CAS 306296-47-9: Vicriviroc
Descripción:
Vicriviroc es una pequeña molécula que funciona como un antagonista de CCR5, desarrollado principalmente para el tratamiento de la infección por VIH. Se une selectivamente al co-receptor CCR5 en la superficie de las células inmunitarias, inhibiendo la entrada del VIH en estas células y, por lo tanto, previniendo la replicación viral. El compuesto se caracteriza por su capacidad para bloquear la interacción entre el VIH y el receptor CCR5, que es crucial para la capacidad del virus de infectar las células huésped. Vicriviroc ha sido estudiado en ensayos clínicos por su eficacia y perfil de seguridad, demostrando beneficios potenciales en pacientes con cepas de VIH tropicas de CCR5. Su estructura química incluye una disposición compleja de átomos de carbono, hidrógeno, nitrógeno y oxígeno, que contribuyen a sus propiedades farmacológicas. Al igual que con muchos agentes antirretrovirales, es esencial monitorear los posibles efectos secundarios y el desarrollo de resistencia durante el tratamiento. En general, Vicriviroc representa un avance significativo en las opciones terapéuticas disponibles para el manejo de la infección por VIH, particularmente en casos donde las terapias tradicionales pueden no ser efectivas.
Fórmula:C28H38F3N5O2
InChI:InChI=1S/C28H38F3N5O2/c1-19-16-35(14-15-36(19)24(17-38-5)22-6-8-23(9-7-22)28(29,30)31)27(4)10-12-34(13-11-27)26(37)25-20(2)32-18-33-21(25)3/h6-9,18-19,24H,10-17H2,1-5H3/t19-,24-/m0/s1
Clave InChI:InChIKey=CNPVJJQCETWNEU-CYFREDJKSA-N
SMILES:[C@@H](COC)(N1[C@@H](C)CN(CC1)C2(C)CCN(C(=O)C=3C(C)=NC=NC3C)CC2)C4=CC=C(C(F)(F)F)C=C4
Sinónimos:- (4,6-Dimethyl-5-pyrimidinyl)[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-1-piperidinyl]methanone
- 5-({4-[(3S)-4-{(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl}-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl}carbonyl)-4,6-dimethylpyrimidine
- 5-[4-[4-[2-methoxy-1(R)-[4-(trifluoromethyl)phenyl]ethyl]-3(S)-methylpiperazin-1-yl]-4-methylpiperidin-1-ylcarbonyl]-4,6-dimethylpyrimidine
- Methanone, (4,6-dimethyl-5-pyrimidinyl)[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-1-piperidinyl]-
- Mk 7690
- Piperidine, 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-
- Sch-417690
- Sch-D
- Vicriviroc
- Vicroviroc
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Encontrado 4 productos.
Vicriviroc
CAS:Vicriviroc is an investigational pharmaceutical compound, specifically classified as an HIV entry inhibitor. It originates from a synthetic source, designed to target the CCR5 co-receptor on human immune cells. The mode of action involves blocking this co-receptor, thereby preventing the HIV virus from binding and fusing with the host cell membrane. This inhibition effectively obstructs the virus's ability to enter and infect the host cells, particularly those within the chemokine receptor family. Vicriviroc's primary use is as a potential antiretroviral agent in the treatment of HIV-1 infection. Its application focuses on patients whose strains of HIV predominantly use the CCR5 receptor for cellular entry. By interfering with the virus's entry mechanism, Vicriviroc aims to reduce viral load and impede disease progression. Although it has shown promise in clinical trials, ongoing research and development continue to evaluate its efficacy and safety in comparison to existing therapeutic options.Fórmula:C28H38F3N5O2Pureza:Min. 95%Peso molecular:533.63 g/molMethanone, (4,6-dimethyl-5-pyrimidinyl)[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-1-piperidinyl]-
CAS:Fórmula:C28H38F3N5O2Peso molecular:533.6288Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Fórmula:C28H38F3N5O2Forma y color:SolidPeso molecular:533.63
![Methanone, (4,6-dimethyl-5-pyrimidinyl)[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]eth…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0030PD.jpg&w=3840&q=75)
