CAS 202138-50-9: Fumarato de tenofovir disoproxilo
Descripción:
Fumarato de tenofovir disoproxilo (TDF) es un medicamento antirretroviral utilizado principalmente en el tratamiento de infecciones por VIH y hepatitis B crónica. Es un profármaco de tenofovir, lo que significa que se metaboliza en el cuerpo a su forma activa. TDF se caracteriza por su capacidad para inhibir la enzima transcriptasa inversa, evitando así la replicación viral. El compuesto es un polvo cristalino blanco a blanco amarillento, soluble en agua, y tiene una fórmula molecular que refleja su estructura compleja, incluyendo una sal de fumarato. TDF se administra típicamente por vía oral y es conocido por su favorable perfil farmacocinético, permitiendo una dosificación una vez al día. A menudo se utiliza en combinación con otros agentes antirretrovirales para mejorar la eficacia y reducir el riesgo de resistencia. Los efectos secundarios comunes pueden incluir deterioro renal y pérdida de densidad mineral ósea, lo que requiere monitoreo durante el tratamiento. En general, Fumarato de tenofovir disoproxilo desempeña un papel crucial en la terapia moderna del VIH y es un componente clave de muchos regímenes de tratamiento.
Fórmula:C19H30N5O10P·C4H4O4
InChI:InChI=1/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/t14-;/m1./s1
SMILES:C([C@H](OCP(OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)C)N1C=2C(N=C1)=C(N)N=CN2.C(=C/C(O)=O)\C(O)=O
Sinónimos:- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
- 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide, (R)-, (E)-2-butenedioate (1:1)
- 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine fumarate
- Gs 4331-05
- PMPA Prodrug
- Tenofovir DF
- Tenofovir Dipivoxil Fumarate
- Tenofovir Disproxil Fumarate
- Virea
- Viread
- Ver más sinónimos
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Encontrado 18 productos.
TENOFOVIR DISOPROXIL FUMARATE RS
CAS:TENOFOVIR DISOPROXIL FUMARATE RSFórmula:C23H34N5O14PPeso molecular:635.5149Tenofovir disoproxil fumarate
CAS:Fórmula:C23H34N5O14PPureza:≥ 98.0%Forma y color:White to off-white crystalline powderPeso molecular:635.52Tenofovir disoproxil fumarate - Bio-X ™
CAS:Tenofovir disoproxil is a nucleotide analog reverse transcriptase inhibitor that is used to treat infections such as Hepatitis-B and HIV. This drug is an antiretroviral agent that blocks reverse transcriptase, blocking viral replication. Tenofovir disoproxil fumarate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C23H34N5O14PPureza:Min. 95%Forma y color:PowderPeso molecular:635.52 g/molTenofovir disoproxil fumarate
CAS:Anti-viral; reverse transcriptase inhibitorFórmula:C23H34N5O14PPureza:Min. 97.5 Area-%Forma y color:White Off-White PowderPeso molecular:635.52 g/mol2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
CAS:Fórmula:C23H34N5O14PPureza:99%Forma y color:SolidPeso molecular:635.5149Tenofovir Disoproxil Fumarate
CAS:Applications Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),Fórmula:C19H30N5O10P·C4H4O4Forma y color:White To Off-WhitePeso molecular:635.51Tenofovir Disoproxil Fumarate
CAS:Fórmula:C19H30N5O10P·C4H4O4Forma y color:White To Off-White SolidPeso molecular:519.45 116.07Tenofovir Disoproxil Fumarate
CAS:Producto controladoFórmula:C19H30N5O10P·C4H4O4Forma y color:NeatPeso molecular:635.51Tenofovir Disoproxil Fumarate
CAS:Fórmula:C19H30N5O10P·C4H4O4Pureza:>95.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:635.51Tenofovir Disoproxil Fumarate
CAS:Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, a nucleoside reverse transcriptase inhibitor analog of adenosine.Fórmula:C19H30N5O10P·C4H4O4Pureza:98.60% - 99.02%Forma y color:White To Pink CrystallinePeso molecular:635.51Ref: TM-T2409L
10mg50,00€25mg74,00€50mg90,00€100mg124,00€200mg168,00€500mg240,00€1mL*10mM (DMSO)55,00€Tenofovir disoproxil fumarate, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C23H34N5O14PPureza:98%Forma y color:White to off-white, PowderPeso molecular:635.52Tenofovir Disoproxil-d6 Fumarate
CAS:Producto controladoStability Hygroscopic Applications Isotope labelled Tenofovir Disoproxil Fumarate, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),Fórmula:C19H24D6N5O10P•C4H4O4Forma y color:White To Off-WhitePeso molecular:525.4811607Tenofovir Disoproxil Fumarate
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFórmula:C19H30N5O10P·C4H4O4Forma y color:White Off-White PowderPeso molecular:635.51
![2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]meth…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA002836.jpg&w=3840&q=75)
