CAS 11021-14-0: ginsenósido rc
Descripción:
ginsenósido rc es un compuesto natural clasificado como una saponina triterpenoide, que se encuentra principalmente en especies de ginseng, particularmente en Panax ginseng. Es uno de los muchos ginsenósidos, que son constituyentes bioactivos que se cree que contribuyen a los efectos farmacológicos del ginseng. ginsenósido rc se caracteriza por su estructura compleja, que presenta un esqueleto de dammarano con patrones de glicosilación específicos que influyen en su actividad biológica. Este compuesto es conocido por sus posibles beneficios para la salud, incluyendo propiedades antiinflamatorias, antioxidantes y neuroprotectoras. La investigación ha indicado que ginsenósido rc puede mejorar la función cognitiva y exhibir efectos cardioprotectores. Además, se ha estudiado por su papel en la modulación de diversas vías de señalización, lo que podría ser relevante en el contexto de enfermedades como el cáncer y la diabetes. Debido a sus diversas actividades farmacológicas, ginsenósido rc es de gran interés tanto en la medicina tradicional como en la farmacología moderna, aunque se necesitan más estudios para elucidar completamente sus mecanismos de acción y potencial terapéutico.
Fórmula:C53H90O22
InChI:InChI=1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-68-45-41(65)36(60)28(21-56)69-45)24-11-16-52(7)33(24)25(57)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)35(59)27(20-55)71-48)74-46-42(66)38(62)34(58)26(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3/t24-,25+,26+,27+,28-,29+,30-,31+,32-,33-,34+,35+,36-,37+,38-,39-,40-,41+,42+,43+,44+,45+,46-,47-,48-,50-,51+,52+,53-/m0/s1
Clave InChI:InChIKey=JDCPEKQWFDWQLI-LUQKBWBOSA-N
SMILES:C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](CO)O4)CC3)[H])(C[C@@H](O)[C@]6([C@@]2(C)CC[C@@]6([C@@](O[C@@H]7O[C@H](CO[C@@H]8O[C@@H](CO)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)(CCC=C(C)C)C)[H])[H])[H]
Sinónimos:- (3β,12β)-20-[(6-O-α-<span class="text-smallcaps">L</smallcap>-Arabinofuranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
- 12-hydroxy-20-[(6-O-pentofuranosylhexopyranosyl)oxy]dammar-24-en-3-yl 2-O-hexopyranosylhexopyranoside
- Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
- Ginsenoside Rc, Ginsenoside Rb2
- NSC 310104
- Panaxoside Rc
- β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β)-20-[(6-O-α-<smallcap>L</smallcap>-arabinofuranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
- Ginsenoside Rc
- Dammarane, β-D-glucopyranoside deriv.
- β-D-Glucopyranoside, (3β,12β)-20-[(6-O-α-L-arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
- (3β,12β)-20-[(6-O-α-L-Arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
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Ginsenoside rc
CAS:Natural glycosideFórmula:C53H90O22Pureza:≥ 90.0 % (HPLC)Forma y color:PowderPeso molecular:1079.29Ginsenoside Rc
CAS:Ginsenoside Rc (Rc), a protopanaxadiol type ginsenoside, is the active component mainly responsible for the therapeutic and pharmacologic properties of ginseng, which are derived from its suppression of superoxide-induced free radicals, Rc can modulate Forkhead box O (FoxO1)phosphorylation through activation of PI3K/Akt and inhibition of AMPK and FoxO1 acetylation through interaction with CBP and SIRT1, and that this leads to upregulation of catalase under conditions of oxidative stress.Fórmula:C53H90O22Pureza:95%~99%Forma y color:White powderPeso molecular:1079.28Ginsenoside Rc
CAS:Producto controladoStability Hygroscopic Applications Ginsenoside Rc displays anti-proliferative effects in human breast cancer cell lines. References Lee, Y. et al.: Arch. Pharm. Res., 26, 53 (2003);Fórmula:C53H90O22Forma y color:White To Light YellowPeso molecular:1079.27Ginsenoside Rc
CAS:Ginsenoside Rc analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C53H90O22Pureza:(HPLC) ≥98%Forma y color:PowderPeso molecular:1079.29Ginsenoside Rc
CAS:Ginsenoside Rc is a bioactive compound, which is a triterpenoid saponin derived from the root of the Panax ginseng plant. It possesses a unique mode of action through its interaction with cell membrane receptors, influencing various signaling pathways. Among its many effects, Ginsenoside Rc modulates immune response, exhibits antioxidant properties, and can regulate glucose metabolism and cardiovascular function. This ginsenoside is studied for its potential applications in medicine, including its neuroprotective and anticancer activities. In neurological studies, Ginsenoside Rc has shown promise in protecting neural cells against injury and degeneration, possibly offering therapeutic benefits for conditions such as Alzheimer's and Parkinson's diseases. Additionally, its ability to inhibit cancer cell proliferation and induce apoptosis highlights its potential role in cancer therapy. Research continues to explore the full spectrum of Ginsenoside Rc's pharmacological properties and its potential integration into clinical practice, with a strong interest in its synergistic effects when combined with other bioactive ginsenosides.Fórmula:C53H90O22Pureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:1,079.3 g/mol
