CAS 23313-80-6: Clorhidrato de epitetraciclina
Descripción:
Clorhidrato de epitetraciclina es un derivado semisintético de la tetraciclina, clasificado como un antibiótico. Exhibe una actividad antibacteriana de amplio espectro, dirigiéndose principalmente a bacterias Gram-positivas y Gram-negativas al inhibir la síntesis de proteínas mediante la unión a la subunidad ribosomal 30S. Este compuesto se caracteriza por su estabilidad en condiciones ácidas, lo que mejora su biodisponibilidad. Clorhidrato de epitetraciclina se administra típicamente por vía oral y es conocido por sus aplicaciones terapéuticas en el tratamiento de diversas infecciones, incluidas las infecciones respiratorias y del tracto urinario. La forma de clorhidrato mejora la solubilidad en agua, facilitando su uso en formulaciones farmacéuticas. Además, posee propiedades antiinflamatorias, lo que lo hace útil en el tratamiento de condiciones como el acné. Sin embargo, al igual que otros tetraciclinas, puede causar efectos secundarios como trastornos gastrointestinales y fotosensibilidad. Es importante señalar que el uso de Clorhidrato de epitetraciclina debe ser guiado por pruebas de susceptibilidad para evitar el desarrollo de resistencia. En general, este compuesto desempeña un papel significativo en la medicina moderna, particularmente en el tratamiento de infecciones bacterianas.
Fórmula:C22H24N2O8·ClH
InChI:InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15+,21+,22-;/m0./s1
Clave InChI:InChIKey=XMEVHPAGJVLHIG-DXDJYCPMSA-N
SMILES:O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl
Sinónimos:- Epitetracycline hydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4R,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4R,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4R-(4α,4aβ,5aβ,6α,12aβ)]-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, 4-epimer
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Encontrado 14 productos.
4-Epitetracycline hydrochloride RS
CAS:4-Epitetracycline hydrochloride RSFórmula:C22H24N2O8Peso molecular:444.4346PharmaVetResiMix 5 Tetracyclines-v10 10 µg/mL in Methanol
CAS:Producto controladoForma y color:Mixture4-Epitetracycline hydrochloride
CAS:Producto controladoFórmula:C22H24N2O8·ClHForma y color:NeatPeso molecular:480.904-epi-Tetracycline Hydrochloride
CAS:Producto controladoApplications Metabolite of Tetracycline (T291400). This compound is a contaminant of emerging concern (CECs). References Diana, J., et al.: J. Pharm. Biomed. Anal., 39, 523 (2005), Fritz, J., et al.: Food Chem., 105, 1297 (2007), Gratacos-Cubarsi, M., et al.: J. Agric. Food Chem., 55, 4610 (2007),Fórmula:C22H24N2O8·ClHForma y color:YellowPeso molecular:480.904-Epitetracycline hydrochloride
CAS:Epitetracycline is an epimer of the antibiotic tetracycline . Epimers of tetracycline form without catalysis and are considered degradation products. Epitetracycline has decreased activity as an antibiotic or a Tet repressor effector but may have stronger toxic effects in animals.Fórmula:C22H25ClN2O8Forma y color:SolidPeso molecular:480.9Epitetracycline Hydrochloride
CAS:Tetracyclines and their derivatives; salts thereofFórmula:C22H24N2O8·HClForma y color:Yellow PowderPeso molecular:444.153274-Epitetracycline hydrochloride
CAS:4-Epitetracycline hydrochloride is a tetracycline antibiotic derivative, which is a secondary metabolite derived from bacterial sources, particularly Streptomyces species. It functions primarily by inhibiting protein synthesis in bacteria through binding to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA to the RNA-ribosome complex. This action hinders bacterial growth by interfering with vital processes necessary for bacterial survival and replication. The uses and applications of 4-Epitetracycline hydrochloride are predominantly within research settings to study its pharmacokinetics, pharmacodynamics, and potential therapeutic effects compared to other tetracyclines. It is of particular interest for understanding antibiotic resistance mechanisms and assessing effectiveness against both gram-positive and gram-negative bacteria. Researchers may also explore the conditions that alter its activity, stability, and bioavailability. Despite its structural similarity to tetracycline, its altered chemical structure can contribute to differing biological activity, offering insight into the development of new antibiotic compounds with improved efficacy and reduced side effects. The derivative form allows scientists to investigate alternative pathways and effects that are unique from its parent compound.Fórmula:C22H25ClN2O8Pureza:Min. 95%Forma y color:PowderPeso molecular:480.9 g/mol4-Epitetracycline hydrochloride, can be used as a secondary standard
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C22H25ClN2O8Forma y color:Yellow, Crystalline powderPeso molecular:480.904-Epitetracycline Hydrochloride
CAS:Producto controladoFórmula:C22H24N2O8·ClHForma y color:NeatPeso molecular:480.90
