CAS 29611-03-8: (1S,6aR,9aS)-2,3,6a,9a-Tetrahidro-1-hidroxi-4-metoxiciclopenta[c]furo[3′,2′:4,5]furo[2,3-h][1]benzopirano-11(1H)-ona

Aflatoxicol

Aflatoxin (Aflatoxin R0) is a mutagenic and carcinogenic mycotoxin derived from aflatoxin B1 through metabolic processes facilitated by Rhizopus spp.

Stability Hygroscopic Applications Aflatoxicol is a reduction metabolite of Aflatoxin B1 (A357460), which is a potent environmental mutagen and carcinogen. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Cifford, R., et al.: Nature, 209, 312 (1966); Wogan, et al.: Food Cosmet. Toxicol., 12, 681 (1974); Sinz, M.W., et al.: J. Toxicol. Toxin Rev., 10, 87 (1991); Breinholt, V., et al.: Chem. Res. Toxicol., 8, 506 (1995); Lee, S., et al.: J. Agric. Food Chem., 49, 5171 (2001);

Aflatoxicol is a derivative of aflatoxin, which is a type of mycotoxin. It is derived from the biochemical transformation of aflatoxins, predominantly by metabolic reduction, often sourced from specific fungi such as *Aspergillus flavus* and *Aspergillus parasiticus*. The mode of action of aflatoxicol involves its interaction with cellular macromolecules, causing disruption and potentially leading to toxic effects, similar to its parent compound. It is known to cause DNA adduct formation, ultimately interfering with genetic integrity. The uses and applications of aflatoxicol are primarily found in scientific research settings, particularly in toxicology and biochemistry. It serves as a critical compound in the study of carcinogenic processes and the biotransformation pathways of aflatoxins. By investigating aflatoxicol, scientists gain insights into the mechanisms of aflatoxin toxicity and its biological consequences in living organisms. This research can be pivotal in understanding human health risks and in developing strategies to mitigate exposure in agricultural and food safety contexts.