CAS 38243-03-7: R-Ginsenoside Rg3
Descripción:
R-Ginsenoside Rg3 es un compuesto natural derivado del ginseng, específicamente un tipo de ginsenosido, que son saponinas esteroides conocidas por sus diversas propiedades farmacológicas. Se caracteriza por su fórmula molecular, que refleja su estructura compleja, presentando típicamente un esqueleto esteroide con moieties de azúcar. Rg3 existe en dos formas estereoisoméricas, siendo la forma R biológicamente activa. Este compuesto es reconocido por sus potenciales beneficios para la salud, incluyendo efectos anticancerígenos, antiinflamatorios y neuroprotectores. Rg3 ha sido estudiado por su capacidad para modular diversas vías biológicas, incluyendo la apoptosis y la proliferación celular, lo que lo hace de interés tanto en la medicina tradicional como en la farmacología moderna. Además, a menudo se explora en el contexto de mejorar la función inmunológica y la vitalidad general. Su solubilidad y estabilidad pueden variar según la formulación y las condiciones, que son consideraciones importantes para su aplicación en suplementos dietéticos y agentes terapéuticos. En general, R-Ginsenoside Rg3 representa un área significativa de investigación en la química de productos naturales y aplicaciones medicinales.
Fórmula:C42H72O13
InChI:InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,51)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-37-35(33(49)31(47)25(20-44)53-37)55-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42+/m0/s1
Clave InChI:InChIKey=RWXIFXNRCLMQCD-CZIWJLDFSA-N
SMILES:C[C@]12[C@@]3(C)[C@@]([C@@]([C@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]5[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@@H](CO)O5)CC4)[H])[H])[H]
Sinónimos:- (20S)-Propanaxadiol
- (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxa
- (3Beta,12Beta)-12,20-Dihydroxydammar-24-En-3-Yl 2-O-Beta-D-Glucopyranosyl-Beta-D-Glucopyranoside
- (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
- (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranoside
- (5xi,8xi,9xi,12alpha,14beta,20R)-12,20-dihydroxylanost-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
- (8xi,9xi,12alpha,14beta,17alpha)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,14-tetramethylgonan-3-yl 2-O-[3-deoxy-3-(hydroxymethyl)-beta-D-glucopyranosyl]-beta-D-glucopyranoside
- 20(R)-Ginsenoside Rg<sub>3</sub>
- 20(R)-Propanaxadiol
- 20(S)-Ginsenoside-Rg3
- 20R-Ginsenoside Rg3
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Encontrado 9 productos.
20(R)-Ginsenoside Rg3-d6
CAS:Producto controladoFórmula:C42D6H66O13Forma y color:NeatPeso molecular:791.0520(R)-Ginsenoside Rg3
CAS:Producto controladoApplications 20(R)-Ginsenoside Rg3 causes an inhibition of phosphatidylinositol 3-kinase/Akt activation that, in turn, results in modulations in Bcl-2 family proteins in such a way that the apoptosis of U87 cells are regulated. Elicits a significant inhibition of in vitro cell adhesion and invasion of U87 cells. in vitro stereoselective inhibition of ginsenosides toward UDP-glucuronosyltransferase isoforms and in vivo inhibition of tumor angiogenesis of lung cancer. References Liu, Y., et al.: Chengdu Yixueyuan Xuebao, 9, 4 (2014); Liu, Y., et al.: Linchuang Junyi Zazhi, 42, 1138 (2014), Kim, D., et al.: Toxicol. Lett., 259, 1 92016); Geng, L., et al.: Zhonghua Zhongyiyao Zazhi, 29, 601 (2014)Fórmula:C42H72O13Forma y color:NeatPeso molecular:785.01(20R)-Ginsenoside Rg3
CAS:(20R)-Ginsenoside Rg3 is a triterpenoid saponin, which is a bioactive compound isolated from the root of Panax ginseng. This product is an integral part of traditional medicine and is now being extensively studied in modern pharmacological research. As a ginsenoside, Rg3 exerts its effects primarily by modulating cellular pathways, inhibiting angiogenesis, and inducing apoptosis in cancer cells. The compound's mode of action involves the downregulation of PI3K/Akt pathways and the inhibition of NF-kB signaling, which are crucial in controlling cell proliferation and survival. Additionally, (20R)-Ginsenoside Rg3 has shown capabilities in preventing metastasis and enhancing the efficacy of traditional chemotherapy agents, thereby providing a promising adjuvant treatment. Its applications are broad, with ongoing research into its potential efficacy against various cancers, including lung, breast, colon, and liver cancers. Beyond oncology, (20R)-Ginsenoside Rg3 is being studied for its neuroprotective, anti-inflammatory, and anti-fatigue properties, offering potential benefits in other chronic diseases.Fórmula:C42H72O13Pureza:Min. 95%Forma y color:PowderPeso molecular:785.01 g/mol20(R)-Ginsenoside Rg3
CAS:20(R)-Ginsenoside Rg3 has shown multiple pharmacological activities and been considered as one of the most promising approaches for fatigue treatment, however, 20(R)-Ginsenoside Rg3 has a low bioavailability after oral administration in human, so, 20(R)-Rg3 can be by intranasal administration, the mechanism was related to the increase of the storage of hepatic glycogen, and the decrease of the accumulation of metabolite such as lactic acid and serum urea nitrogen.Fórmula:C42H72O13Pureza:95%~99%Forma y color:White powderPeso molecular:785.025(20R)-Ginsenoside Rg3
CAS:(20R)-Ginsenoside Rg3 (20(R)-Propanaxadiol) is a compound with anti-aging and antifatigue activities.Fórmula:C42H72O13Pureza:97.03% - 99.67%Forma y color:SolidPeso molecular:785.0120(R)-Ginsenoside Rg3
CAS:Fórmula:C42H72O13Pureza:>97.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:785.03
