CAS 15663-27-1: Cisplatino
Descripción:
Cisplatino, con el número CAS 15663-27-1, es un fármaco de quimioterapia a base de platino ampliamente utilizado en el tratamiento de varios tipos de cáncer, incluidos el cáncer testicular, de ovario, de vejiga y de pulmón. Su fórmula química es cis-[Pt(NH3)2Cl2], lo que indica que consiste en un átomo de platino coordinado a dos moléculas de amoníaco y dos iones de cloruro. El compuesto se caracteriza por su geometría cuadrada plana, que es crucial para su actividad biológica. Cisplatino funciona principalmente formando enlaces cruzados en el ADN, inhibiendo así la replicación y transcripción del ADN, lo que lleva a la apoptosis en células cancerosas que se dividen rápidamente. Se administra típicamente por vía intravenosa y puede tener efectos secundarios como nefrotoxicidad, náuseas y mielosupresión. La efectividad del fármaco puede verse influenciada por factores como la presencia de proteínas celulares específicas y el microambiente tumoral. Debido a su mecanismo de acción, Cisplatino a menudo se utiliza en combinación con otros agentes quimioterapéuticos para mejorar la eficacia terapéutica y superar la resistencia.
Fórmula:Cl2H6N2Pt
InChI:InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
Clave InChI:InChIKey=LXZZYRPGZAFOLE-UHFFFAOYSA-L
SMILES:[Pt+2]([Cl-])([Cl-])([NH3])[NH3]
Sinónimos:- (SP-4-2)-Diamminedichloroplatinum
- Abiplatin
- Biocisplatinum
- Briplatin
- CP Ethypharm
- Cacp
- Cddp
- Cis-Platinum(Ii)Diammine Dichloride
- Cismaplat
- Cisplatin
- Cisplatine
- Ver más sinónimos
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Cisplatin
CAS:Inorganic or organic compounds of precious metals, whether or not chemically defined; amalgrams of precious metals, nesoiFórmula:Cl2H6N2PtForma y color:Yellow Orange PowderPeso molecular:298.9556Cisplatin, USP grade
CAS:Fórmula:Cl2H6N2PtPureza:≥ 4.5Forma y color:Yellow to orange powderPeso molecular:300.06cis-Dichlorodiammineplatinum (II), CISPLATIN (USP)
CAS:cis-Dichlorodiammineplatinum (II), CISPLATIN (USP)Fórmula:cisPt(NH3)2Cl2Forma y color:yellow to orange xtl.Peso molecular:300.06cis-Diammineplatinum(II) Dichloride
CAS:Fórmula:H6Cl2N2PtForma y color:Light orange to Yellow to Green powder to crystalPeso molecular:300.05Cisplatin
CAS:Cisplatin is a chemotherapeutic drug that inhibits the growth of cancer cells by binding to DNA. It binds to DNA and inhibits transcription and replication, leading to the accumulation of p-glycoprotein (P-gp) inhibitor in the cell membrane, which prevents the efflux of intracellular caspase activators. This leads to an increase in apoptosis among cancer cells and a decrease in healthy tissue. The toxicology of cisplatin has been studied extensively, with low-dose groups showing no signs of toxicity.Fórmula:Cl2H6N2PtPureza:(Hplc) 98 To 102%Forma y color:Yellow PowderPeso molecular:300.05 g/molcis-Dichlorodiamineplatinum(II), 99.99%, (trace metal basis)
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:Cl2H6N2PtPureza:99.99%Forma y color:Yellow to orange, Powder or crystalsPeso molecular:300.04cis-Diamminedichloroplatinum(II), Pt 64.5% min
CAS:Being a potent anticancer agent that blocks DNA synthesis, the pharmaceutical compositions are used in chemotherapy. First member of platinum-containing anti-cancer drugs. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:Cl2H6N2PtPureza:64.5%Peso molecular:300.04cis-Dichlorodiammine platinum(II), 99% CISPLATIN
CAS:cis-Dichlorodiammine platinum(II), 99% CISPLATINFórmula:cisPt(NH3)2Cl2Pureza:99%Forma y color:yellow to orange xtl.Peso molecular:300.06cis-Diammineplatinum(II) dichloride
CAS:Fórmula:Cl2H6N2PtPureza:99%Forma y color:SolidPeso molecular:300.045Cisplatin - Bio-X ™
CAS:Cisplatin, also known as cisplatinum, is a platinum-based anti-cancer agent that inhibits the EGFR, which is a receptor tyrosine kinase. It has been shown to have anti-cancer effects in melanoma cells and to inhibit tumor growth in mice. Cisplatin acts by interfering with the mechanism of DNA repairing. It loses one chloride ligand and binds to DNA to inhibit the synthesis, causing DNA damage, and thus inducing apoptosis in cancer cells. In certain studies, the use of cisplatin in combination with other metal chelators has shown improvement in the uptake of the anticancer drug. CisplatiN - Bio-X™ is part of our Bio-X™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:Cl2H6N2PtPureza:Min. 99%Forma y color:PowderPeso molecular:300.05 g/molCisplatin
CAS:Fórmula:Cl2H6N2PtPureza:≥ 98.0% (anhydrous)Forma y color:Yellow to orange powderPeso molecular:300.06Cisplatin
CAS:Cisplatin (CDDP) is a DNA cross-linking agent.Fórmula:Cl2H6N2PtPureza:97.13% - 99.63%Forma y color:Orange-Yellow To Deep Yellow Solid Or PowderPeso molecular:300.04
