CAS 193681-12-8: alamifovir
Descripción:
alamifovir, con el número CAS 193681-12-8, es un compuesto antiviral que pertenece a la clase de análogos de nucleósidos. Se investiga principalmente por su posible uso en el tratamiento de infecciones virales, particularmente VIH. La estructura química de alamifovir presenta un esqueleto de nucleósido modificado, que le permite interferir con la replicación viral al inhibir la transcriptasa inversa, una enzima esencial para el ciclo de vida de los retrovirus. alamifovir exhibe características típicas de los análogos de nucleósidos, incluida la capacidad de imitar nucleótidos naturales, incorporándose así al ARN o ADN viral y interrumpiendo el proceso de síntesis. Su perfil farmacológico sugiere una biodisponibilidad favorable y un potencial para la administración oral. La investigación sobre alamifovir se ha centrado en su eficacia, seguridad y patrones de resistencia, así como en su papel en terapias combinadas para mejorar la efectividad antiviral. Al igual que con muchos agentes antivirales, los estudios en curso buscan dilucidar su completo potencial terapéutico y optimizar su uso en entornos clínicos.
Fórmula:C18H18F6N5O4PS
InChI:InChI=1/C18H18F6N5O4PS/c19-17(20,21)8-32-34(30,33-9-18(22,23)24)11-31-7-6-29-10-26-13-14(29)27-16(25)28-15(13)35-12-4-2-1-3-5-12/h1-5,10H,6-9,11H2,(H2,25,27,28)
SMILES:c1ccc(cc1)Sc1c2c([nH]c(=N)n1)n(CCOCP(=O)(OCC(F)(F)F)OCC(F)(F)F)cn2
Sinónimos:- Alamifovir [INN]
- Bis(2,2,2-trifluoroethyl) ((2-(2-amino-6-((4-methoxyphenyl)sulfanyl)-9H-purin-9-yl)ethoxy)methyl)phosphonate
- Ly 582563
- Ly582563
- Mcc 478
- Unii-0N739K2A8A
- Phosphonic acid, ((2-(2-amino-6-((4-methoxyphenyl)thio)-9H-purin-9-yl)ethoxy)methyl)-, bis(2,2,2-trifluoroethyl) ester
- bis(2,2,2-trifluoroethyl) ({2-[2-amino-6-(phenylsulfanyl)-9H-purin-9-yl]ethoxy}methyl)phosphonate
- Alamifovir
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Encontrado 2 productos.
Alamifovir
CAS:Alamifovir is an antiviral agent, which is synthetically derived. The mode of action of Alamifovir involves the inhibition of viral replication within host cells by targeting specific viral enzymes crucial for the replication process. This interference with the viral life cycle diminishes the ability of the virus to propagate and spread within the host organism. Alamifovir is primarily used in the treatment of viral infections, potentially offering therapeutic benefits for diseases caused by DNA viruses. Its effectiveness is contingent upon its ability to selectively target viral components with minimal cytotoxic effects on host cells, ensuring a beneficial therapeutic index. The applications of Alamifovir in antiviral therapy highlight its relevance in the continuous search for effective treatments against viral pathogens that pose significant clinical challenges. Research into Alamifovir's pharmacokinetics, safety profile, and resistance patterns is ongoing, with the aim of optimizing its use in clinical settings and expanding its utility across a broader spectrum of viral infections.Fórmula:C19H20F6N5O5PSPureza:Min. 95%Peso molecular:575.42 g/molAlamifovir
CAS:Alamifovir: HBV-specific antiviral, purine analog prodrug; active against wild-type/lamivudine-resistant HBV; inhibits DNA initiation/packaging.Fórmula:C19H20F6N5O5PSForma y color:SolidPeso molecular:575.42
