CAS 126-07-8: Griseofulvina
Descripción:
Griseofulvina es un medicamento antifúngico que se utiliza principalmente para tratar infecciones por dermatofitos, particularmente aquellas que afectan la piel, el cabello y las uñas. Se deriva del moho Penicillium griseofulvum y funciona inhibiendo la mitosis de las células fúngicas, evitando así el crecimiento y la reproducción de hongos. Griseofulvina se caracteriza por su estructura cristalina y se administra típicamente por vía oral. Es poco soluble en agua pero más soluble en disolventes orgánicos, lo que influye en su absorción y biodisponibilidad. La sustancia es conocida por su vida media relativamente larga, lo que permite una dosificación una vez al día en muchos casos. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales, dolor de cabeza y posibles reacciones alérgicas. Griseofulvina está contraindicado en ciertas poblaciones, como las personas embarazadas, debido a posibles efectos teratogénicos. Su efectividad a menudo se evalúa a través de la evaluación clínica y pruebas de laboratorio para confirmar la presencia de especies fúngicas susceptibles. En general, Griseofulvina sigue siendo una opción terapéutica significativa en el manejo de infecciones fúngicas específicas.
Fórmula:C17H17ClO6
InChI:InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
Clave InChI:InChIKey=DDUHZTYCFQRHIY-RBHXEPJQSA-N
SMILES:O=C1[C@@]2(OC=3C1=C(OC)C=C(OC)C3Cl)C(OC)=CC(=O)C[C@H]2C
Sinónimos:- (1′S,6′R)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
- (2R,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
- (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
- (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohexane]-3,4'-dione
- (2S,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
- 7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
- 7-Chloro-2',4,6-trimethoxy-6'β-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
- 7-Chloro-2′,4,6-trimethoxy-6′β-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
- 7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
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(+)-Griseofulvin, 97%
CAS:Griseofulvin is an antifungal drug. It is used both in animal and in humans, to treat ringworm infections of the skin and nails. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C17H19ClO6Pureza:97%Forma y color:White, PowderPeso molecular:354.78(+)-Griseofulvin
CAS:Fórmula:C17H17ClO6Pureza:>95.0%(HPLC)(qNMR)Forma y color:White to Almost white powder to crystalPeso molecular:352.77(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
CAS:Pureza:98.0%Forma y color:SolidPeso molecular:352.7699890136719Griseofulvin
CAS:Antibiotics nesoiFórmula:C17H17ClO6Forma y color:White Cream PowderPeso molecular:352.07137Griseofulvin
CAS:Fórmula:C17H17ClO6Pureza:97.0 - 102.0 % (dried basis)Forma y color:White or off-white powderPeso molecular:352.77Griseofulvin
CAS:GriseofulvinFórmula:C17H17ClO6Pureza:99.8% / 98.3%Forma y color:WhitePeso molecular:352.07137Griseofulvin Permeability Diameter
CAS:Antibiotics nesoiFórmula:C17H17ClO6Forma y color:White Off-White PowderPeso molecular:352.77Griseofulvin-13C-d3
CAS:Fórmula:C1613CH14D3ClO6Forma y color:White To Off-White SolidPeso molecular:356.78Griseofulvin
CAS:Griseofulvin (Fulvicin) is an antifungal agent used in the treatment of TINEA infections.Fórmula:C17H17ClO6Pureza:95.83% - 98.12%Forma y color:Stout Octahedra Or Rhombs From BenzenePeso molecular:352.77Griseofulvin - Bio-X ™
CAS:Griseofulvin is an antifungal drug used to treat several types of dermatophytosis (ringworm). This includes fungal infections of the nails, scalp and the skin when antifungal creams have not worked. It is suggested that it prevents nuclear acid production and fungal cell mitosis. Additionally, through binding to alpha and beta tubulin, it interferes with the function of the spindle and cytoplasmic microtubules. Griseofulvin is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C17H17ClO6Pureza:Min. 95%Forma y color:PowderPeso molecular:352.77 g/molGriseofulvin 100 µg/mL in Acetonitrile
CAS:Fórmula:C17H17ClO6Forma y color:Single SolutionPeso molecular:352.77Griseofulvin
CAS:Producto controladoApplications It is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum.Environmental contaminants; Food contaminants References Oxford, et al.: Biochem. J., 33, 240 (1939), Townley, E.R., et al.: Anal. Profiles Drug Subs., 8, 219 (1979),Fórmula:C17H17ClO6Forma y color:Off-WhitePeso molecular:352.77Griseofulvin
CAS:Anti-fungal; microtubule polymerization inhibitorFórmula:C17H17ClO6Pureza:Min. 97 Area-%Forma y color:PowderPeso molecular:352.77 g/mol
![(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-d…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF354301.jpg&w=3840&q=75)
