CAS 378-44-9: Betametasona
Descripción:
Betametasona es un corticosteroide sintético con propiedades antiinflamatorias e inmunosupresoras, comúnmente utilizado en el tratamiento de diversas condiciones como alergias, trastornos de la piel y enfermedades autoinmunes. Se caracteriza por su potente actividad glucocorticoide, que ayuda a reducir la inflamación y modular la respuesta inmune. Betametasona tiene una fórmula molecular que refleja su estructura esteroidea, que típicamente presenta un núcleo de ciclopentanoperhidrofenantreno, con grupos funcionales específicos que mejoran su actividad biológica. La sustancia se administra a menudo en varias formas, incluyendo cremas tópicas, inyecciones y tabletas orales, dependiendo de la condición que se trate. Su farmacocinética implica una rápida absorción y metabolismo, con una vida media relativamente larga en comparación con otros corticosteroides, lo que permite una dosificación menos frecuente. Sin embargo, el uso prolongado puede llevar a efectos secundarios como supresión adrenal, aumento de peso y mayor susceptibilidad a infecciones. Al igual que con cualquier medicamento, es esencial usar Betametasona bajo supervisión médica para gestionar eficazmente los riesgos y beneficios potenciales.
Fórmula:C22H29FO5
InChI:InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
Clave InChI:InChIKey=UREBDLICKHMUKA-DVTGEIKXSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Sinónimos:- (11Beta,16Alpha)-9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
- (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
- 9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
- 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
- 9-Fluoro-16β-methylprednisolone
- 9A-Fluoro-11B,17A,21-Trihydroxy-16B-Methylpregna-1,4-Diene-3,20-Dione
- 9Alpha-Fluoro-16Beta-Methylprednisolone
- 9α-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
- 9α-Fluoro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione
- 9α-Fluoro-16β-methylprednisolone
- Becort
- Ver más sinónimos
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BETAMETHASONE CRS
CAS:BETAMETHASONE CRSFórmula:C22H29FO5Forma y color:Crystalline Powder. White. Whitish. Powder.Peso molecular:392.4611Betamethasone-d5
CAS:Producto controladoStability Hygroscopic Applications Glucocorticoid. References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),Fórmula:C22H24D5FO5Forma y color:Off-White To Light YellowPeso molecular:397.49Betamethasone (Betamethasone Acetate EP Impurity A, Betamethasone Dipropionate EP Impurity A, Betamethasone Valerate EP Impurity A, Dexamethasone EP Impurity B)
CAS:Fórmula:C22H29FO5Peso molecular:392.47Betamethasone
CAS:Halogenated derivatives of adrenal cortical hormonesFórmula:C22H29FO5Forma y color:White Off-White Crystalline PowderPeso molecular:392.46 g/molBetamethasone - Bio-X ™
CAS:Producto controladoBetamethasone is a potent anti-inflammatory agent that belongs to the group of corticosteroids. It is used in the treatment of a number of inflammatory diseases, such as allergic states, dermatologic disorders and gastrointestinal disorders. This drug binds to glucocorticoid receptors inhibiting inflammatory signals whilst promoting anti-inflammatory signals. Betamethasone is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C22H29FO5Pureza:Min. 95%Forma y color:PowderPeso molecular:392.46 g/mol9a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS:Fórmula:C22H29FO5Pureza:99%Forma y color:SolidPeso molecular:392.4611Betamethasone
CAS:Fórmula:C22H29FO5Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:392.47Betamethasone
CAS:Fórmula:C22H29FO5Pureza:≥ 97.0%Forma y color:White to off-white powderPeso molecular:392.46Betamethasone
CAS:BetamethasoneFórmula:C22H29FO5Pureza:98.8%Forma y color:Off WhitePeso molecular:392.1999Betamethasone
CAS:Producto controladoBetamethasone is a synthetic corticosteroid, which is an analogue of a glucocorticoid sourced from adrenal cortex hormones. Its mode of action involves modulating the immune response by inhibiting the release of substances in the body that cause inflammation. This is achieved through its binding affinity to glucocorticoid receptors, leading to transcriptional changes that suppress pro-inflammatory cytokine production and other mediators of inflammation. The applications of Betamethasone are extensive due to its potent anti-inflammatory and immunosuppressive properties. It is primarily used in the treatment of various inflammatory conditions, including dermatological disorders such as eczema and psoriasis, as well as rheumatologic conditions like rheumatoid arthritis. Additionally, Betamethasone is employed in certain allergic reactions and as a part of the regimen for certain autoimmune diseases. Its versatility in topical, oral, and injectable forms allows for targeted therapeutic strategies tailored to patient-specific needs, particularly where high-potency corticosteroid intervention is warranted to mitigate severe pathological inflammation.Fórmula:C22H29FO5Pureza:Min. 97 Area-%Forma y color:White PowderPeso molecular:392.46 g/molβmethasone, 97%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C22H29FO5Pureza:97%Forma y color:Powder, White to off-whitePeso molecular:392.47Betamethasone-d5 (Betamethasone Acetate EP Impurity A-d5, Betamethasone Dipropionate EP Impurity A-d5, Betamethasone Valerate EP Impurity A-d5, Dexamethasone EP Impurity B-d5)
CAS:Fórmula:C22H24D5FO5Forma y color:White To Off-White SolidPeso molecular:397.50
