CAS 312-84-5: D-Serina
Descripción:
D-Serina es un aminoácido que actúa como co-agonista en el receptor N-metil-D-aspartato (NMDA), desempeñando un papel crucial en la neurotransmisión y la plasticidad sináptica en el sistema nervioso central. Es una molécula quiral, existiendo como el enantiómero D de la serina, y se clasifica como un aminoácido no proteico. D-Serina es soluble en agua y presenta un pH neutro en solución. Su estructura presenta un grupo hidroximetilo, que contribuye a su actividad biológica. D-Serina está involucrado en varios procesos fisiológicos, incluyendo funciones cognitivas y neurodesarrollo, y se ha estudiado por sus posibles efectos terapéuticos en condiciones como la esquizofrenia y enfermedades neurodegenerativas. Además, se sintetiza en el cuerpo a partir de L-serina a través de la acción de la enzima serina racemasa. Debido a su papel en el sistema nervioso, D-Serina es de gran interés en la investigación en neurociencia, particularmente en la comprensión de los mecanismos sinápticos y la modulación de la señalización glutamatérgica.
Fórmula:C3H7NO3
InChI:InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
Clave InChI:InChIKey=MTCFGRXMJLQNBG-UWTATZPHSA-N
SMILES:[C@H](C(O)=O)(CO)N
Sinónimos:- (2R)-2-Amino-3-hydroxypropanoic acid
- (R)-2-Amino-3-hydroxypropanoic acid
- (R)-Serine
- <span class="text-smallcaps">D</span>-Serine
- D-2-Amino-3-hydroxypropanoic acid
- D-Ser
- D-Ser-OH
- D-Serin
- D-serina
- H-D-Ser-OH
- Nsc 77689
- Ver más sinónimos
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Encontrado 14 productos.
D-Serine extrapure, 99%
CAS:Fórmula:C3H7NO3Pureza:min. 99%Forma y color:White to off-white, Crystalline compound, Clear, ColourlessPeso molecular:105.1D-Serine, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C3H7NO3Pureza:98%Forma y color:Powder or crystals, White to off-whitePeso molecular:105.09D-Serine
CAS:Fórmula:C3H7NO3Pureza:>98.5%(T)Forma y color:White to Almost white powder to crystalPeso molecular:105.09D-Serine
CAS:D-Serine ((R)-Serine) is an endogenous amino acid,is a potent co-agonist at the NMDA glutamate receptor.Fórmula:C3H7NO3Pureza:99.57%Forma y color:SolidPeso molecular:105.09D-Serine
CAS:D-SerineFórmula:C3H7NO3Pureza:98.5%Forma y color: white crystalline solidPeso molecular:105.09g/molD-Serine
CAS:D-Serine is an amino acid that has been shown to have a physiological function in the brain. It is an endogenous coagonist at the glycine site on the N-methyl-D-aspartate (NMDA) receptor. D-Serine has been shown to be neuroprotective and reduce neuronal death in experimental models of Parkinson's disease, Alzheimer's disease, and stroke. D-Serine also has a role in energy metabolism, as it can be converted to serine by racemase. This conversion is critical for neuronal survival during periods of prolonged fasting or low glucose levels. The production of d-serine from l-serine via racemase may serve as a potential biomarker for certain diseases such as Parkinson's disease and Alzheimer's disease.Fórmula:C3H7NO3Forma y color:White PowderPeso molecular:105.09 g/molD-Serine
CAS:Fórmula:C3H7NO3Pureza:98.5 - 101.5 % (dried basis)Forma y color:White to off-white powderPeso molecular:105.09D-Serine
CAS:Producto controladoApplications A proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. Inhibitor of serine palmitoyltransferase. A neuromodulator. References Junjaud, G. et al.: J. Neurochem., 98, 1159 (2006); Hanada, K. et al.: FEBS Lett., 474, 63 (2000); Pollegionni, L. et al.: Cell. Mol. Life Sci., 67, 2387 (2010);Fórmula:C3H7NO3Forma y color:NeatPeso molecular:105.09D-Serine, 99%
CAS:D-Serine is involved in the biosynthesis of purines, pyrimidines, and other amino acids. D-Serine also is an agonist of glycine site of the NMDA-type glutamate receptor. It also acts as Lacosamide intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C3H7NO3Pureza:99%Forma y color:Crystals or powder or crystalline powder, White to pale creamPeso molecular:105.09
