CAS 478-01-3: Nobiletina
Descripción:
Nobiletina es un flavonoide que se encuentra de forma natural, principalmente en frutas cítricas, particularmente en las cáscaras de naranjas y mandarinas. Pertenece a la clase de compuestos conocidos como polimetoxiflavonas, caracterizados por múltiples grupos metoxi unidos a la estructura básica del flavonoide. Nobiletina exhibe una variedad de actividades biológicas, incluyendo propiedades antioxidantes, antiinflamatorias y potenciales anticancerígenas, lo que lo convierte en un tema de interés en la investigación nutricional y farmacéutica. Su estructura química contribuye a su capacidad para modular diversas vías de señalización, lo que puede tener implicaciones para los beneficios para la salud, particularmente en enfermedades metabólicas y cardiovasculares. Nobiletina también se destaca por su baja solubilidad en agua, lo que puede afectar su biodisponibilidad y absorción en el cuerpo humano. Como suplemento dietético, a menudo se estudia por sus posibles efectos protectores contra el estrés oxidativo y su papel en la promoción de la salud en general. Sin embargo, se necesita más investigación para comprender completamente sus mecanismos de acción y su potencial terapéutico.
Fórmula:C21H22O8
InChI:InChI=1S/C21H22O8/c1-23-13-8-7-11(9-15(13)24-2)14-10-12(22)16-17(25-3)19(26-4)21(28-6)20(27-5)18(16)29-14/h7-10H,1-6H3
Clave InChI:InChIKey=MRIAQLRQZPPODS-UHFFFAOYSA-N
SMILES:O(C)C1=C2C(=C(OC)C(OC)=C1OC)OC(=CC2=O)C3=CC(OC)=C(OC)C=C3
Sinónimos:- 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one
- 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one
- 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one
- 3′,4′,5,6,7,8-Hexamethoxyflavone
- 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-
- 5,6,7,8,3′,4′-Hexamethoxyflavone
- Ccris 9012
- Flavone, 3′,4′,5,6,7,8-hexamethoxy-
- Hexamethoxyflavone
- NSC 618903
- Nsc 76751
- Ver más sinónimos
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Encontrado 14 productos.
Nobiletin
CAS:Producto controladoStability Light Sensitive Applications Nobiletin is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. It is a potent antioxidant with good bioavailability. Nobiletin directly inhibits the ATP-binding cassette proteins P-glycoprotein and breast cancer resistance protein. References Shen, C., et al.: J. Nutr. Biochem. 23, 1367 (2012); Pick, A., et al.: Bioorg. Med. Chem., 19, 2090 (2011); Wang, E., et al.: Chem. Res. Toxicol., 14, 1596 (2001)Fórmula:C21H22O8Forma y color:NeatPeso molecular:402.39Nobiletin
CAS:Nobiletin, a citrus flavonoid isolated from citrus peels like in tangerine, which has anti-inflammatory and anti-tumor activities, it could be a potential protective agent for the prevention and treatment of restenosis after angioplasty. Nobiletin downregulated the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX-2), suppressed cell viability through AKT pathways.Fórmula:C21H22O8Pureza:95%~99%Peso molecular:402.399Nobiletin, 98%
CAS:Fórmula:C21H22O8Pureza:≥ 98.0%Forma y color:White, off-white or light-yellow powderPeso molecular:402.39Nobiletin (2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one)
CAS:Aromatic pesticides with oxygen heteroFórmula:C21H22O8Forma y color:PowderPeso molecular:402.13147Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Fórmula:C21H22O8Pureza:98.78% - 99.76%Forma y color:SolidPeso molecular:402.39Ref: TM-T2834
5mg57,00€10mg88,00€25mg124,00€50mg168,00€100mg265,00€200mg393,00€500mg653,00€1mL*10mM (DMSO)59,00€Nobiletin
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C21H22O8Forma y color:White to light yellow, PowderPeso molecular:402.40Nobiletin
CAS:Oxygen-heterocyclic compoundFórmula:C21H22O8Pureza:≥ 98.0 % (HPLC)Forma y color:PowderPeso molecular:402.4Nobiletin, 95%
CAS:Fórmula:C21H22O8Pureza:≥ 95.0% (dried basis)Forma y color:White, off-white or light-yellow powderPeso molecular:402.39Nobiletin
CAS:Fórmula:C21H22O8Pureza:>95.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:402.40Nobiletin
CAS:Nobiletin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C21H22O8Pureza:(HPLC) ≥99%Forma y color:PowderPeso molecular:402.43',4',5,6,7,8-Hexamethoxyflavone
CAS:3',4',5,6,7,8-Hexamethoxyflavone is a polymethoxylated flavone, which is a type of specialized chemical compound known as a flavonoid. It naturally occurs in certain plants, particularly those within the citrus family, serving as a secondary metabolite. Polymethoxylated flavones like this one are of interest due to their potential interaction with various biological pathways. The mode of action of 3',4',5,6,7,8-Hexamethoxyflavone is linked to its ability to modulate enzyme activity and receptor signaling. It may exhibit antioxidant properties, potentially inhibiting oxidative stress, and has been studied for its role in modulating inflammatory pathways. These actions suggest a potential for influencing physiological responses at the cellular level. This compound has been explored for a range of applications in scientific research, particularly in the fields of pharmacology and biochemistry. Researchers study its effects on cellular models to understand its potential therapeutic roles. Due to its bioactive properties, it may be valuable in investigating treatments for conditions associated with oxidative stress and inflammation. Through a deeper understanding of its mechanisms, 3',4',5,6,7,8-Hexamethoxyflavone could contribute to the development of novel therapeutic strategies.Fórmula:C21H22O8Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:402.39 g/mol
