CAS 20069-09-4: Piperlongumina
Descripción:
Piperlongumina es un alcaloide natural derivado de la planta Piper longum, comúnmente conocida como pimienta larga. Se caracteriza por su estructura química única, que incluye un anillo de piperidina y una larga cadena de carbono. Este compuesto ha llamado la atención por sus posibles propiedades farmacológicas, incluyendo actividades antiinflamatorias, antioxidantes y anticancerígenas. Se ha demostrado que Piperlongumina induce apoptosis en varias líneas celulares cancerosas y puede aumentar la eficacia de ciertos agentes quimioterapéuticos. Se piensa que su mecanismo de acción implica la modulación de diversas vías de señalización, incluidas las relacionadas con el estrés oxidativo y la supervivencia celular. Además, Piperlongumina exhibe baja toxicidad en células normales, lo que lo convierte en un candidato prometedor para una mayor investigación en terapia contra el cáncer. La sustancia se estudia típicamente en el contexto de sus propiedades bioactivas y aplicaciones terapéuticas potenciales, aunque se necesita más investigación clínica para comprender completamente su eficacia y seguridad en humanos. Al igual que con cualquier compuesto bioactivo, el manejo y la dosificación adecuados son esenciales para un uso seguro.
Fórmula:C17H19NO5
InChI:InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6-15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+
Clave InChI:InChIKey=VABYUUZNAVQNPG-BQYQJAHWSA-N
SMILES:O(C)C1=C(OC)C(OC)=CC(/C=C/C(=O)N2C(=O)C=CCC2)=C1
Sinónimos:- 2(1H)-Pyridinone, 5,6-dihydro-1-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)-, (E)-
- 2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-
- 2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-
- 2(1H)-Pyridone, 5,6-dihydro-1-(3,4,5-trimethoxycinnamoyl)-
- 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone
- Piperlongumine
- Piperlonguminine
- Piplartin
- Piplartine
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Encontrado 13 productos.
Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Fórmula:C17H19NO5Pureza:97.03% - 99.89%Forma y color:SolidPeso molecular:317.34Piperlongumine
CAS:Piperlongumine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Fórmula:C17H19NO5Pureza:(HPLC) ≥90%Forma y color:PowderPeso molecular:317.35Piperlongumine
CAS:Piperlongumine is a naturally occurring alkaloid, which is isolated from the fruit of the Piper longum plant. This compound has shown promise due to its selective cytotoxicity toward cancer cells. Its mode of action involves elevating reactive oxygen species (ROS) levels within cells, leading to oxidative stress that preferentially affects cancerous cells, which exhibit higher basal levels of oxidative stress compared to normal cells. The use of Piperlongumine is primarily in the research and investigation of its potential anticancer properties. Studies focus on its selective lethality against a variety of cancer types and the underlying mechanisms contributing to this effect. Researchers are particularly interested in its ability to target and selectively kill malignant cells while sparing healthy ones, offering a possible avenue for therapeutic intervention. Additionally, ongoing research explores enhancements to its efficacy and bioavailability, as well as its combinatorial effects with existing chemotherapeutic agents. Scientists continue to investigate its comprehensive range of bioactivities and establish its place in the context of cancer treatment strategies.Fórmula:C17H19NO5Pureza:Min. 95%Forma y color:PowderPeso molecular:317.34 g/molPiperlongumine
CAS:PiperlongumineFórmula:C17H19NO5Pureza:By hplc: 98.78% (Typical Value in Batch COA)Forma y color: off-white powderPeso molecular:317.34g/molPiperlongumine
CAS:Producto controladoStability Light Sensitive Applications Piperlongumine (PL), a new alkaloid abundantly present in Piper longum fruits strongly inhibited platelet cell aggregation. It may have anti-cancer properties. It selectively targets and kills cancer cells but leaving normal cells unharmed. References Beretz, A., et al.: Planta Med., 57, 68 (1991), Lee, S., et al.: J. Microbiol. Biotechnol., 12, 679 (2002), Lee, K., et al.: Pharmacol. Res., 53, 265 (2006),Fórmula:C17H19NO5Forma y color:NeatPeso molecular:317.34Piperlongumine
CAS:Fórmula:C17H19NO5Pureza:>97.0%(HPLC)Forma y color:White to Orange to Green powder to crystalPeso molecular:317.34Ref: 10-F302580
1gA consultar5gA consultar1mgA consultar5mgA consultar10mgA consultar25mgA consultar100mgA consultar250mgA consultar500mgA consultar2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-
CAS:Fórmula:C17H19NO5Pureza:98%Forma y color:SolidPeso molecular:317.3365Ref: IN-DA002CWY
1g579,00€5gA consultar1mg30,00€5mg57,00€10mg65,00€25mg79,00€100mg116,00€250mg183,00€500mg240,00€Piperlongumine
CAS:Fórmula:C17H19NO5Pureza:≥ 97%Forma y color:White to off-white crystalline powderPeso molecular:317.34Piperlongumine
CAS:LactamsFórmula:C17H19NO5Pureza:≥ 90.0 % (HPLC)Forma y color:PowderPeso molecular:317.34
![2(1H)-Pyridinone, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA002CWY.jpg&w=3840&q=75)
