CAS 3810-74-0: Sulfato de estreptomicina
Descripción:
Sulfato de estreptomicina es un antibiótico aminoglucósido derivado de la bacteria Streptomyces griseus. Se utiliza principalmente para tratar diversas infecciones bacterianas, particularmente aquellas causadas por Mycobacterium tuberculosis, lo que lo hace significativo en la terapia de la tuberculosis. El compuesto se caracteriza por su capacidad para inhibir la síntesis de proteínas bacterianas al unirse a la subunidad ribosomal 30S, lo que interrumpe el proceso de traducción. Sulfato de estreptomicina es un polvo cristalino blanco a ligeramente amarillo que es soluble en agua, lo que facilita su administración por inyección. Tiene una fórmula molecular que refleja su estructura compleja, incluyendo múltiples grupos amino e hidroxilo. La forma sulfato mejora su solubilidad y estabilidad. Los efectos secundarios comunes incluyen ototoxicidad y nefrotoxicidad, lo que requiere un monitoreo cuidadoso durante el tratamiento. Sulfato de estreptomicina también es notable por su papel en el desarrollo de resistencia a los antibióticos, subrayando la importancia de su uso juicioso en entornos clínicos. En general, sigue siendo un agente crítico en el arsenal contra ciertas infecciones bacterianas, particularmente en el contexto de cepas multirresistentes.
Fórmula:C21H39N7O12H2O4S
InChI:InChI=1S/C21H39N7O12.H2O4S/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;1-5(2,3)4/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);(H2,1,2,3,4)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;/m0./s1
Clave InChI:InChIKey=CFCMMYICHMLDCC-RMIBZTJPSA-N
SMILES:S(=O)(=O)(O)O.O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(C=O)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3
Sinónimos:- 1,1'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (1:1)
- 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (2:3)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N<sup>1</sup>,N<sup>3</sup>-bis(aminoiminomethyl)-, sulfate (2:3)
- Ag Streptomycin
- Agri-Strep
- Agrimycin 17
- Agrimycin sulfate
- Ambistryn
- Ambistryn S
- D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
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FOURTH INTERNATIONAL STANDARD FOR STREPTOMYCIN
CAS:FOURTH INTERNATIONAL STANDARD FOR STREPTOMYCINFórmula:C42H84N14O36S3Peso molecular:1457.384Streptomycin Sulphate (STM)
CAS:Fórmula:(C21H39N7O12)2·3H2SO4Forma y color:White to off - white, Crystalline powder, Clear, Pale yellowPeso molecular:1457.38Streptomycin Sulfate
CAS:Streptomycins and their derivatives; salts thereof, nesFórmula:(C21H39N7O12)2·3(H2SO4)Forma y color:White PowderPeso molecular:1162.53134Streptomycin sulfate
CAS:Streptomycin sulfate (Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.Fórmula:C21H39N7O12H2SO4Pureza:99.39% - 99.86%Forma y color:White To Off-White PowderPeso molecular:728.68Streptomycin sulfate, Cell Culture Reagent
CAS:Inhibits initiation and causes misreading of rRNA in protein synthesis Streptomycin sulfate is used to study the mechanisms of streptomycin resistance. It is used to inhibit bacterial contamination in cell culture applications in association with penicillin. It is an antibiotic drug initially used for tuberculosis treatment. It inhibits protein synthesis by binding to 30S ribosomal subunit, which induces the misreading of the genetic code. It is involved in the initiation of translation of DNA, thereby results in death for a susceptible bacterium. Further, it controls bacterial and fungal diseases of certain fruit, vegetables, seed, ornamental crops and algae in ornamental ponds and aquaria This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C42H84N14O36S3Peso molecular:1457.38Streptomycin sulfate
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C42H84N14O36S3Forma y color:White to off-white, PowderPeso molecular:1457.38Streptomycin Sulfate
CAS:Fórmula:C21H39N7O12H2SO4Pureza:>95.0%(T)(N)Forma y color:White to Light yellow powder to crystalPeso molecular:728.69Streptomycin sulfate
CAS:Inhibitor of protein synthesis; aminoglycosideFórmula:(C21H39N7O12)2•(H2SO4)3Pureza:Min. 720 Iu/MgForma y color:White Off-White PowderPeso molecular:1,457.39 g/molStreptomycin sulfate
CAS:Producto controladoFórmula:C21H39N7O12H2O4SForma y color:NeatPeso molecular:1457.38Streptomycin sulfate salt
CAS:4x25kgFórmula:C21H39N7O12·5H2SO4Pureza:≥ 720IU/mg (dry basis)Forma y color:White to off-white powderPeso molecular:728.69Streptomycin Sulfate [for Protein Research]
CAS:Fórmula:C21H39N7O12H2SO4Pureza:>95.0%(N)Forma y color:White to Light yellow powder to crystalPeso molecular:728.69Streptomycin Sulfate
CAS:Fórmula:C21H39N7O12H2O4SForma y color:White To Off-White SolidPeso molecular:581.58 3/2 98.08Streptomycin sulfate salt, Ph. Eur. grade
CAS:Fórmula:C21H39N7O12·5H2SO4Forma y color:White to off-white powderPeso molecular:728.69Streptomycin sulfate, Antibiotic for Culture Media Use Only
CAS:Streptomycin sulfate is an antibiotic that inhibits the growth of bacteria by binding to the ribosomal subunit and interfering with protein synthesis. It is used in culture media for the production of human antibodies as well as in drug therapy for methicillin-resistant staphylococcus. Streptomycin sulfate has a high specific activity and low sensitivity, but it also has a low solubility in water. The active form of streptomycin sulfate is streptomycin A, which is produced by the addition of a phenyl ring to neomycin sulfate. In plant roots, streptomycin sulfate inhibits cyanogenic glycosides from being hydrolyzed into hydrogen cyanide (HCN) and benzaldehyde.Fórmula:C42H84N14O36S3Peso molecular:1,457.40 g/molRef: 3D-S-8500
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