CAS 1177-87-3: Acetato de dexametasona
Descripción:
Acetato de dexametasona es un corticosteroide sintético con propiedades antiinflamatorias e inmunosupresoras. Es un derivado de la dexametasona, caracterizado por la adición de un grupo acetato, que mejora su solubilidad y biodisponibilidad. Este compuesto se administra típicamente por inyección o como formulación oral y se utiliza para tratar una variedad de condiciones, incluidas alergias, trastornos autoinmunes y ciertos tipos de cáncer. Acetato de dexametasona actúa inhibiendo la liberación de mediadores inflamatorios y modulando la respuesta inmune. Tiene una vida media relativamente larga en comparación con otros corticosteroides, lo que permite una dosificación menos frecuente. La sustancia es conocida por su potencia y efectividad, pero también puede provocar efectos secundarios como el aumento de los niveles de azúcar en sangre, aumento de peso y posible supresión de la glándula adrenal con el uso prolongado. Al igual que con todos los corticosteroides, el monitoreo cuidadoso es esencial para mitigar los efectos adversos y garantizar la eficacia terapéutica.
Fórmula:C24H31FO6
InChI:InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
Clave InChI:InChIKey=AKUJBENLRBOFTD-RPRRAYFGSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C(CC3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@@H](C)[C@@]2(C(COC(C)=O)=O)O)[H]
Sinónimos:- (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
- (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Acetate
- (11β,16α)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
- (16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
- (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
- 16α-Methyl-9α-fluoroprednisolone 21-acetate
- Dalalone DP
- Dalalone LA
- Decadron LA
- Decadronal
- Dectancyl
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Dexamethasone acetate for peak identification CRS
CAS:Dexamethasone acetate for peak identification CRSFórmula:C24H31FO6Forma y color:Crystalline Powder. Whitish. Powder.Peso molecular:434.4977Dexamethasone Acetate
CAS:Producto controladoFórmula:C24H31FO6Forma y color:NeatPeso molecular:434.50Dexamethasone 21-Acetate
CAS:Fórmula:C24H31FO6Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:434.50Dexamethasone 21-acetate
CAS:Fórmula:C24H31FO6Pureza:(HPLC) ≥ 98.0%Forma y color:White to off-white crystalline powderPeso molecular:434.50Dexamethasone 21-acetate
CAS:Producto controladoFórmula:C24H31FO6Forma y color:NeatPeso molecular:434.50Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-
CAS:Fórmula:C24H31FO6Pureza:98%Forma y color:SolidPeso molecular:434.4977431999998Dexamethasone acetate
CAS:Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It is also used for replacement therapy in adrenal insufficiency and in a screening test for the diagnosis of cushing's syndrome. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C24H31FO6Peso molecular:434.5Dodecahydro-3H-cyclopenta2-oxoethyl Acetate Dexamethasone
CAS:Producto controladoFórmula:C24H31FO6Forma y color:NeatPeso molecular:434.5GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
CAS:Producto controlado- 105102-22-5
- 1177-87-3
- 124-94-7
- 13609-67-1
- 14484-47-0
- 1524-88-5
- 2135-17-3
- 2152-44-5
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- 3870-07-3
- 426-13-1
- 4419-39-0
- 50-02-2
- 50-03-3
- 50-04-4
- 50-23-7
- 50-24-8
- 51022-69-6
- 51333-22-3
- 514-36-3
- 53-06-5
- 53-36-1
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- 5593-20-4
- 57524-89-7
- 66734-13-2
- 67-78-7
- 73771-04-7
- 76-25-5
- 80474-14-2
- 83-43-2
- 987-24-6
Forma y color:Mixture21-O-Acetyl Dexamethasone-d5
CAS:Producto controladoApplications Isotope labelled intermediate in the synthesis of Dexamethasone (D298800), a glucocorticoid anti-inflammatory agent. References Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009), Rodgers, A., et al.: Chem. Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),Fórmula:C24D5H26FO6Forma y color:NeatPeso molecular:439.53Dexamethasone Acetate
CAS:Halogenated derivatives of adrenal cortical hormonesFórmula:C24H31FO6Forma y color:White PowderPeso molecular:434.2104721-O-Acetyl dexamethasone
CAS:Producto controlado21-O-Acetyl dexamethasone is a synthetic glucocorticoid that acts as a potent anti-inflammatory and immunosuppressive agent. It is used in the treatment of a wide range of conditions, including allergic reactions, skin disorders, and inflammatory bowel disease. The biological properties of this drug have been studied using an experimental model in rats. 21-O-Acetyl dexamethasone was found to be more effective than dexamethasone acetate in reducing allergic symptoms. The surface methodology has also been studied for the detection of this drug. This method is based on the reaction mechanism between the drug and matrix effect to produce fluorescent compounds that can be detected by ultraviolet (UV) light.Fórmula:C24H31FO6Pureza:Min. 95%Forma y color:White PowderPeso molecular:434.50 g/mol
