CAS 110429-35-1: Clorhidrato de paroxetina hemihidrato
Descripción:
Clorhidrato de paroxetina hemihidrato es un inhibidor selectivo de la recaptación de serotonina (ISRS) utilizado principalmente en el tratamiento del trastorno depresivo mayor, trastornos de ansiedad y trastorno obsesivo-compulsivo. Se caracteriza por su fórmula química, que incluye una forma de sal de clorhidrato y un hemihidrato, lo que indica la presencia de moléculas de agua en su estructura cristalina. Este compuesto típicamente aparece como un polvo blanco a blanco amarillento y es soluble en agua, lo que facilita su absorción en el cuerpo. La paroxetina actúa inhibiendo la recaptación de serotonina en el cerebro, aumentando así los niveles de serotonina y mejorando el estado de ánimo. La forma de hemihidrato sugiere que contiene media molécula de agua por cada molécula de clorhidrato de paroxetina, lo que puede influir en su estabilidad y solubilidad. Al igual que con muchos fármacos, es esencial manejar Clorhidrato de paroxetina hemihidrato con cuidado, siguiendo las pautas de seguridad para evitar posibles efectos secundarios e interacciones con otros medicamentos.
Fórmula:C19H20FNO3·ClHH2O
InChI:InChI=1S/C19H20FNO3.ClH.H2O/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;;/h1-6,9,14,17,21H,7-8,10-12H2;1H;1H2/t14-,17-;;/m0../s1
Clave InChI:InChIKey=QRQSGFFISBKLMZ-YHOFXEKLSA-N
SMILES:C(OC=1C=C2C(=CC1)OCO2)[C@H]3[C@@H](CCNC3)C4=CC=C(F)C=C4.Cl.O
Sinónimos:- (-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidine hydrochloride hemihydrate
- (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride (1:1)
- (3s-trans)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride Hemihydrate
- (4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride (1:1)
- Paroxetine-D4 Hcl
- Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:1), (3S,4R)-
- Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:1), (3S-trans)-
- Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:2:1), (3S,4R)-
- paroxetine hydrochloride Hemihydrate
- Paroxetine HCl,Hemihydrate
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Paroxetine hydrochloride hemihydrate CRS
CAS:Paroxetine hydrochloride hemihydrate CRSFórmula:C38H44Cl2F2N2O7Forma y color:Crystalline Powder. White. Powder.Peso molecular:749.668Paroxetine hydrochloride hemihydrate, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C19H20FNO3Pureza:98%Forma y color:White, Crystalline powderPeso molecular:329.37Paroxetine HCl
CAS:Fórmula:C19H20FNO3·HClForma y color:White To Off-White SolidPeso molecular:329.37 36.46Paroxetine Hydrochloride Hemihydrate 1.0 mg/ml in Methanol (as anhydrous free base)
CAS:Fórmula:C19H20FNO3·2ClH·H2OParoxetine HCl (hemihydrate)
CAS:Producto controladoA serotonin reuptake inhibitor with anticholinergic activity and mild inhibitory activity on noradrenaline reuptake. Paroxetine has been used for the treatment of depression, anxiety disorders, post-traumatic stress disorder, premenstrual dysphoric disorder and obsessive-compulsive disorder. Also inhibits nitric oxide synthase and cytochrome isoenzyme P450 2D6.Fórmula:C19H20FNO3•HCl•(H2O)0Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:374.83 g/molParoxetine hydrochloride hemihydrate
CAS:Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).Fórmula:C38H44Cl2F2N2O7Pureza:100%Forma y color:SolidPeso molecular:749.67Paroxetine Hydrochloride Hemihydrate
CAS:Fórmula:C19H20FNO3HCl(H2O)Peso molecular:329.4 : 36.46 : 1/2(18.0)Paroxetine HCl hemihydrate - Bio-X ™
CAS:Producto controladoParoxetine belongs to a class of drugs called selective serotonin reuptake inhibitors. It is used as an antidepressant and anxiolytic agent but also for post-traumatic stress disorder, premenstrual dysphoric disorder and obsessive-compulsive disorder. Paroxetine inhibits the activity of the enzyme, which is responsible for the re-uptake of serotonin in nerve cells and thus increases its concentration in the synaptic space. Additionally, it inhibits nitric oxide synthase and cytochrome isoenzyme P450 2D6. Paroxetine HCl hemihydrate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C19H20FNO3·HClH2OPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:374.83 g/molParoxetine Hydrochloride
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C19H20FNO3·HClH2OForma y color:White Off-White Crystalline PowderPeso molecular:329.14272Paroxetine hydrochloride hemihydrate
CAS:Paroxetine hydrochloride hemihydratePureza:≥98%Peso molecular:749.67g/molParoxetine Hydrochloride Hemihydrate
CAS:Paroxetine Hydrochloride HemihydratePeso molecular:374.83g/molParoxetine hydrochloride hemihydrate
CAS:Paroxetine hydrochloride hemihydrateFórmula:C19H20FNO3HClPureza:97.4%Forma y color:Off-WhitePeso molecular:365.1194USP Paroxetine Related Compound E Mixture
CAS:Producto controladoApplications USP Paroxetine Related Compound E Mixture is a reference standard composed of Paroxetine Hydrochloride (P205750) spiked with 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methyl-pyridine Hydrochloride (F595220). Paroxetine Hydrochloride (P205750) is a selective serotonin reuptake inhibitor. Used as an antidepressant. 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methyl-pyridine Hydrochloride (F595220) is the active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (M325910), N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982); Gerlach, M., et al.: Eur. J. Pharmacol., 208, 273 (1991), Tipton, K., et al.: J. Neurochem., 61, 1191 (1993), Wimalasena, D., et al.: J. Biol. Chem., 279, 15298 (2004),Fórmula:C19H20FNO3·C12H14FN·HClForma y color:NeatPeso molecular:557.07
