CAS 12650-69-0: Mupirocina
Descripción:
Mupirocina es un antibiótico tópico que se utiliza principalmente para el tratamiento de infecciones cutáneas causadas por ciertas bacterias, particularmente Staphylococcus aureus, incluidas las cepas resistentes a meticilina (MRSA). Se deriva de la fermentación de la bacteria Pseudomonas fluorescens. Mupirocina funciona inhibiendo la síntesis de proteínas bacterianas al unirse a la isoleucil-tRNA sintetasa, lo que interrumpe la incorporación de isoleucina en las proteínas, lo que finalmente conduce a la muerte celular bacteriana. La sustancia generalmente está disponible en forma de ungüento o crema y se aplica directamente en el área afectada. Mupirocina es conocido por su baja absorción sistémica cuando se usa tópicamente, lo que lo hace efectivo para infecciones localizadas con un riesgo mínimo de efectos secundarios sistémicos. Generalmente es bien tolerado, aunque algunos pacientes pueden experimentar irritación local o reacciones alérgicas. Debido a su mecanismo de acción específico y su efectividad contra cepas resistentes, Mupirocina es una opción importante en el manejo de infecciones cutáneas y se utiliza a menudo en entornos ambulatorios y hospitalarios.
Fórmula:C26H44O9
InChI:InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1
Clave InChI:InChIKey=MINDHVHHQZYEEK-HBBNESRFSA-N
SMILES:C([C@H]1[C@]([C@H]([C@H](C)O)C)(O1)[H])[C@@H]2[C@@H](O)[C@@H](O)[C@H](C/C(=C/C(OCCCCCCCCC(O)=O)=O)/C)OC2
Sinónimos:- (E)-(2S,3R,4R,5S)-5-((2S,3S,4S,5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl)tetrahydro-3,4-dihydroxy-beta-methyl-2H-pyran-2-crotonic acid, ester with 9-hydroxynonanoic acid
- 8-Carboxyoctyl (E)-4-(2S,3R,4R,5S)-5-((2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl)-3,4-dihydroxytetrahydro-2H-pyran-2-yl)-3-methylcrotonat
- 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoic acid (non-preferred name)
- <span class="text-smallcaps">L</span>-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
- <span class="text-smallcaps">L</span>-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, [2E,8[2S,3S(1S,2S)]]-
- Bactoderm
- Bactroban
- Bactroban Ointment
- Brl 4910A
- Centany
- L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
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Encontrado 15 productos.
Mupirocin, 92%
CAS:Mupirocin is involved in inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. It also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C26H44O9Pureza:92%Peso molecular:500.63Mupirocin
CAS:Fórmula:C26H44O9Pureza:920 - 1020 μg/mg (anhydrous)Forma y color:White to off-white powderPeso molecular:500.63Mupirocin
CAS:Producto controladoApplications Mupirocin, is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. Topical antibacterial. References Hughes, J., et al.: J. Antibiot., 31, 330 (1978), Ward, A., et al.: Drugs, 32, 425 (1986), Casewell, M.W., et al.: J. Antimicrob. Chemother., 19, 1 (1987),Fórmula:C26H44O9Forma y color:White To Off-WhitePeso molecular:500.62Mupirocin
CAS:Fórmula:C26H44O9Pureza:>98.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:500.63L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
CAS:Fórmula:C26H44O9Pureza:95%Forma y color:SolidPeso molecular:500.6222Mupirocin
CAS:Inhibitor of isoleucyl-tRNA synthetase; inhibitor of protein synthesisFórmula:C26H44O9Pureza:Min. 92 Area-%Forma y color:White PowderPeso molecular:500.62 g/molMupirocin
CAS:Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci.Fórmula:C26H44O9Pureza:97.37% - 98.33%Forma y color:SolidPeso molecular:500.62
