CAS: 1346747-14-5

Moxifloxacin is a synthetic broad-spectrum antibiotic, which is derived from the fluoroquinolones class. It functions by inhibiting bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes critical for DNA replication, transcription, repair, and recombination. The inhibition of these enzymes results in DNA breakage, thereby leading to bacterial cell death. Moxifloxacin exhibits potent activity against a wide variety of Gram-positive and Gram-negative organisms. It is particularly effective against respiratory pathogens, including multidrug-resistant Streptococcus pneumoniae. Additionally, this compound is utilized in the treatment of bacterial skin infections, complicated intra-abdominal infections, and acute bacterial sinusitis, among others. Due to its robust ability to penetrate tissues and its broad-spectrum efficacy, moxifloxacin is a valuable pharmacological option in the management of severe bacterial infections, where resistant organisms are of clinical concern.