxone include the treatment of severe or life-threatening forms of bacterial infections such as meningitis, septicemia, and pneumonia. Its broad-spectrum activity covers a range of Gram-positive and Gram-negative bacteria. Ceftriaxone's extended half-life allows for once-daily dosing, making it particularly useful in clinical settings where adherence to a multi-dose regimen is challenging. Its pharmacokinetics and spectrum make it a preferred choice in empirical therapy while awaiting culture and sensitivity results. As with all antibiotics, judicious use is essential to mitigate the development of antimicrobial resistance.Fórmula:(C18H18N8Na2O7S3)2•(H2O)7Pureza:Min. 94 Area-%Forma y color:White Yellow PowderPeso molecular:1,327.23 g/molCeftriaxone Sodium Hemiheptahydrate
CAS:Producto controladoFórmula:C18H16N8O7S3NaH2OForma y color:NeatPeso molecular:1323.19Ceftriaxone sodium hemiheptahydrate
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C36H46N16Na4O21S6Pureza:98%Forma y color:White to pale cream or pale yellow, Crystals or powder or crystalline powderPeso molecular:1323.17Ceftriaxone sodium hydrate
CAS:Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.Fórmula:C18H16N8Na2O7S3·5H2OPureza:99.77% - 99.78%Forma y color:White Or Almost White Crystalline Powder OdorlessPeso molecular:661.6Ceftriaxone disodium salt hemi(heptahydrate)
CAS:Fórmula:C18H16N8Na2O7S3·5H2OPureza:95.0 - 102.0 % (anhydrous basis)Forma y color:White or pale yellow crystalline powderPeso molecular:661.60Ceftriaxone sodium
CAS:Ceftriaxone sodiumFórmula:C18H16N8Na2O7S3Pureza:88.6%Forma y color:White To Off-WhitePeso molecular:598.00995Ceftriaxone Disodium Salt Hemiheptahydrate (CFTZ)
CAS:Fórmula:C18H16N8Na2O7S3·5H2OForma y color:White to yellow, Crystalline powderPeso molecular:661.60Ceftriaxone Disodium Salt Hemiheptahydrate
CAS:Applications An antibacterial, a third-generation cephalosporin. References Reiner, R., et al.: J. Antibiot., 33, 783 (1980)Fórmula:C18H18N8Na2O7S3H2OForma y color:White To Off-WhitePeso molecular:1323.19Ceftriaxone sodium hemiheptahydrate
CAS:Producto controladoFórmula:C18H16N8O7S3NaH2OForma y color:NeatPeso molecular:1323.19Ceftriaxone sodium salt hemiheptahydrate
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C36H46N16Na4O21S6Forma y color:White to light yellow, Crystalline powderPeso molecular:1323.17Ceftriaxone sodium hydrate - Bio-X ™
CAS:Ceftriaxone is a broad-spectrum cephalosporin antibiotic that is used for the treatment of bacterial infections in different locations such as the skin, soft tissue and respiratory tract. This drug works by inhibiting mucopeptide synthesis in the bacterial cell wall. As a result, bacteria will produce defective cell walls leading to cell death. Ceftriaxone disodium salt hemiheptahydrate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C18H16N8Na2O7S3·5H2OPureza:Min. 95%Forma y color:PowderPeso molecular:661.6 g/mol
