CAS 130-61-0: Clorhidrato de tioridazina
Descripción:
Clorhidrato de tioridazina es un medicamento antipsicótico que se utiliza principalmente para tratar la esquizofrenia y otros trastornos psicóticos. Pertenece a la clase de compuestos fenotiazínicos, que se caracterizan por una estructura de tres anillos que incluye un átomo de azufre. La tioridazina actúa principalmente como un antagonista de la dopamina, bloqueando los receptores de dopamina en el cerebro, lo que ayuda a aliviar los síntomas de la psicosis. La forma de sal hidrocloruro mejora su solubilidad y estabilidad. En términos de características físicas, Clorhidrato de tioridazina es típicamente un polvo cristalino blanco a blanco sucio. Es soluble en agua y alcohol, con un punto de fusión relativamente bajo. El compuesto puede presentar efectos secundarios, incluyendo sedación, efectos anticolinérgicos y posibles problemas cardiovasculares, lo que requiere un monitoreo cuidadoso durante el tratamiento. Además, la tioridazina se ha asociado con un riesgo de prolongación del QT, lo que puede llevar a alteraciones graves del ritmo cardíaco. Al igual que con cualquier medicamento, es esencial usar Clorhidrato de tioridazina bajo la guía de un profesional de la salud, considerando sus beneficios terapéuticos y riesgos potenciales.
Fórmula:C21H26N2S2·ClH
InChI:InChI=1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
Clave InChI:InChIKey=NZFNXWQNBYZDAQ-UHFFFAOYSA-N
SMILES:C(CC1N(C)CCCC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(SC)C3.Cl
Sinónimos:- 10-(2-(1-Methyl-2-Piperidinyl)Ethyl)-2-(Methylthio)-10H-Phenothiazinmono
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)-Ethyl]-2-[Methylthiol]-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)Ethyl]-2-(Methylthio)-10H-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
- 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
- 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride (1:1)
- 10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride
- 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
- 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, hydrochloride (1:1)
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Encontrado 19 productos.
THIORIDAZINE HYDROCHLORIDE CRS
CAS:THIORIDAZINE HYDROCHLORIDE CRSFórmula:C21H27ClN2S2Forma y color:PowderPeso molecular:407.0355Thioridazine hydrochloride
CAS:Fórmula:C21H26N2S2·HClPureza:≥ 98.0%Forma y color:White to off-white powder or crystalsPeso molecular:407.03Thioridazine HCl
CAS:Fórmula:C21H26N2S2·HClForma y color:White To Off-White SolidPeso molecular:370.58 36.46Thioridazine Hydrochloride
CAS:Fórmula:C21H26N2S2·HClPureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:407.03Thioridazine Hydrochloride
CAS:Producto controladoFórmula:C21H26N2S2·ClHForma y color:NeatPeso molecular:407.04Thioridazine Hydrochloride
CAS:Antidepressants, tranquilizers and other pschotherapeutic agentsFórmula:C21H26N2S2·ClHForma y color:PowderPeso molecular:406.1304210-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
CAS:10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochlorideFórmula:C21H26N2S2·ClHPureza:98%Forma y color: white solidPeso molecular:407.04g/molThioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Fórmula:C21H27ClN2S2Pureza:99.55% - 99.55%Forma y color:White To Off-White SolidPeso molecular:407.04Thioridazine hydrochloride
CAS:Producto controladoFórmula:C21H26N2S2·ClHForma y color:NeatPeso molecular:407.0410-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride
CAS:Producto controladoThe drug, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride (CGP 46660), is a competitive antagonist at the human histamine H3 receptor. It has been shown to bind to the histamine H3 receptor in the range of 0.001 to 1 μM and is selective for this receptor over other receptors. CGP 46660 is an optical sensor that can be used in titration calorimetry experiments to measure changes in heat production when it binds to histamine H3 receptors. The drug also has been shown to inhibit guanine nucleotide-binding protein (G protein) signaling pathways and brain functions such as memory formation, learning, and attention span. These effects were demonstrated in humans by measuring EEG activity. The optimum concentration of CGP 46660 for these effects was found to be between 0.01 and 10 μM.Fórmula:C21H27ClN2S2Pureza:Min. 95%Forma y color:PowderPeso molecular:407.04 g/molThioridazine Hydrochloride
CAS:Producto controladoApplications Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. This compound has been reported to bind strongly to dopamine receptors on cancer stem cells and cause differentiation leaving normal cells alone (see Can. Chem. News 12 July/August 2012). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),Fórmula:C21H26N2S2·ClHForma y color:Light YellowPeso molecular:407.04
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