CAS 2058-46-0: Clorhidrato de oxitetraciclina
Descripción:
Clorhidrato de oxitetraciclina es un antibiótico de amplio espectro que pertenece a la clase de las tetraciclinas, utilizado principalmente en el tratamiento de diversas infecciones bacterianas. Se caracteriza por su capacidad para inhibir la síntesis de proteínas en las bacterias al unirse a la subunidad ribosomal 30S, evitando así el crecimiento y la reproducción de microorganismos susceptibles. Este compuesto se presenta típicamente como un polvo cristalino de color amarillo a marrón amarillento, que es soluble en agua y ligeramente soluble en alcohol. Su fórmula molecular es C22H24N2O9·HCl, y tiene un peso molecular que refleja su estructura compleja, que incluye múltiples grupos funcionales hidroxilo y cetona. Clorhidrato de oxitetraciclina es efectivo contra una amplia gama de bacterias grampositivas y gramnegativas, así como algunos protozoos. Se utiliza comúnmente en medicina humana y veterinaria, y su uso está asociado con efectos secundarios potenciales, incluidos trastornos gastrointestinales y fotosensibilidad. Debido al riesgo de resistencia a los antibióticos, su uso debe ser cuidadosamente monitoreado y guiado por pruebas de susceptibilidad.
Fórmula:C22H24N2O9·ClH
InChI:InChI=1S/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H/t12-,13-,14+,17+,21-,22+;/m1./s1
Clave InChI:InChIKey=UBDNTYUBJLXUNN-IFLJXUKPSA-N
SMILES:O[C@@]12[C@@]([C@@H](O)[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl
Sinónimos:- (2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
- (3E,11S)-3-[amino(hydroxy)methylidene]-4a,6,7,11,12-pentahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride
- (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
- (4S-(4Alpha,4Aalpha,5Alpha,5Aalpha,6Beta,12Aalpha))-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,6,10,12,12A-Hexahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide Monohydrochloride
- 1-Dimethylamino-1,4,6,11,12,13,14,18-octahydro-2,5,7,11,12,14-hexahydroxy-4,6-dioxo-11-methylnaphthacene-3-carbonamide hydrochloride
- 10,12,12A-Hexahydroxy-6-Methyl-1,11-Dioxo-Monohydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aR,5S,5aR,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5α,5aα,6β,12aα)]-
- 5-Hydroxytetracycline Hydrochloride
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OXYTETRACYCLINE HYDROCHLORIDE CRS
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CAS:Fórmula:C22H24N2O9·ClHForma y color:Single SolutionPeso molecular:496.89Oxytetracycline Hydrochloride
CAS:Stability Hygroscopic Applications Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial. References Finlay, et al.: Science, 111, 85 (1950), Weiss, et al.: Antibiot. Chemother., 7, 374 (1957), Kruse, H., et al.: Microb. Drug. Resist., 5, 135, (1999), van den Bogaard, A., et al.: J. Antimicrob. Chemother., 45, 663 (2000), Nwosu, V., et al.: Res. Microbiol., 152, 421 (2001),Fórmula:C22H24N2O9·ClHForma y color:YellowPeso molecular:496.89Oxytetracycline hydrochloride
CAS:A broad-spectrum antibiotic of tetracycline class which inhibits protein synthesis by targeting the 30S ribosome subunit. It has been used in human medicine as well as in veterinary medicine and agriculture.Fórmula:C22H24N2O9•HClPureza:Min. 95%Forma y color:Yellow PowderPeso molecular:496.89 g/molOxytetracycline-¹³CD₃ Hydrochloride (>85%)
CAS:Producto controladoFórmula:CC21D3H21N2O9·HClPureza:>85%Forma y color:NeatPeso molecular:500.906Oxytetracycline Hydrochloride
CAS:Producto controladoFórmula:C22H24N2O9·ClHForma y color:NeatPeso molecular:496.89Oxytetracycline Hydrochloride
CAS:Lactams, nesoiFórmula:C22H24N2O9·HClForma y color:Yellow PowderPeso molecular:460.14818Oxytetracycline hydrochloride
CAS:Producto controladoFórmula:C22H24N2O9·ClHForma y color:NeatPeso molecular:496.89Oxytetracycline HCl
CAS:Fórmula:C22H24N2O9·HClForma y color:White To Off-White SolidPeso molecular:460.44 36.46Oxytetracycline hydrochloride
CAS:Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C22H25ClN2O9Forma y color:Yellow, Powder or crystals or crystalline powderPeso molecular:496.90Oxytetracycline Hydrochloride (OTC), 95%
CAS:Fórmula:C22H24N2O9·HClPureza:min. 95%Forma y color:Yellow, Crystalline powderPeso molecular:496.90PharmaVetResiMix 5 Tetracyclines-v10 10 µg/mL in Methanol
CAS:Producto controladoForma y color:MixtureOxytetracycline hydrochloride
CAS:Fórmula:C22H25ClN2O9Pureza:97%Forma y color:SolidPeso molecular:496.8949
