CAS 34298-86-7: Rhein 8-O-β-D-glucopiranósido
Descripción:
Rhein 8-O-β-D-glucopiranósido es un compuesto glucósido derivado de la rhein, que es una antraquinona natural encontrada en varias plantas, particularmente en las especies de ruibarbo. Este compuesto presenta un moiety de glucopiranósido, lo que indica que consiste en una molécula de glucosa unida a la estructura de la rhein a través de un enlace glucosídico. Rhein 8-O-β-D-glucopiranósido es conocido por sus potenciales propiedades farmacológicas, incluyendo actividades antiinflamatorias, antioxidantes y anticancerígenas. Es soluble en agua y exhibe estabilidad bajo diversas condiciones de pH, lo que lo hace adecuado para aplicaciones biológicas. La estructura del compuesto contribuye a su bioactividad, ya que la glicosilación puede mejorar la solubilidad y modular la interacción con objetivos biológicos. Además, la investigación sobre sus mecanismos de acción y potencial terapéutico está en curso, destacando su relevancia en la química medicinal y la investigación de productos naturales. En general, Rhein 8-O-β-D-glucopiranósido representa un compuesto significativo de interés en el estudio de sustancias derivadas de plantas y sus beneficios para la salud.
Fórmula:C21H18O11
InChI:InChI=1S/C21H18O11/c22-6-12-16(25)18(27)19(28)21(32-12)31-11-3-1-2-8-14(11)17(26)13-9(15(8)24)4-7(20(29)30)5-10(13)23/h1-5,12,16,18-19,21-23,25,27-28H,6H2,(H,29,30)/t12-,16-,18+,19-,21-/m1/s1
Clave InChI:InChIKey=WYKUTTFFZMQCGO-HTRBZNBPSA-N
SMILES:O(C1=C2C(C(=O)C=3C(C2=O)=C(O)C=C(C(O)=O)C3)=CC=C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Sinónimos:- 2-Anthracenecarboxylic acid, 5-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-
- 2-Anthroic acid, 5-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-
- 2-Anthroicacid, 5-(b-D-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-(8CI)
- 5-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthracenecarboxylic acid
- 8-Glucosidorhein-9-anthrone
- 8-Glucosylrhein
- Glucorein
- Glucorhein
- Glucorhein (7CI)
- Rhein 8-O-glucoside
- Rhein 8-O-β-<span class="text-smallcaps">D</span>-glucopyranoside
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Encontrado 10 productos.
Rhein 8-glucoside
CAS:Natural glycosideFórmula:C21H18O11Pureza:≥ 95.0 % (HPLC)Forma y color:PowderPeso molecular:446.37Rhein 8-Glucoside
CAS:Producto controladoApplications Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (R318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resource: endophytic fungi from medicinal plants. References Wanitschke, Pharmacology, 20, Suppl. 1, 21 (1980); Raimondi, L., et al.: Pharmacol. Res. Commun., 14, 103 (1982); Franchi-Micheli, S., et al.: J. Pharm. Pharmacol., 35, 262 (1983); Li, S. et al.: J. Asian Nat. Prod. Res., 8, 281 (2006); Shi, Y.Q. et al.: Anticancer. Res., 21, 2847 (2001);Fórmula:C21H18O11Forma y color:NeatPeso molecular:446.36Rhein 8-Glucoside
CAS:Rhein 8-Glucoside (Rhein-8-glucoside) has low laxative activity.Fórmula:C21H18O11Pureza:96.11% - 99.71%Forma y color:SolidPeso molecular:446.36Rhein-8-glucoside
CAS:Rhein-8-glucoside is a naturally occurring anthraquinone glycoside, which is derived primarily from the roots of plants such as Rheum species. These plants have been traditionally used in herbal medicine, and the glycoside form of Rhein enhances its solubility and bioavailability. The mode of action of Rhein-8-glucoside involves the modulation of various cellular pathways, including the inhibition of specific enzymes and the interaction with cellular receptors, potentially leading to anti-inflammatory, antioxidant, and antimicrobial effects. The uses and applications of Rhein-8-glucoside are predominantly in scientific research, where it is utilized to explore its pharmacological potential and understand its role in various biological processes. Researchers investigate its efficacy and mechanisms in the context of disease models, aiming to discover new therapeutic insights or adjunctive treatment strategies. Its study is particularly relevant in the fields of pharmacology and medicinal chemistry, where scientists are interested in its molecular interactions and potential health benefits. As research progresses, Rhein-8-glucoside continues to be an intriguing compound for ongoing investigation in natural product chemistry and drug discovery.Fórmula:C21H18O11Pureza:Min. 95%Forma y color:PowderPeso molecular:446.36 g/mol2-Anthracenecarboxylic acid,5-(b-D-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-
CAS:Fórmula:C21H18O11Pureza:98%Forma y color:SolidPeso molecular:446.3610199999999
