CAS 143491-57-0: emtricitabina
Descripción:
emtricitabina es un medicamento antirretroviral que se utiliza principalmente en el tratamiento de la infección por VIH. Pertenece a la clase de fármacos conocidos como inhibidores de la transcriptasa inversa de nucleósidos (ITIN). La fórmula química de emtricitabina es C₁₃H₁₅N₃O₃S, y presenta un anillo de tiofeno, que contribuye a sus propiedades únicas. emtricitabina se caracteriza por su capacidad para inhibir la enzima transcriptasa inversa, evitando así la replicación del virus. Se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal. El medicamento es conocido por su favorable perfil farmacocinético, que incluye una larga vida media, lo que permite una dosificación una vez al día. emtricitabina se utiliza a menudo en combinación con otros agentes antirretrovirales para mejorar la eficacia y reducir el riesgo de resistencia. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales y erupciones cutáneas, pero generalmente es bien tolerado. Su efectividad y perfil de seguridad lo han convertido en un componente clave en los regímenes de tratamiento del VIH en todo el mundo.
Fórmula:C8H10FN3O3S
InChI:InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1
Clave InChI:InChIKey=XQSPYNMVSIKCOC-NTSWFWBYSA-N
SMILES:O=C1N([C@H]2O[C@@H](CO)SC2)C=C(F)C(N)=N1
Sinónimos:- (-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
- (-)-2'-Deoxy-5-fluoro-3'-thiacytidine
- (-)-2′,3′-Dideoxy-5-fluoro-3′-thiacytidine
- (-)-Beta-2',3'-Dideoxy-5-Fluoro-3'-Thiacytidine
- (-)-Ftc
- 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.
- 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
- 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-5-oxathiolanyl]-
- 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)-
- 4-Amino-5-Fluoro-1-(2-(Hydroxymethyl)-1,3-Oxathiolan-5-Yl)-(2R-Cis)-2(1H)-Pyrimidinone
- 4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
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Emtricitabine
CAS:Applications A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500). References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)Fórmula:C8H10FN3O3SForma y color:Light YellowPeso molecular:247.25Emtricitabine (1.0 mg/mL in Methanol)
CAS:Fórmula:C8H10FN3O3SForma y color:ColourlessPeso molecular:247.25Emtricitabine
CAS:Emtricitabine is a nucleoside reverse transcriptase inhibitor with anti-human immunodeficiency virus (HIV) and hepatitis B virus activity.Cost-effective and quality-assured.Fórmula:C8H10FN3O3SPureza:100% - 99.78%Forma y color:White PowderPeso molecular:247.25Emtricitabine
CAS:Fórmula:C8H10FN3O3SPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:247.242',3'-Dideoxy-5-fluoro-3'-thiacytidine
CAS:Emtricitabine is a nucleoside analog that is an antiviral drug used to treat HIV/AIDS. It is a synthetic nucleoside analog of cytidine, in which the 3' phosphate and 5' hydroxyl groups have been replaced with a fluorine atom and a methoxy group, respectively. Emtricitabine has been shown to inhibit the synthesis of viral DNA by competing for incorporation into the viral DNA strand during the elongation phase of viral replication. Emtricitabine also has anticancer activity, but no other known therapeutic uses.Fórmula:C8H10FN3O3SPureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:247.25 g/molEmtricitabine Phosphonic Acid Triethylammonium Salt
CAS:Producto controladoApplications (-)-Emtricitabine (E525000) derivative.Fórmula:C8H10FN3O5PS·C6H13NForma y color:NeatPeso molecular:409.3934-Amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:247.24000549316406Emtricitabine
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C8H10FN3O3SForma y color:White Off-White Crystalline PowderPeso molecular:247.04269Emtricitabine-d2,15N
CAS:Emtricitabine-d2,15N is a labelled version of emtricitabine. It is a nucleoside reverse transcriptase inhibitor that inhibits the HIV-1 virus by blocking the activity of the enzyme needed to convert RNA into DNA. This drug also offers long-term efficacy and can be used in combination with other antiretroviral agents including tenofovir alafenamide hemifumarate (TAF) and tenofovir disoproxil fumarate (TDF). The addition of TAF or TDF to emtricitabine-d2,15N provides an active antiretroviral therapy for HIV/AIDS patients. Emtricitabine-d2,15N has shown to reduce viral load significantly in people taking it as part of their treatment regimen.Fórmula:C8D10FN3O3SPureza:Min. 95%Peso molecular:257.3 g/molEmtricitabine 100 µg/mL in Acetonitrile
CAS:Fórmula:C8H10FN3O3SForma y color:Single SolutionPeso molecular:247.25Emtricitabine - Bio-X ™
CAS:Emtricitabine is an antiviral drug that is used to treat chronic viral hepatitis, which is caused by the hepatitis B and C viruses. The drug blocks the activity of reverse transcriptase, which is an enzyme necessary for the replication of viral RNA in the body. Emtricitabine has been shown to be effective against acute hepatitis B virus infection and chronic hepatitis B virus infection with or without cirrhosis. It also has been shown to be effective against chronic hepatitis C virus infection with or without cirrhosis. Emtricitabine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C8H10FN3O3SPureza:Min. 95%Forma y color:White/Off-White SolidPeso molecular:247.25 g/molEmtricitabine-d2,15N
CAS:Producto controladoFórmula:C8D2H8F15NN2O3SForma y color:NeatPeso molecular:250.252Emtricitabine System Suitability Mixture A (Emtricitabine; 5-epi Emtricitabine)
CAS:Producto controladoFórmula:MixtureVisitourWebsiteForma y color:MixturePeso molecular:Mixture - Visit our Website
