CAS 33570-04-6: Bilobalida
Descripción:
Bilobalida es un compuesto sesquiterpeno de origen natural que se encuentra principalmente en las hojas del árbol Ginkgo biloba. Se reconoce por sus potenciales propiedades neuroprotectoras y a menudo se estudia por sus efectos en la función cognitiva y la mejora de la memoria. Bilobalida se caracteriza por su estructura química única, que incluye un marco bicíclico, lo que contribuye a su actividad biológica. Se sabe que el compuesto exhibe propiedades antioxidantes, ayudando a mitigar el estrés oxidativo en los tejidos neuronales. Además, se ha investigado el papel de Bilobalida en la modulación de los sistemas de neurotransmisores, particularmente en relación con las vías de serotonina y dopamina. Su perfil farmacológico sugiere aplicaciones terapéuticas potenciales en condiciones como la enfermedad de Alzheimer y otros trastornos neurodegenerativos. Sin embargo, aunque Bilobalida muestra promesas, se necesita más investigación para comprender completamente sus mecanismos de acción y eficacia en entornos clínicos. Como compuesto, generalmente se considera seguro, pero al igual que cualquier sustancia, debe usarse con precaución y bajo la guía adecuada, especialmente en forma de suplemento.
Fórmula:C15H18O8
InChI:InChI=1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13-,14+,15+/m0/s1
Clave InChI:InChIKey=MOLPUWBMSBJXER-YDGSQGCISA-N
SMILES:C(C)(C)(C)[C@@]1(O)[C@@]23[C@@]4([C@](C1)(OC(=O)C4)[H])C(=O)O[C@@]2(OC(=O)[C@@H]3O)[H]
Sinónimos:- (3aS,5aR,8R,8aS,9R,10aS)-9-(1,1-Dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3′,2′:2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione
- (3aS,5aS,9R,10aS)-9-tert-butyl-8,9-dihydroxydihydro-9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione
- 4H,5aH,9H-Furo[2,3-b]furo[3′,2′:2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-, (3aS,5aR,8R,8aS,9R,10aS)-
- 4H,5aH,9H-Furo[2,3-b]furo[3′,2′:2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-, [5aR-(3aS*,5aα,8β,8aS*,9α,10aα)]-
- 4H,5aH,9H-Furo[2,3-b]furo[3′,2′:2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione, 9α-tert-butyl-10,10aβ-dihydro-8α,9-dihydroxy-, (-)-
- Bilobalid
- Bilobalide
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Encontrado 12 productos.
(-)-bilobalide
CAS:LactoneFórmula:C15H18O8Pureza:≥ 95.0 % (HPLC)Forma y color:PowderPeso molecular:326.3Bilobalide
CAS:Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.Fórmula:C15H18O8Pureza:98.27% - 99.91%Forma y color:White SolidPeso molecular:326.3(-)-Bilobalide
CAS:(-)-Bilobalide analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C15H18O8Pureza:(HPLC) ≥99%Forma y color:PowderPeso molecular:326.3Bilobalide
CAS:Bilobalide is a sesquiterpene trilactone, which is a secondary metabolite isolated from the leaves of the Ginkgo biloba tree. The source of bilobalide, Ginkgo biloba, is one of the oldest tree species, extensively studied for its wide array of bioactive compounds. Bilobalide exerts its mode of action predominantly through modulation of various neurotransmitter systems and protection against neuronal injury. It has demonstrated the ability to antagonize the GABAA receptor and inhibit excitotoxicity related to excessive glutamate release, thereby providing neuroprotective effects. The uses and applications of bilobalide are primarily centered around its potential therapeutic roles in neurodegenerative conditions. It is notably researched for its efficacy in ameliorating symptoms associated with Alzheimer's disease and other forms of cognitive decline. Additionally, bilobalide has shown prospective benefits in enhancing microcirculation and protecting neuronal cells from oxidative stress-induced damage. The compound continues to be a subject of extensive pharmacological investigations to further elucidate its mechanisms and expand its applications in neurological and potentially other systemic diseases.Fórmula:C15H18O8Pureza:Min. 95%Forma y color:White PowderPeso molecular:326.3 g/molBilobalide
CAS:Fórmula:C15H18O8Pureza:>96.0%(GC)Forma y color:White to Almost white powder to crystalPeso molecular:326.30Bilobalide
CAS:Producto controladoStability Hygroscopic Applications Bilobalide provides protection against learning and memory impairment by reducing free radical injury and inhibiting neuronal apoptosis in the brain cortex and hippocampal CA1 region in induced vascular dementia rats. References Li, W., et. al.: Mol. Med. Reports, 8, 935 (2013)Fórmula:C15H18O8Forma y color:Off WhitePeso molecular:326.30
