CAS 108321-42-2: Sulfato de geneticina
Descripción:
Sulfato de geneticina, también conocido como G418, es un antibiótico aminoglucósido que se utiliza principalmente en biología molecular para la selección de células genéticamente modificadas. Es efectivo contra una amplia gama de bacterias y es particularmente conocido por su capacidad para inhibir la síntesis de proteínas al unirse a la subunidad ribosómica 30S. Este compuesto se utiliza a menudo en cultivos celulares para seleccionar células que han sido transfectadas con plásmidos que contienen un marcador genético para la resistencia a Geneticin. La forma sulfato mejora su solubilidad en soluciones acuosas, lo que lo hace adecuado para aplicaciones de laboratorio. Geneticin se utiliza típicamente a concentraciones que varían según el tipo de célula y las condiciones experimentales. Es importante manejar Sulfato de geneticina con cuidado, ya que puede ser tóxico para las células no resistentes. Además, debido a sus propiedades antibióticas, es crucial considerar los efectos potenciales sobre la flora microbiana en los montajes experimentales. En general, Sulfato de geneticina es una herramienta valiosa en la ingeniería genética y la investigación en biología celular.
Fórmula:C20H40N4O10·2H2O4S
InChI:InChI=1S/C20H40N4O10.H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;(H2,1,2,3,4)/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+;/m1./s1
Clave InChI:InChIKey=QNQZPJLBGRQFDD-ZMSORURPSA-N
SMILES:O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@]([C@@H](C)O)([C@@H](O)[C@H](O)[C@H]2N)[H])[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3.S(=O)(=O)(O)O
Sinónimos:- (2R,3S,4R,5R,6S)-5-amino-6-[(1S,2R,4S,6R)-4,6-diamino-3-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-2-(1-hydroxyethyl)tetrahydropyran-3,4-diol
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,7-dideoxy-<smallcap>D</smallcap>-glycero-α-<smallcap>D</smallcap>-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2) (salt)
- ANTIBIOTIC G-418 Sulfate
- G-418 Sulfate
- G-418 Sulphate
- G418 Disulfate Cell Culture Tested
- G418 Disulfate Plant Cell Culture Tested
- G418 Solution
- G418 Sulfate
- Geneticin sulfate
- Ver más sinónimos
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Encontrado 19 productos.
G 418 disulfate salt
CAS:Fórmula:C20H44N4O18S2Pureza:98%Forma y color:SolidPeso molecular:692.7093600000002Geneticin sulfate
CAS:Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.Fórmula:C20H40N4O10·2H2SO4Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:692.71 g/molG418 Disulfate
CAS:Fórmula:C20H40N4O10·2H2SO4Pureza:>90.0%(HPLC)(N)Forma y color:White to Almost white powder to crystalPeso molecular:692.70G-418 Disulphate
CAS:G-418 DisulphateFórmula:C20H40N4O10·2H2SO4Pureza:The product has been tested (Typical Value in Batch COA)Forma y color: solidPeso molecular:692.71g/molG-418.Sulfate Solid
CAS:M01801 - G-418.Sulfate SolidFórmula:C20H44N4O18S2Pureza:>90.0%(HPLC)(N)Forma y color:SolidPeso molecular:692.7000122070312G418 disulfate, 50mg/ml solution
CAS:G418 disulfate is used for selection and maintenance of prokaryotic and eukaryotic cells transfected with a iNOS promoter construct and neomycin resistance gene. Optimal concentrations for selection and maintenance vary by cell lines. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C20H44N4O18S2Forma y color:Clear colorless, LiquidPeso molecular:692.70G-418 disulfate
CAS:G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in cells.Fórmula:C20H40N4O10·2H2O4SPureza:98% - 99.9%Forma y color:White To Off-White PowderPeso molecular:692.71G418 sulfate, for biochemistry
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C20H44N4O18S2Forma y color:Powder, White to off-whitePeso molecular:692.70G418 disulfate, Cell Culture Reagent
CAS:G418 disulfate is an aminoglycoside that is toxic to bacteria, yeast, protozoans and helminths. It prevents protein synthesis by blocking the elongation step in prokaryotic and eukaryotic ribosomes. It is used as a selection agent for G418 resistant bacteria or fungi after transformation. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C20H44N4O18S2Forma y color:White, PowderPeso molecular:692.70G418 disulphate salt
CAS:Fórmula:C20H40N4O10·2H2SO4Pureza:≥ 720μg/mgForma y color:White to almost white powderPeso molecular:692.71G-418.Sulfate, Sterile-Filtered Solution
CAS:M01802 - G-418.Sulfate, Sterile-Filtered SolutionFórmula:C20H44N4O18S2Pureza:>90.0%(HPLC)(N)Forma y color:LiquidPeso molecular:692.7000122070312G418 disulphate salt, 10% solution in water
CAS:Fórmula:C20H40N4O10·2H2SO4Forma y color:Clear, colourless liquidPeso molecular:692.71Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only
CAS:Geneticin is very efficient against gram-negative bacteria, however it is not applied for treating infections due to high renal toxicity. Geneticin and its resistance genes found application in the selection of transgenic cell lines including yeasts such as P. pastoris and S. serevisiae, other eukaryotic cell lines such as CHO or HEK293, but also plant cells and bacterial cells.Fórmula:C20H44N4O18S2Pureza:Min. 97.0 Area-%Peso molecular:692.71 g/molRef: 3D-G-2400
10gA consultar25gA consultar50gA consultar100gA consultar250gA consultar-Unit-ggA consultarG-418 Sulphate (Geneticin) extrapure
CAS:Fórmula:C20H40N4O10·2H2SO4Forma y color:White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellowPeso molecular:692.70G-418 Sulphate (Geneticin) for tissue culture
CAS:Fórmula:C20H40N4O10·2H2SO4Forma y color:White to off-white, Crystalline powder, Clear to slightly hazy, Colourless to pale yellowPeso molecular:692.70G-418 Sulphate solution 50mg/ml
CAS:G-418 Sulphate solution 50mg/mlForma y color:SolutionPeso molecular:594.63g/mol
