CAS 50-03-3: Acetato de hidrocortisona
Descripción:
Acetato de hidrocortisona, con el número CAS 50-03-3, es un corticosteroide sintético que se utiliza comúnmente por sus propiedades antiinflamatorias e inmunosupresoras. Es un polvo cristalino blanco a casi blanco que es prácticamente insoluble en agua pero soluble en disolventes orgánicos como el etanol y la acetona. La sustancia se utiliza a menudo en formulaciones tópicas, como cremas y ungüentos, para tratar diversas afecciones cutáneas, incluyendo eczema y dermatitis, así como en formas inyectables para efectos sistémicos. Acetato de hidrocortisona funciona imitando los efectos del cortisol, una hormona natural producida por las glándulas suprarrenales, reduciendo así la inflamación y suprimiendo la respuesta inmune. Sus efectos farmacológicos incluyen vasoconstricción, inhibición de la infiltración de leucocitos y supresión de la producción de citoquinas. Aunque generalmente es bien tolerado, los efectos secundarios potenciales pueden incluir adelgazamiento de la piel, irritación local y efectos sistémicos con el uso prolongado. La dosificación y administración adecuadas son cruciales para minimizar los efectos adversos y maximizar los beneficios terapéuticos.
Fórmula:C23H32O6
InChI:InChI=1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
Clave InChI:InChIKey=ALEXXDVDDISNDU-JZYPGELDSA-N
SMILES:C[C@@]12[C@]([C@]3([C@]([C@@H](O)C1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(CC[C@@]2(C(COC(C)=O)=O)O)[H]
Sinónimos:- (11β)-21-(Acetyloxy)-11,17-dihydroxypregn-4-ene-3,20-dione
- 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-acetate
- 17-Hydroxycorticosterone 21-acetate
- 17α-Hydroxycorticosterone acetate
- 21-Acetate d'hydrocortisone
- 21-Acetato De Hidrocortisona
- 21-Acetoxy-11β,17-dihydroxypregn-4-en-3,20-dione
- 21-Acetoxy-11β,17-dihydroxypregn-4-ene-3,20-dione
- 21-Acetoxy-11β,17α-dihydroxypregn-4-ene-3,20-dione
- 4-Pregnene-11β,17,21-triol-3,20-dione 21-acetate
- Abbocort
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HYDROCORTISONE ACETATE CRS
CAS:HYDROCORTISONE ACETATE CRSFórmula:C23H32O6Forma y color:PowderPeso molecular:404.4966HYDROCORTISONE ACETATE RS
CAS:HYDROCORTISONE ACETATE RSFórmula:C23H32O6Forma y color:PowderPeso molecular:404.4966Hydrocortisone acetate for peak identification CRS
CAS:Hydrocortisone acetate for peak identification CRSFórmula:C23H32O6Forma y color:PowderPeso molecular:404.4966GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
CAS:Producto controlado- 105102-22-5
- 1177-87-3
- 124-94-7
- 13609-67-1
- 14484-47-0
- 1524-88-5
- 2135-17-3
- 2152-44-5
- 25122-46-7
- 25122-57-0
- 3093-35-4
- 33564-31-7
- 356-12-7
- 378-44-9
- 3801-06-7
- 3870-07-3
- 426-13-1
- 4419-39-0
- 50-02-2
- 50-03-3
- 50-04-4
- 50-23-7
- 50-24-8
- 51022-69-6
- 51333-22-3
- 514-36-3
- 53-06-5
- 53-36-1
- 5534-09-8
- 5593-20-4
- 57524-89-7
- 66734-13-2
- 67-78-7
- 73771-04-7
- 76-25-5
- 80474-14-2
- 83-43-2
- 987-24-6
Forma y color:MixtureHydrocortisone acetate
CAS:Producto controladoHydrocortisone acetate is a synthetic corticosteroid, which is a product derived from the modification of natural adrenal cortex hormones. It functions as an anti-inflammatory and immunosuppressive agent through its interaction with glucocorticoid receptors, leading to the modulation of gene expression involved in immune and inflammatory responses. This interaction inhibits the release of pro-inflammatory mediators and reduces the permeability of capillaries, thereby diminishing inflammation and immune activity. Hydrocortisone acetate is extensively used in medical settings to manage conditions requiring suppression of inflammatory and immune responses. It is applied in the treatment of various dermatological conditions, including eczema and psoriasis, as well as allergic reactions. Additionally, it serves as a therapeutic agent in the management of adrenal insufficiency and as an adjunct treatment for other inflammatory disorders. Its pharmacological efficacy and mechanism of action render it an essential component in the arsenal of therapeutic agents targeting inflammatory and autoimmune diseases.Fórmula:C23H32O6Pureza:Min. 97 Area-%Forma y color:PowderPeso molecular:404.5 g/molHydrocortisone acetate
CAS:Hydrocortisone acetateFórmula:C23H32O6Pureza:98.8%Forma y color:White To Off-WhitePeso molecular:404.21989Hydrocortisone 21-Acetate
CAS:Producto controladoImpurity Hydrocortisone EP Impurity C Applications Hydrocortisone 21-Acetate (Hydrocortisone EP Impurity C) is a glucocorticoid. References Middleton, B., et al.: J. Biol. Chem., 256, 4827 (1981), Moore, A., et al.: Ann. Clin. Biochem., 22, 435 (1985)Fórmula:C23H32O6Forma y color:NeatPeso molecular:404.50Hydrocortisone acetate
CAS:Pureza:95.0%Forma y color:Solid, White powderPeso molecular:404.50299072265625Hydrocortisone Acetate
CAS:Fórmula:C23H32O6Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:404.50Hydrocortisone acetate
CAS:Fórmula:C23H32O6Pureza:≤ 1.0%Forma y color:White to almost white crystalline powderPeso molecular:404.51Hydrocortisone acetate
CAS:Producto controladoFórmula:C23H32O6Forma y color:NeatPeso molecular:404.50Hydrocortisone acetate, 97+%
CAS:Hydrocortisone acetate is used to treat hemorrhoids and itching/swelling in the rectum and anus. It is used to treat certain intestinal problems (such as ulcerative colitis of the rectum and other rectal/anal inflammatory conditions). This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C23H32O6Pureza:97+%Forma y color:White to cream, Powder or crystals or crystalline powderPeso molecular:404.51
