
CAS 50-55-5: (-)-Reserpina
Descripción:
(-)-Reserpina es un alcaloide indólico derivado de la planta Rauwolfia serpentina, conocido comúnmente por su uso en la medicina tradicional y como agente antihipertensivo. Se caracteriza por su estructura compleja, que incluye un núcleo tetracíclico y un grupo metoxi. El compuesto exhibe un centro quiral, lo que resulta en su designación como "(-)-Reserpina," indicando su forma enantiomérica específica. (-)-Reserpina funciona principalmente como un antagonista de monoaminas, influyendo en los niveles de neurotransmisores en el cerebro, particularmente al inhibir la captación de norepinefrina y serotonina. Este mecanismo contribuye a sus efectos sedantes y antihipertensivos. La sustancia se administra típicamente en su forma de sal, como el clorhidrato de reserpina, y es conocida por su vida media relativamente larga. Además de sus aplicaciones terapéuticas, se ha estudiado (-)-Reserpina por sus posibles efectos en trastornos de salud mental, aunque su uso ha disminuido debido al desarrollo de medicamentos más nuevos con menos efectos secundarios. Las consideraciones de seguridad incluyen posibles efectos adversos como sedación, trastornos gastrointestinales e impactos cardiovasculares.
Fórmula:C33H40N2O9
InChI:InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
Clave InChI:InChIKey=QEVHRUUCFGRFIF-MDEJGZGSSA-N
SMILES:C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC(OC)=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC)C(OC)=C6)[C@@H]1OC)[H])[H])[H]
Sinónimos:- (3Beta,16Beta,17Alpha,18Alpha,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
- (3Beta,16Beta,17Alpha,18Beta,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
- 11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
- 3,4,5-Trimethoxybenzoyl methyl reserpate
- 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)
- 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate
- Anquil
- Apoplon
- Banasil
- Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.
- Bioserpine
- Ver más sinónimos
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RESERPINE CRS
CAS:RESERPINE CRSFórmula:C33H40N2O9Forma y color:Crystalline Powder. White. Light Yellow. Small. Crystals. Powder.Peso molecular:608.6787Reserpine
CAS:Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoiFórmula:C33H40N2O9Forma y color:White Pale Yellow Crystalline PowderPeso molecular:608.27338Reserpine
CAS:Fórmula:C33H40N2O9Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:608.69Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Fórmula:C33H40N2O9Pureza:98.85% - 99.81%Forma y color:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Peso molecular:608.68Reserpine
CAS:VMAT monoamine transporter inhibitor; anti-hypertensive; anti-psychoticFórmula:C33H40N2O9Pureza:Min. 95%Forma y color:White PowderPeso molecular:608.68 g/molReserpine, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C33H40N2O9Pureza:98%Forma y color:White to yellow-brown, Crystalline powderPeso molecular:608.69Yohimban-16-carboxylic acid,11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester,(3b,16b,17a,18b,20a)-
CAS:Fórmula:C33H40N2O9Pureza:98%Forma y color:SolidPeso molecular:608.6787Reserpine
CAS:Natural alkaloidFórmula:C33H40N2O9Pureza:≥ 95.0 % (HPLC)Forma y color:PowderPeso molecular:608.69Reserpine
CAS:Fórmula:C33H40N2O9Pureza:≥ 98.0%Forma y color:White to pale yellow or faint brown powderPeso molecular:608.69Reserpine
CAS:Producto controladoApplications An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive. References Muller, J.M., et al.: Experientia, 8, 338 (1952), Schirmer, R.E., et al.: Anal. Profiles Drug Subs., 4, 384 (1975), Diener, R.M., et al.: Toxicol. Pathol., 8, 1 (1980),Fórmula:C33H40N2O9Forma y color:Off-WhitePeso molecular:608.68Reserpine, 99%
CAS:Inhibits vesicular uptake of catecholamines and serotoninReserpine is an antipsychotic and antihypertensive drug used to treat the hypertension, strokes, heart attacks and kidney problems. It is used to treat the symptoms of dyskinesia in patients who are affected by huntington’s disease. It is widely used as a reference material in the mass spectroscopy technique and also used as a sedative for horses. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C33H40N2O9Pureza:99%Forma y color:White to cream to yellow, PowderPeso molecular:608.69Reserpine extrapure, 99%
CAS:Fórmula:C33H40N2O9Pureza:min. 99%Forma y color:White to pale yellow to pale beige to pale brown, Crystalline powder, ClearPeso molecular:608.69