CAS 4146-30-9: Sulfato de neomicina B
Descripción:
Sulfato de neomicina B es un antibiótico aminoglucósido derivado de la bacteria *Streptomyces fradiae*. Se utiliza principalmente por sus propiedades antibacterianas, particularmente contra bacterias Gram-negativas. La sustancia se caracteriza por su estructura compleja, que incluye múltiples azúcares amino vinculados a un anillo de aminociclitol central. Sulfato de neomicina B es altamente soluble en agua, lo que lo hace adecuado para diversas formulaciones farmacéuticas, incluidas aplicaciones tópicas y oftálmicas. Presenta un amplio espectro de actividad, siendo particularmente efectivo contra infecciones causadas por *Escherichia coli* y *Klebsiella pneumoniae*. Sin embargo, su uso a menudo está limitado debido a la posible nefrotoxicidad y ototoxicidad, especialmente con la administración sistémica. Sulfato de neomicina B también se utiliza en entornos de laboratorio para la inhibición selectiva del crecimiento bacteriano. Su mecanismo de acción implica la unión al ribosoma bacteriano, interrumpiendo la síntesis de proteínas, lo que finalmente conduce a la muerte celular. Al igual que con todos los antibióticos, el uso apropiado es crucial para mitigar el riesgo de desarrollar resistencia a los antibióticos.
Fórmula:C23H46N6O13·3H2O4S
InChI:InChI=1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1
Clave InChI:InChIKey=OIXVKQDWLFHVGR-WQDIDPJDSA-N
SMILES:S(=O)(=O)(O)O.O([C@H]1[C@H](O[C@H]2[C@H](O)[C@H](O[C@H]3O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H](CO)O2)[C@@H](O)[C@H](N)C[C@@H]1N)[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N
Sinónimos:- (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-D-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside sulfate (salt)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-O-β-<smallcap>D</smallcap>-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:3)
- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-O-β-<smallcap>D</smallcap>-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:3) (salt)
- Neomycin B sulfate
- Neomycin B trisulfate
- Neomycin B, sulfate (1:3) (salt)
- D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:3)
- D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:3) (salt)
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Encontrado 11 productos.
Framycetin sulphate
CAS:Framycetin sulphate is a broad-spectrum antibiotic that is used to treat microbial infections. It has been shown to be effective against many gram-positive and gram-negative bacteria, including methicillin resistant Staphylococcus aureus. Framycetin sulphate prevents bacterial growth by inhibiting protein synthesis through binding to the 30S ribosomal subunit. This binding inhibits the incorporation of amino acids into proteins, thereby preventing the production of new proteins required for cell division and growth. Framycetin sulphate also has preservative properties, which may be due to its ability to chelate metal ions such as copper and iron. Framycetin sulphate can be administered orally or topically in vivo model studies. The drug was not found to have any significant toxic effects on the liver or kidneys in vivo model studies at concentrations up to 40%.Fórmula:C23H52N6O25S3Pureza:Min. 95%Peso molecular:908.88 g/molFramycetin sulfate
CAS:Fórmula:C23H46N6O13·3H2SO4·xH2OPureza:≥ 600IU/mg (dried basis)Forma y color:White to pale yellow powderPeso molecular:712.72 (anhydrous)Neomycin B Trisulfate (Framycetin Trisulfate)
CAS:Fórmula:C23H46N6O13·3H2SO4Forma y color:Off-White SolidPeso molecular:614.66 3*98.08Ref: 4Z-N-080009
1g8.369,00€5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultarD-STREPTAMINE, O-2,6-DIAMINO-2,6-DIDEOXY-β-L-IDOPYRANOSYL-(1->3)-O-β-D-RIBOFURANOSYL-(1->5)-O-[2,6-DIAMINO-2,6-DIDEOXY-A-D-GLUCOPYRANOSYL-(1->4)]-2-DEOXY-, SULFATE (1:3)
CAS:Fórmula:C23H52N6O25S3Pureza:97%Forma y color:SolidPeso molecular:908.8792Framycetin sulfate, BP, Ph. Eur. grade
CAS:Fórmula:C23H46N6O13·3H2SO4·xH2OPureza:≤ 3.0%Forma y color:White or pale yellow crystalline powderPeso molecular:712.72 (anhydrous)Framycetin sulfate
CAS:Framycetin sulfate (Neomycin Sulphate B) belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds.Fórmula:C23H48N6O17SPureza:99.79% - 99.89%Forma y color:White To Yellowish PowderPeso molecular:712.22Framycetin sulfate
CAS:Framycetin sulfate is an antimicrobial agent that belongs to the group of sulfonamides. It is not absorbed from the gastrointestinal tract and acts by inhibiting microbial enzyme systems, such as glutamate dehydrogenase. Framycetin sulfate has been used in the treatment of subclinical mastitis, trichomoniasis, and other infectious diseases. Framycetin sulfate is also used as a pharmaceutical ingredient in medicines for metabolic disorders and other conditions.Fórmula:C23H46N6O13•(H2SO4)3Pureza:Min. 95%Peso molecular:908.88 g/mol
