CAS 192725-17-0: Lopinavir
Descripción:
Lopinavir es un medicamento antirretroviral utilizado principalmente en el tratamiento del VIH/SIDA. Pertenece a la clase de inhibidores de la proteasa y a menudo se combina con ritonavir para mejorar su eficacia y biodisponibilidad. La fórmula química de Lopinavir es C37H48N4O5, y tiene un peso molecular de aproximadamente 628.88 g/mol. Lopinavir se caracteriza por su estructura compleja, que incluye múltiples anillos y grupos funcionales que contribuyen a su actividad farmacológica. Se administra típicamente por vía oral en forma de tabletas o solución líquida. La sustancia es conocida por su capacidad para inhibir la enzima proteasa del VIH, evitando así la replicación viral. Lopinavir generalmente es bien tolerado, pero puede tener efectos secundarios, incluidos trastornos gastrointestinales y posibles impactos en el metabolismo de lípidos. Debido a su papel en el tratamiento del VIH, Lopinavir a menudo forma parte de regímenes de terapia combinada, que pueden incluir otros agentes antirretrovirales para mejorar los resultados del tratamiento y reducir el riesgo de resistencia.
Fórmula:C37H48N4O5
InChI:InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
Clave InChI:InChIKey=KJHKTHWMRKYKJE-SUGCFTRWSA-N
SMILES:[C@@H](C(N[C@@H](CC1=CC=CC=C1)C[C@@H]([C@H](CC2=CC=CC=C2)NC(COC3=C(C)C=CC=C3C)=O)O)=O)([C@@H](C)C)N4C(=O)NCCC4
Sinónimos:- A 157378.0
- 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, (αS)-
- 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, (αS)-
- (αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
- 1(2H)-Pyrimidineacetamide, N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, [1S-[1R*(R*),3R*,4R*]]-
- ABT 378
- ABT-378
- UNII-2494G1JF75
- Kaletra
- (S)-N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
- (1S-(1R*(R*),3R*,4R*))-N-(4-(((2,6-Dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
- Ver más sinónimos
Ordenar por
Lopinavir for system suitability CRS
CAS:Lopinavir for system suitability CRSFórmula:C37H48N4O5Peso molecular:628.8008Lopinavir for peak identification CRS
CAS:Lopinavir for peak identification CRSFórmula:C37H48N4O5Peso molecular:628.8008Lopinavir
CAS:Anti-viral; HIV protease inhibitorFórmula:C37H48N4O5Pureza:Min. 97.5 Area-%Forma y color:White Off-White PowderPeso molecular:628.8 g/mol(αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
CAS:Fórmula:C37H48N4O5Pureza:%Forma y color:SolidPeso molecular:628.8008Lopinavir
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFórmula:C37H48N4O5Forma y color:White Off-White PowderPeso molecular:628.36247Lopinavir
CAS:Fórmula:C37H48N4O5Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:628.81Lopinavir EP Impurity H
CAS:Fórmula:C29H32N2O4Forma y color:White To Off-White SolidPeso molecular:472.58N5-Des[(2,6-dimethylphenoxy)acetyl] N5-Formal Lopinavir
CAS:Producto controladoFórmula:C28H38N4O4Forma y color:NeatPeso molecular:494.63Lopinavir
CAS:Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation.Fórmula:C37H48N4O5Pureza:98% - 99.62%Forma y color:White Crystalline SolidPeso molecular:628.8Lopinavir
CAS:Fórmula:C37H48N4O5Pureza:≥ 98.0% (anhydrous basis)Forma y color:White crystalline powderPeso molecular:628.80Lopinavir, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C37H48N4O5Pureza:98%Forma y color:White to beige, PowderPeso molecular:628.81Lopinavir - Bio-X ™
CAS:Chemically derived from ritonavir, Lopinavir belongs to the amphetamines. Lopinavir is clinically used in the prevention and treatment of HIV infections as it acts as HIV-1 protease inhibitor. In 2020, lopinavir was tested to treat COVID-19 patients and although it led to a higher rate of gastrointestinal side effects, the Lopinavir-treated group had a lower incidence of severe complications. Overall it was deemed not to work as a treatment. Lopinavir is part of our Bio-X™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C37H48N4O5Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:628.8 g/mol
![(αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pen…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003RD4.jpg&w=3840&q=75)
![N5-Des[(2,6-dimethylphenoxy)acetyl] N5-Formal Lopinavir](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FD288205.jpg&w=3840&q=75)
