CAS 1405-89-6: Bacitracina zinc
Descripción:
Bacitracina zinc es un compuesto antibiótico que es una mezcla compleja de polipéptidos cíclicos producidos por la bacteria Bacillus subtilis. Se utiliza principalmente por sus propiedades antibacterianas, particularmente contra bacterias Gram-positivas. La forma de sal de zinc mejora su estabilidad y solubilidad, lo que lo hace adecuado para diversas aplicaciones, incluidas pomadas tópicas y medicina veterinaria. Bacitracina zinc actúa inhibiendo la síntesis de la pared celular bacteriana, lo que finalmente conduce a la lisis celular y la muerte. A menudo se utiliza en combinación con otros antibióticos para ampliar su espectro de actividad. El compuesto se considera generalmente seguro para uso tópico, pero puede causar reacciones alérgicas en algunas personas. En términos de propiedades físicas, Bacitracina zinc es típicamente un polvo blanco a blanco sucio que es soluble en agua y tiene un sabor ligeramente amargo. Su uso está regulado, y es importante seguir las pautas para prevenir el desarrollo de resistencia a los antibióticos.
Fórmula:Unspecified
InChI:InChI=1/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-;/m0./s1
SMILES:CCC(C)C(C1=NC(CS1)C(=NC(CC(C)C)C(=NC(CCC(=O)O)C(=NC(C(C)CC)C(=NC1CCCCN=C(C(CC(=N)O)N=C(C(CC(=O)O)N=C(C(Cc2cnc[nH]2)N=C(C(Cc2ccccc2)N=C(C(C(C)CC)N=C(C(CCCN)N=C1O)O)O)O)O)O)O)O)O)O)O)N.[Zn]
Sinónimos:- Albac
- Bacifarmin
- Bacifarmin-zinc
- Baciferm
- Baciferm PB
- Bacitracin Zinc
- Bacitracin zinc salt
- L-isoleucinamide, N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-alpha-glutamyl-N-[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-15-(1-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-12-(phenylmethyl)-1,4,7,10,13,16,19-heptaazacyclopentacos-21-yl]-, zinc salt (1:1)
- Noptracin
- St 56
- zinc N-{[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazol-4-yl]carbonyl}-L-leucyl-5-oxidanidyl-5-oxidanylidene-D-norvalyl-N-{(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-6-(carboxylatomethyl)-9-(1H-imidazol-5-ylmethyl)-15-[(1S)-1-methylpropyl]-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl}-L-isoleucinamide
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Encontrado 10 productos.
Bacitracin for system suitability CRS
CAS:Bacitracin for system suitability CRSFórmula:C66H103N17O16SZnForma y color:White. Yellow. Powder.Peso molecular:1488.101BACITRACIN ZINC CRS
CAS:BACITRACIN ZINC CRSFórmula:C66H103N17O16SZnForma y color:White. Yellow. Powder.Peso molecular:1488.101Bacitracin zinc
CAS:Bacitracin zinc is a biocide that is used for the treatment of infectious diseases in animals. It has neurotrophic and polyvinyl pyrrolidone properties, which inhibit bacterial growth by preventing protein synthesis. Bacitracin zinc can be used to treat infections caused by bacteria that are resistant to penicillin, tetracycline, erythromycin, and other antibiotics. This drug can be formulated as a suspension or an emulsion in a polymeric matrix with undamaged polymer chains to provide stabilization against hydrolysis.Fórmula:C66H101N17O16SZnPureza:Min. 95%Forma y color:PowderPeso molecular:1,486.06 g/molBacitracin Zinc
CAS:Bacitracin Zinc is a dephosphorylated disruptor of C55-isoprene pyrophosphate that inhibits Tyr cleavage in Met-enkephalin with an IC50 of 10 μM.Fórmula:C66H101N17O16SZnPureza:63.98%Forma y color:Light-Colored Free-Flowing PowdersPeso molecular:1486.07Bacitracin zinc salt
CAS:Fórmula:C66H101N17O16SZnPureza:≥ 65.0U/mg (dried basis)Forma y color:Off-white to light-yellow powderPeso molecular:1486.07Bacitracin, zinc salt, potency min. 60 Units/mg
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Forma y color:Powder, White to yellow to beige to light greyBacitracin Zinc
CAS:Antibiotics nesoiFórmula:C66H101N17O16SZn(BacitracinAZinc)C65H99N17O16SZn(BacitracinB1B2orB3Zinc)Forma y color:White Tan Light Brown PowderPeso molecular:1483.66243Bacitracin Zinc (>80%)
CAS:Producto controladoApplications Bacitracin is a peptide antibiotic effective against gram-postive bacteria. Bacitracin is an inhibitor of peptidoglycan synthesis. Bacitracin disrupts bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate. Bacitracin also strongly inhibits proline endopeptidase from human muscle. References Ward, J.B. et al.: Biochem. J., 141, 227 (1974); Anastasi, A. et al.: Biochem. J., 290, 601 (1993); Daly, D.J. et al.: Biochem. Soc. Trans., 13, 1161 (1985); Weinberg, E.D. et al.: Antibiot. Ber., 90, (1967);Fórmula:C65H99N17O16S·ZnPureza:>80%Forma y color:Light Yellow To Off-WhitePeso molecular:1472.06
