CAS 144060-53-7: Febuxostat
Descripción:
Febuxostat es un inhibidor de la xantina oxidasa utilizado principalmente en el manejo de la hiperuricemia asociada con la gota. Se caracteriza por su capacidad para reducir los niveles de ácido úrico en la sangre al inhibir la enzima responsable de la producción de ácido úrico. La fórmula química de Febuxostat refleja su estructura compleja, que incluye un anillo de pirimidina y varios grupos funcionales que contribuyen a su actividad farmacológica. Se administra típicamente por vía oral y tiene una vida media relativamente larga, lo que permite una dosificación una vez al día. Febuxostat es conocido por su eficacia en la reducción de los niveles de ácido úrico en comparación con el alopurinol, otro tratamiento común para la gota, y a menudo se prescribe para pacientes que son intolerantes al alopurinol o para quienes este es ineficaz. La sustancia generalmente es bien tolerada, aunque puede tener efectos secundarios, incluyendo elevaciones de enzimas hepáticas y trastornos gastrointestinales. Al igual que con cualquier medicamento, el monitoreo y la consulta con un proveedor de atención médica son esenciales para garantizar un uso seguro y efectivo.
Fórmula:C16H16N2O3S
InChI:InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
Clave InChI:InChIKey=BQSJTQLCZDPROO-UHFFFAOYSA-N
SMILES:C(O)(=O)C=1SC(=NC1C)C2=CC(C#N)=C(OCC(C)C)C=C2
Sinónimos:- 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid
- 2-[3-Cyano-4-(2-Methylpropoxy)Phenyl]-4-Methylthiazole-5-Carboxylic Acid
- 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
- 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid
- 2-[3-Cyano-4-isobutoxyphenyl]-4-methylthiazole-5-carboxylic acid
- 5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-
- Adenuric
- Febugood
- Feburic
- Febutaz
- Febuxostat (Polymorphs)
- Ver más sinónimos
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Encontrado 16 productos.
2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
CAS:Pureza:95.0%Peso molecular:316.3800048828125Febuxostat
CAS:Fórmula:C16H16N2O3SPureza:>97.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:316.38Febuxostat
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFórmula:C16H16N2O3SForma y color:White Off-White PowderPeso molecular:316.08816Febuxostat
CAS:Febuxostat (TEI 6720) is a xanthine oxidase Inhibitor.Fórmula:C16H16N2O3SPureza:99.80%Forma y color:Crystalline SolidPeso molecular:316.37Ref: TM-T0773
5mg38,00€10mg57,00€25mg88,00€50mg105,00€100mg133,00€200mg188,00€500mg321,00€1mL*10mM (DMSO)59,00€Febuxostat
CAS:Fórmula:C16H16N2O3SPureza:(HPLC) ≥ 98.0%Forma y color:White to off-white crystalline powderPeso molecular:316.37Febuxostat
CAS:Non-purine inhibitor of xanthine oxidaseFórmula:C16H16N2O3SPureza:Min. 95%Forma y color:White PowderPeso molecular:316.38 g/mol2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
CAS:Fórmula:C16H16N2O3SPureza:98%Forma y color:SolidPeso molecular:316.3748Febuxostat - Bio-X ™
CAS:Febuxostat is a non-purine xanthine oxidase inhibitor that is used for the treatment and management of hyperuricemia and chronic gouty arthritis. Febuxostat inhibits the uptake of uric acid from the blood into cells and thereby reduces its concentration in plasma. Additionally, this drug has been shown to have anti-inflammatory and antioxidant effects. Febuxostat is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C16H16N2O3SPureza:Min. 95%Forma y color:PowderPeso molecular:316.38 g/molFebuxostat, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C16H16N2O3SPureza:98%Forma y color:White to almost white, PowderPeso molecular:316.38Febuxostat
CAS:Applications Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout. References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),Fórmula:C16H16N2O3SForma y color:White To Off-WhitePeso molecular:316.37
