CAS 208538-73-2: Sodio de Micafungina
Descripción:
Sodio de Micafungina es un agente antifúngico que pertenece a la clase de las equinocandinas, utilizado principalmente en el tratamiento de infecciones fúngicas invasivas, particularmente aquellas causadas por especies de Candida y Aspergillus. Funciona inhibiendo la síntesis de β-(1,3)-D-glucano, un componente esencial de la pared celular fúngica, comprometiendo así la integridad estructural del hongo y llevando a la lisis celular. La micafungina se administra típicamente por vía intravenosa y se caracteriza por su actividad de amplio espectro contra varios patógenos fúngicos, lo que la convierte en una opción valiosa en entornos clínicos, especialmente para pacientes inmunocomprometidos. La sustancia es soluble en agua y exhibe estabilidad bajo condiciones fisiológicas. Su farmacocinética implica una vida media relativamente larga, lo que permite una dosificación una vez al día. Los efectos secundarios comunes pueden incluir reacciones relacionadas con la infusión, elevaciones de enzimas hepáticas y trastornos gastrointestinales. Debido a su mecanismo de acción y perfil de seguridad, la micafungina a menudo se prefiere en casos donde otras terapias antifúngicas pueden ser menos efectivas o contraindicadas.
InChI:InChI=1/C56H71N9O23S.Na/c1-4-5-6-17-86-32-14-11-28(12-15-32)39-21-33(63-87-39)27-7-9-29(10-8-27)49(75)58-34-20-38(70)52(78)62-54(80)45-46(72)25(2)23-65(45)56(82)43(37(69)22-41(57)71)60-53(79)44(48(74)47(73)30-13-16-36(68)40(18-30)88-89(83,84)85)61-51(77)35-19-31(67)24-64(35)55(81)42(26(3)66)59-50(34)76;/h7-16,18,21,25-26,31,34-35,37-38,42-48,52,66-70,72-74,78H,4-6,17,19-20,22-24H2,1-3H3,(H2,57,71)(H,58,75)(H,59,76)(H,60,79)(H,61,77)(H,62,80)(H,83,84,85);/q;+1/p-1/t25-,26-,31+,34?,35-,37+,38+,42-,43-,44-,45-,46-,47+,48?,52-;/m1./s1
SMILES:CCCCCOc1ccc(cc1)c1cc(c2ccc(cc2)C(=O)NC2CC(C(N=C(C3C(C(C)CN3C(=O)C(C(CC(=N)O)O)N=C(C(C(C(c3ccc(c(c3)OS(=O)(=O)O)O)O)O)N=C(C3CC(CN3C(=O)C(C(C)O)N=C2O)O)O)O)O)O)O)O)no1.[Na]
Sinónimos:- Fk 463
- 5-((1S,2S)-2-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-20-((1R)-3-Amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((1R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxo-9-((4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzoyl)amino)tetracosahydro-1H-dipyrrolo(2,1-c:2',1'-l)(1,4,7,10,13,16)hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl sodium sulfate
- Fk463
- Unii-Is1Up79R56
- Pneumocandin A0, 1-((4R,5R)-4,5-dihydroxy-N2-(4-(5-(5-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxy-3-(sulfooxy)phenyl)-L-threonine)-, monosodium salt
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Encontrado 11 productos.
Micafungin-¹³C₆ Sodium
CAS:Producto controladoFórmula:C50C6H70N9NaO23SForma y color:NeatPeso molecular:1298.22Micafungin Sodium
CAS:Fórmula:C56H70N9O23SNaPureza:≥97% (HPLC)Forma y color:white to beige powderPeso molecular:1292.26Pneumocandin A0, 1-[(4R,5R)-4,5-dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-, sodium salt (1:1)
CAS:Fórmula:C53H67N8O20SPureza:98%Forma y color:SolidPeso molecular:1168.2057Micafungin sodium - Bio-X ™
CAS:Micafungin, as one of three echinocandina, has been proven to be a successful antifungal therapeutic in treating general Candida fungus infections. The treatment of immunocompromised patients is particularly important as Candida infections cause high mortality rates in patients in intensive care units, receiving chemotherapy, or stem cell transplants. This product acts as an anti-fungal by inhibiting the 1,3-beta-D-glucan synthase enzyme. As a result the production of 1,3-beta-D-glucan, which is crucial to the fungal cell wall, is hindered. Thus, the fungal cell wall loses integrity allowing for osmotic instability and cell lysis to occur. Micafungin sodium is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C56H71N9O23S•NaPureza:Min. 95%Forma y color:PowderPeso molecular:1,293.27 g/molMicafungin Sodium (INTERNATIONAL COLD SHIPMENT REQUIRED)
CAS:Antibiotics nesoiFórmula:C56H70N9NaO23SForma y color:White PowderPeso molecular:1291.4203Micafungin sodium
CAS:Micafungin sodium (FK 463) is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetriFórmula:C56H70N9NaO23SPureza:98% - 99.6%Forma y color:SolidPeso molecular:1292.26Ref: TM-T1794
2mg47,00€5mg69,00€10mg105,00€25mg205,00€50mg329,00€100mg525,00€500mg1.159,00€1mL*10mM (DMSO)150,00€Micafungin sodium
CAS:Fórmula:C56H71N9O23S·NaPureza:≥ 98.0% (anhydrous)Forma y color:White to off-white or beige powderPeso molecular:1292.28Micafungin Sodium Salt
CAS:Fórmula:C56H70N9O23S·NaForma y color:White To Off-White Solid SolidPeso molecular:1269.29 22.99Micafungin-d11 Sodium
CAS:Producto controladoApplications Micafungin-d11 Sodium is the isotope labelled analog of Micafungin Sodium (M342350); an echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall. Micafungin Sodium also represents a valuable treatment option for fungal infections. References Chen, S.C. et al.: Drugs, 71, 11 (2011); Groll, A.H. et al.: Opin. Anti-Infect. Invest. Drugs, 2, 405 (2000); Tomishima, M. et al.: J. Antibiot., 52, 674 (1999)Fórmula:C56H59D11N9NaO23SForma y color:NeatPeso molecular:1303.33Micafungin Sodium
CAS:Stability Hygroscopic Applications An echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. References Chen, S.C. et al.: Drugs, 71, 11 (2011); Groll, A.H. et al.: Opin. Anti-Infect. Invest. Drugs, 2, 405 (2000); Tomishima, M. et al.: J. Antibiot., 52, 674 (1999);Fórmula:C56H70N9O23S·NaForma y color:Off WhitePeso molecular:1292.26Micafungin sodium
CAS:Anti-fungal; glucan synthase inhibitorFórmula:C56H70N9NaO23SPureza:Min. 97 Area-%Forma y color:White PowderPeso molecular:1,292.26 g/mol
![Pneumocandin A0, 1-[(4R,5R)-4,5-dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-o…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA002JQV.jpg&w=3840&q=75)
