CAS 113507-06-5: Moxidectina
Descripción:
Moxidectina es un lactona macrocíclica semisintética que pertenece a la clase de compuestos conocidos como avermectinas, que se derivan de la fermentación de la bacteria Streptomyces avermitilis. Se utiliza principalmente como agente antiparasitario, particularmente en medicina veterinaria, para el tratamiento de diversas infecciones parasitarias en animales, incluyendo nematodos y ectoparásitos. Moxidectina exhibe un amplio espectro de actividad y es conocido por su prolongada duración de acción, lo que permite una dosificación menos frecuente en comparación con otros agentes antiparasitarios. El compuesto actúa uniéndose a los canales de cloruro activados por glutamato en el sistema nervioso de los parásitos, lo que lleva a la parálisis y muerte del organismo. Moxidectina se administra típicamente por vía oral o mediante inyección, y su farmacocinética se caracteriza por una buena absorción y distribución en los tejidos. Es importante señalar que, aunque Moxidectina es efectivo contra muchos parásitos, no es efectivo contra todos, y su uso debe ser guiado por recomendaciones veterinarias para garantizar la seguridad y eficacia.
Fórmula:C37H53NO8
InChI:InChI=1/C37H53NO8/c1-21(2)14-25(6)33-26(7)31(38-42-8)19-36(46-33)18-29-17-28(45-36)13-12-23(4)15-22(3)10-9-11-27-20-43-34-32(39)24(5)16-30(35(40)44-29)37(27,34)41/h9-12,14,16,21-22,26,28-30,32-34,39,41H,13,15,17-20H2,1-8H3/b10-9+,23-12+,25-14+,27-11+,38-31-/t22-,26-,28+,29-,30-,32+,33+,34+,36-,37+/m0/s1
Clave InChI:InChIKey=YZBLFMPOMVTDJY-LSGXYNIPSA-N
SMILES:C(=C\C(C)C)(\C)/[C@H]1O[C@@]2(C[C@@]3(C[C@](O2)(C/C=C(\C)/C[C@@H](C)/C=C/C=C\4/[C@@]5(O)[C@](C(=O)O3)(C=C(C)[C@@H](O)[C@]5(OC4)[H])[H])[H])[H])C/C(=N\OC)/[C@@H]1C
Sinónimos:- (2aE,4E,4'E,5'S,6R,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-4'-(methoxyimino)-5',6,8,19-tetramethyl-6'-[(2E)-4-methylpent-2-en-2-yl]-3',4',5',6,6',7,10,11,14,15,17a,20,20a,20b-tetradecahydro-2H,17H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-17-one
- (6R,23E,25S)-5-O-Demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-(methoxyimino)milbemycin B
- 23-Methoxime-LL-F 28249α
- 5-O-demethyl-28-deoxy-25-(1E)-1,3-dimethyl-1-butenyl-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
- Cl 301423
- Cydectin
- Equest
- Milbemycin B, 5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-(methoxyimino)-, [6R,23E,25S(E)]-
- Milbemycin B, 5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
- Milbemycin B, 5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
- MilbemycinB
- Ver más sinónimos
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Moxidectin for system suitability CRS
CAS:Moxidectin for system suitability CRSFórmula:C37H53NO8Forma y color:PowderPeso molecular:639.8186Moxidectin 100 µg/mL in Acetonitrile
CAS:Fórmula:C37H53NO8Forma y color:Single SolutionPeso molecular:639.82Smart Solutions™ v59 PharmaVetResiMix Kit 1
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Forma y color:MixtureMoxidectin
CAS:Fórmula:C37H53NO8Pureza:≥ 95.0%Forma y color:White to off-white or yellow powderPeso molecular:639.82Moxidectin
CAS:MoxidectinFórmula:C37H53NO8Pureza:94.2%Forma y color:Off-WhitePeso molecular:639.37712Moxidectin
CAS:Moxidectin is a milbemycin derivative that belongs to the class of macrocyclic lactones. It is used in veterinary medicine to treat infections caused by Diptera larvae, such as the sheep blowfly, Lucilia sericata. Moxidectin has been shown to be an effective drug against c. glabrata, which is resistant to ivermectin and other drugs. Moxidectin binds to P-glycoprotein substrate site 1 and prevents drug efflux from cells by competing with other substrates for binding sites on the transporter. This inhibition of drug efflux may be due to its ability to block P-glycoprotein function or act as a direct inhibitor of ATPase activity. The analytical method used in this study was high performance liquid chromatography (HPLC).Fórmula:C37H53NO8Pureza:Min. 92 Area-%Forma y color:White PowderPeso molecular:639.82 g/molMoxidectin
CAS:Fórmula:C37H53NO8Pureza:>98.0%(N)Forma y color:White to Almost white powder to crystalPeso molecular:639.83Moxidectin - Bio-X ™
CAS:This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C37H53NO8Pureza:Min. 95%Forma y color:PowderPeso molecular:639.82 g/molMoxidectin
CAS:Applications Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005);Fórmula:C37H53NO8Forma y color:White To Off-WhitePeso molecular:639.82Moxidectin-d3
CAS:Producto controladoStability Light Sensitive Applications Moxidectin-d3 is a the labelled form of Moxidectin (M744800). Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005)Fórmula:C37H50D3NO8Forma y color:White SolidPeso molecular:642.84Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
CAS:Fórmula:C37H53NO8Pureza:96%Forma y color:SolidPeso molecular:639.8186LC PestiMix 2 10 µg/mL in Acetonitrile
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Forma y color:Mixture
![Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-,…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00HCQ4.jpg&w=3840&q=75)
