CAS: 1173021-73-2

Applications A labelled β2-adrenoceptor agonist. Bronchodilator; tocolytic. References Miyagawa, N., et al.: Biol. Pharm. Bull., 31, 2260 (2008), Gonzalez-Munoz, C., et al.: Eur. J. Pharmacol., 607, 151 (2009), Kern, C., et al.: J. Med. Chem., 52, 1773 (2009),

Salbutamol-d9 is a racemic mixture of the two enantiomers of salbutamol. It is used as an inhalation bronchodilator for the treatment of asthma and chronic bronchitis. Salbutamol-d9 has been shown to have a pharmacokinetic profile that differs from that observed with the racemic mixture. The mass spectrometric detection method for this agent has been validated, and it was found to be suitable for use in human urine samples at concentrations up to 500 ng/mL. This agent binds to adrenergic receptors in muscle, bronchial tissue, and the lung, resulting in relaxation of smooth muscle and increased airway caliber.