CAS 3237-50-1: 5,5-Dihidroxi-2,4,6(1H,3H,5H)-pirimidinatriona
Descripción:
5,5-Dihidroxi-2,4,6(1H,3H,5H)-pirimidinatriona, también conocido como uracilo-5,5-diol, es un derivado de pirimidina caracterizado por la presencia de dos grupos hidroxilo en la posición 5 y una estructura de triona. Este compuesto presenta un anillo aromático de seis miembros que contiene átomos de nitrógeno, lo que contribuye a su estabilidad y reactividad. Típicamente es un sólido cristalino blanco a blanco sucio, soluble en agua debido a la presencia de grupos hidroxilo que pueden formar enlaces de hidrógeno. El compuesto exhibe propiedades típicas de las pirimidinas, incluida la posible actividad biológica, ya que puede interactuar con ácidos nucleicos y enzimas. Su estructura permite formas tautoméricas, que pueden influir en su reactividad e interacciones en vías bioquímicas. 5,5-Dihidroxi-2,4,6(1H,3H,5H)-pirimidinatriona es de interés en varios campos, incluida la química medicinal y la bioquímica, debido a sus posibles aplicaciones en el desarrollo de fármacos y como sonda bioquímica.
Fórmula:C4H4N2O5
InChI:InChI=1S/C4H4N2O5/c7-1-4(10,11)2(8)6-3(9)5-1/h10-11H,(H2,5,6,7,8,9)
Clave InChI:InChIKey=ZIIHZVKHFWOENY-UHFFFAOYSA-N
SMILES:OC1(O)C(=O)NC(=O)NC1=O
Sinónimos:- 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-dihydroxy-
- 5-24-09-00382 (Beilstein Handbook Reference)
- 5,5-Dihydroxy-2,4,6(1H,3H,5H)-pyrimidinetrione
- 2,4,5,6(1H,3H)-Pyrimidinetetrone, monohydrate
- NSC 221304
- 2,4,5,6(1H,3H)-Pyrimidinetetrone hydrate
- Alloxan hydrate
- 5,5-Dihydroxybarbituric acid
- 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-dihydroxy-
- 5,5-dihydroxypyrimidine-2,4,6(1H,3H,5H)-trione
- BRN 0155548
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Encontrado 5 productos.
5,5-Dihydroxypyrimidine-2,4,6(1H,3H,5H)-trione
CAS:Producto controlado5,5-Dihydroxypyrimidine-2,4,6(1H,3H,5H)-trione is a chemical compound that is found in animals. It is an intermediate in the biosynthesis of pyrimidines. This molecule has been shown to have hypoglycemic effects when administered orally to diabetic patients. 5,5-Dihydroxypyrimidine-2,4,6(1H,3H,5H)-trione can be metabolized by nitro and alkoxy radicals to form reactive oxygen species that are cytotoxic. This chemical also has insulin-like growth factor activity and can stimulate the production of density lipoprotein (LDL).Fórmula:C4H4N2O5Pureza:Min. 95%Peso molecular:160.09 g/molAlloxan monohydrate, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Pureza:98%Forma y color:Crystalline powder, Off-white to yellow to light beigeAlloxan monohydrate, 98%
CAS:Cytotoxic compound that causes oxidative base damage to nuclear DNAAlloxan monohydrate is used as a precursor to prepare purple dye murexide. It is also used in research models to induce diabetes and destroy beta cells. Further, it is a strong oxidizing agent and it forms a hemiacetal with its reduced reaction product dialuric acid. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C4H2N2O4•H2OPureza:98%Forma y color:White to cream to yellow to brown to black, Crystals or powder or crystalline powderPeso molecular:160.09 (142.07anhy)Alloxan hydrate
CAS:A pyrimidine derivative, widely used for the induction of diabetes in experimental animals. It preferentially accumulates in pancreatic β cells in Langerhans islets via glucose transporter GLUT2. In the presence of intracellular thiols such as glutathione, it gets involved in a cyclic redox reaction with its reduction product, dialuric acid. This triggers the production of toxic levels of reactive oxygen species (ROS) and directs the cells in necrosis. Alloxan also inhibits glucokinase, which regulates glucose-induced insulin secretion.Fórmula:C4H2N2O4•xH2OPureza:Min. 95%Peso molecular:142.07 g/mol
