CAS 14605-22-2: Ácido tauroursodesoxicólico
Descripción:
Ácido tauroursodesoxicólico (TUDCA) es un derivado de ácido biliar que desempeña un papel significativo en varios procesos biológicos. Es una forma conjugada de taurina del ácido ursodeoxicólico, conocido por sus propiedades citoprotectoras. TUDCA se caracteriza por su naturaleza hidrofílica, que mejora su solubilidad en agua en comparación con otros ácidos biliares. Este compuesto está principalmente involucrado en la regulación del flujo biliar y se ha estudiado por sus posibles efectos terapéuticos en enfermedades hepáticas, trastornos neurodegenerativos y síndromes metabólicos. Se cree que TUDCA ejerce sus efectos beneficiosos a través de mecanismos como la actividad antiapoptótica, la modulación del estrés del retículo endoplásmico y la mejora de la función mitocondrial. Además, se ha investigado su papel en la promoción de la sensibilidad a la insulina y la reducción de la inflamación. TUDCA se administra típicamente en un entorno clínico o como un suplemento dietético, y su perfil de seguridad es generalmente favorable, aunque se están realizando más investigaciones para esclarecer completamente sus mecanismos y potencial terapéutico.
Fórmula:C26H45NO6S
InChI:InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-/m1/s1
Clave InChI:InChIKey=BHTRKEVKTKCXOH-LBSADWJPSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCCS(=O)(=O)O)=O)C)[H])[H]
Sinónimos:- 2-(3Α,7Β-Dihydroxy-5Β-Cholan-24-Amido)Ethanesulfonic Acid
- 2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic acid
- 2-{[(3Alpha,5Beta,7Beta)-3,7-Dihydroxy-24-Oxocholan-24-Yl]Amino}Ethanesulfonic Acid
- 2-{[(3Alpha,5Beta,7Beta,8Xi,9Xi,14Xi)-3,7-Dihydroxy-24-Oxocholan-24-Yl]Amino}Ethanesulfonic Acid
- 3α,7β-Dihydroxy-5β-cholanoyltaurine
- 9,10-Secocholesta-5,7,10-Trien-3-Ol
- Cholane, ethanesulfonic acid deriv.
- Ethanesulfonic acid, 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
- Taurine, N-(3α,7β-dihydroxy-5β-cholan-24-oyl)-
- Taurolite
- Taurursodiol
- Ver más sinónimos
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Encontrado 13 productos.
Ursodoxicoltaurine for impurity B identification CRS
CAS:Ursodoxicoltaurine for impurity B identification CRSTauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Fórmula:C26H45NO6SPureza:98.12% - 99.93%Forma y color:White SolidPeso molecular:499.7Sodium tauroursodeoxycholate
CAS:Fórmula:C26H44NO6SNa·xH2OPureza:≥ 97.0% (dried basis)Forma y color:White or almost white powderPeso molecular:521.69 (anhydrous)Tauroursodeoxycholic Acid
CAS:Stability Hygroscopic Applications TAUROURSODEOXYCHOLIC ACID (cas# 14605-22-2) is a useful research chemical.Fórmula:C26H45NO6SForma y color:Off-WhitePeso molecular:499.70Tauroursodeoxycholic Acid Dihydrate
CAS:Fórmula:C26H45NO6S·2H2OPureza:>98.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:535.74Tauroursodeoxycholic Acid-d4 (Tauroursodiol-d4)
CAS:Fórmula:C26H41D4NO6SForma y color:White To Off-White SolidPeso molecular:503.73Ethanesulfonic acid,2-[[(3a,5b,7b)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
CAS:Fórmula:C26H45NO6SPureza:98%Forma y color:SolidPeso molecular:499.7036Tauro-d4-ursodeoxycholic Acid
CAS:Producto controladoApplications Tauro-d4-ursodeoxycholic Acid is a useful isotopically labeled compound of Tauroursodeoxycholic Acid (T779310). It is used in studying regaining functionality capacity for stem cell or fibroblast cell and functional lines used in cellular therapy. References Teker, Hikmet Taner, et al.: Turk. Pat. Appl., (2019);Fórmula:C26H41D4NO6SForma y color:Off-WhitePeso molecular:503.73Tauroursodeoxycholic Acid (TUDCA)
CAS:Fórmula:C26H45NO6SForma y color:White To Off-White SolidPeso molecular:499.71Tauroursodeoxycholic acid
CAS:Tauroursodeoxycholic acid (TUDCA) is a bile acid derivative, which is synthesized endogenously in the human body as a liver metabolite. It originates from the conjugation of ursodeoxycholic acid (UDCA) with taurine, which enhances its solubility and biological activity. TUDCA functions primarily by inhibiting apoptosis and reducing endoplasmic reticulum stress within cells. It achieves this by mitigating the accumulation of misfolded proteins and enhancing proper protein folding, thereby maintaining cellular homeostasis. Taurioursodeoxycholic acid is commonly employed in research focused on hepatoprotection, as it has demonstrated efficacy in ameliorating liver conditions such as cholestasis. Furthermore, its applications extend to studies on neurodegenerative diseases due to its cytoprotective properties, which help prevent neuronal cell death. With its broad spectrum of potential therapeutic benefits, TUDCA continues to be an area of significant interest in both basic and applied biomedical sciences.Fórmula:C26H45NO6SPureza:Min. 95%Forma y color:PowderPeso molecular:499.7 g/mol
![Ethanesulfonic acid,2-[[(3a,5b,7b)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00HXH5.jpg&w=3840&q=75)
