CAS 114-49-8: Bromhidrato de escopolamina
Descripción:
Bromhidrato de escopolamina es un alcaloide tropano derivado de plantas de la familia Solanaceae, particularmente de la planta de belladona. Es un polvo cristalino blanco a blanco amarillento que es soluble en agua y alcohol, lo que lo hace adecuado para diversas formulaciones farmacéuticas. La sustancia actúa principalmente como un agente anticolinérgico, bloqueando la acción de la acetilcolina en el sistema nervioso, lo que la hace efectiva en el tratamiento del mareo por movimiento, náuseas y vómitos. Bromhidrato de escopolamina también se utiliza en entornos preoperatorios para reducir la salivación y las secreciones. Sus efectos farmacológicos incluyen sedación, amnesia y relajación muscular, pero también puede causar efectos secundarios como boca seca, visión borrosa y somnolencia. Debido a su potencial de abuso y al riesgo de efectos secundarios severos, su uso se monitorea cuidadosamente en entornos clínicos. Al igual que con cualquier medicamento, es esencial usar Bromhidrato de escopolamina bajo la guía de un profesional de la salud para garantizar la seguridad y eficacia.
Fórmula:C17H21NO4·BrH
InChI:InChI=1S/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1
Clave InChI:InChIKey=WTGQALLALWYDJH-MOUKNHLCSA-N
SMILES:CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].Br
Sinónimos:- (-)-Scopolamine bromide
- (-)-Scopolamine, HBr
- (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl 3-hydroxy-2-phenylpropanoate hydrobromide (1:1)
- 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
- 3-Oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]nonane, benzeneacetic acid deriv.
- 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrobromide (1:1)
- 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrochloride
- Beldavrin
- Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide (1:1), (αS)-
- Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide, (αS)-
- Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
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Encontrado 8 productos.
Scopolamine HBr (Hyoscine HBr)
CAS:Fórmula:C17H21NO4·HBrForma y color:White To Off-White SolidPeso molecular:303.36 80.91Scopolamine-13C, D3 Hydrobromide
CAS:Producto controladoApplications Scopolamine-13C, d3 Hydrobromide, is the labeled analogue of Scopolamine-d3 Hydrobromide (S200002), an acetylcholine antagonist, used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),Fórmula:C1613CH19D3BrNO4Forma y color:Off-WhitePeso molecular:388.28Scopolamine Hydrobromide Trihydrate
CAS:Fórmula:C17H21NO4·HBr·3H2OPureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:438.32Scopolamine Hydrobromide Hydrate
CAS:Producto controladoApplications Scopolamine Hydrobromide Hydrate is an acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Neuroprotective & Neuroresearch Product. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brand, J.J., et al.: Lancet, 2, 232 (1970); Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979); Clissold, S.P., et al.: Drugs, 29, 189 (1985); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990);Fórmula:C17H21NO4·HBr·xH2OForma y color:White SolidPeso molecular:384.26(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide
CAS:(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromidePeso molecular:438.31g/molScopolamine hydrobromide
CAS:Scopolamine hydrobromide is an anticholinergic medication, which is a derivative of tropane alkaloids sourced primarily from Solanaceae family plants, such as Hyoscyamus niger and Datura stramonium. Its mode of action involves competitive inhibition of acetylcholine at muscarinic receptors in the central and peripheral nervous systems. This blocking effect impedes parasympathetic nerve impulses, leading to diminished activity in smooth muscles and glandular secretions. This compound is extensively used in clinical settings for the prevention and treatment of motion sickness and postoperative nausea and vomiting. Its ability to cross the blood-brain barrier makes it effective in influencing central nervous system activities, particularly within the vestibular pathways. Additionally, it has applications in ophthalmology for pupil dilation due to its mydriatic effect. The understanding of its molecular interactions and effects on neurotransmitter pathways is crucial for advancing therapeutic uses, as well as minimizing potential side effects such as dry mouth and blurred vision.Fórmula:C17H21NO4·HBrPureza:Min. 95%Forma y color:PowderPeso molecular:384.26 g/molScopolamine hydrobromide
CAS:Natural alkaloidFórmula:C17H21NO4HBrPureza:≥ 95.0 % (HPLC)Forma y color:PowderPeso molecular:384.27
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