CAS 1953-04-4: Hidrobromuro de galantamina
Descripción:
Hidrobromuro de galantamina es un inhibidor reversible de la enzima acetilcolinesterasa, utilizado principalmente en el tratamiento de la enfermedad de Alzheimer leve a moderada y otros trastornos cognitivos. Es un compuesto de amonio cuaternario derivado de la planta de campanilla y exhibe un mecanismo de acción dual al mejorar la función colinérgica y modular los receptores nicotínicos. La sustancia aparece como un polvo cristalino blanco a blanco amarillento, es soluble en agua y tiene una fórmula molecular que refleja su estructura compleja. Hidrobromuro de galantamina se administra típicamente por vía oral y es conocido por su capacidad para mejorar la función cognitiva y la memoria en los pacientes. Su farmacocinética implica procesos de absorción, distribución, metabolismo y excreción que están influenciados por factores como la edad y la función hepática. Los efectos secundarios comunes pueden incluir náuseas, vómitos y diarrea, que generalmente son leves. Al igual que con cualquier medicamento, es esencial usar Hidrobromuro de galantamina bajo supervisión médica para monitorear la eficacia y las posibles reacciones adversas.
Fórmula:C17H21NO3·BrH
InChI:InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1
Clave InChI:InChIKey=QORVDGQLPPAFRS-XPSHAMGMSA-N
SMILES:O(C)C1=C2C=3[C@]4([C@@](O2)(C[C@@H](O)C=C4)[H])CCN(C)CC3C=C1.Br
Sinónimos:- (4aS,6R,8aS)-6-hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-11-ium
- 5A,6,7,8,8A,12B-Hexahydrogalanthamine Hydrobromide (1:1)
- 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1:1), (4aS,6R,8aS)-
- 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide, (4aS,6R,8aS)-
- Galantamine Hbr
- Galantamine Hydrobromide
- Galanthamine HBr
- Galanthamine Hydrobromide (1:1)
- Galanthamine hydrogen bromide
- Jilkon hydrobromide
- Lycoremine hydrobromide
- Ver más sinónimos
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Galantamine hydrobromide CRS
CAS:Galantamine hydrobromide CRSFórmula:C17H22BrNO3Peso molecular:368.2655Galantamine synthetic for system suitability CRS
CAS:Galantamine synthetic for system suitability CRSFórmula:C17H22BrNO3Peso molecular:368.2655Galantamine natural for system suitability CRS
CAS:Galantamine natural for system suitability CRSFórmula:C17H22BrNO3Forma y color:Crystalline Powder. White. Amorphous.Peso molecular:368.2655Galanthamine hydrobromide
CAS:Producto controladoA reversible and competitive inhibitor of acetylcholinesterase (AChE) that is approved for the treatment of Alzheimer’s disease. It is also an allosteric modulator of nicotinic acetylcholine receptors (nAChR). Activation of nAChR along with upregulation of anti-apoptotic protein Bcl-2 prevents apoptosis and therefore provides neuroprotection.Fórmula:C17H21NO3·HBrPureza:Min. 95%Forma y color:PowderPeso molecular:368.27 g/molGalanthamine-O-methyl-d3 Hydrobromide
CAS:Producto controladoFórmula:C17D3H18NO3·HBrForma y color:NeatPeso molecular:371.284Galantamine Hydrobromide extrapure, 98%
CAS:Fórmula:C17H21NO3·HBrPureza:min. 98%Forma y color:White to off - white, Hygroscopic crystalline powderPeso molecular:368.279-Bromo-7-methoxy-1,2,3,4-tetrahydrobenzofuro[4,3-cd]azepine Hydrobromide
CAS:Producto controladoFórmula:C12H12BrNO2·HBrForma y color:NeatPeso molecular:363.05Galantamine hydrobromide
CAS:Producto controladoFórmula:C17H21NO3·BrHForma y color:NeatPeso molecular:368.27(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide
CAS:Fórmula:C17H22BrNO3Pureza:98%Forma y color:SolidPeso molecular:368.2655Galanthamine hydrobromide
CAS:Centrally active and long-acting acetylcholinesterase inhibitor This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C17H21NO3•HBrPeso molecular:368.27Galantamine hydrobromide
CAS:Galantamine hydrobromideFórmula:C17H21NO3Pureza:77.4%Forma y color:WhitePeso molecular:287.15214Galantamine-d3 HBr
CAS:Fórmula:C17H18D3NO3·HBrForma y color:White To Off-White SolidPeso molecular:290.38 80.91Galantamine hydrobromide impurity standard
CAS:Galantamine hydrobromide impurity standardForma y color:White PowderGalanthamine hydrobromide
CAS:Fórmula:C17H21NO3HBrPureza:≥ 98.0%Forma y color:White powderPeso molecular:368.27Galantamine hydrobromide
CAS:Please enquire for more information about Galantamine hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C17H22BrNO3Pureza:Min. 95%Peso molecular:368.3 g/molGalantamine HBr
CAS:Fórmula:C17H21NO3·HBrForma y color:White To Off-White SolidPeso molecular:287.36 80.91Galantamine Hydrobromide
CAS:Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoiFórmula:C17H21NO3·BrHForma y color:White PowderPeso molecular:367.07831Galantamine Hydrobromide
CAS:Fórmula:C17H21NO3·HBrPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:368.27Galanthamine Hydrobromide
CAS:Producto controladoApplications A selective acetylcholinesterase inhibitor. A therapeutic agent for the treatment and prevention of Alzheimer's disease and other diseases resulting from reduced neuronal metabolism. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Friess, S.L., et al.: Toxicol. Appl. Pharmacol., 3, 347 (1961), Bickel, U., et al.: Clin. Pharmacol. Ther., 50, 420 (1991), Harvey, A.L., et al.: Pharmacol. Ther., 68, 113 (1995),Fórmula:C17H21NO3·BrHForma y color:White To Off-WhitePeso molecular:368.27
![9-Bromo-7-methoxy-1,2,3,4-tetrahydrobenzofuro[4,3-cd]azepine Hydrobromide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FB188550.jpg&w=3840&q=75)
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