CAS 500-38-9: Ácido nordihidroguaiarético
Descripción:
Ácido nordihidroguaiarético (NDGA) es un compuesto fenólico que se encuentra de forma natural, derivado principalmente del arbusto de creosota (Larrea tridentata). Se caracteriza por sus propiedades antioxidantes, que se atribuyen a su capacidad para eliminar radicales libres e inhibir la peroxidación lipídica. NDGA tiene una fórmula molecular de C15H14O4 y presenta una estructura compleja que incluye dos grupos metoxi y un moiety de catecol. Este compuesto ha sido estudiado por sus posibles aplicaciones terapéuticas, incluyendo efectos antiinflamatorios y anticancerígenos, aunque su uso es limitado debido a la toxicidad potencial y los efectos secundarios. NDGA también es conocido por exhibir propiedades antimicrobianas y se ha investigado por su papel en la conservación de alimentos. En términos de solubilidad, es moderadamente soluble en disolventes orgánicos, pero menos en agua. Debido a su estructura química única y actividad biológica, NDGA sigue siendo de interés tanto en la investigación farmacológica como en aplicaciones industriales. Sin embargo, las consideraciones de seguridad y regulación son esenciales al manipular este compuesto.
Fórmula:C18H22O4
InChI:InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
Clave InChI:InChIKey=HCZKYJDFEPMADG-UHFFFAOYSA-N
SMILES:C(C(C(CC1=CC(O)=C(O)C=C1)C)C)C2=CC(O)=C(O)C=C2
Sinónimos:- 1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane
- 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis(pyrocatechol)
- 4,4'-(2,3-Dimethyltetramethylen)dibrenzcatechin
- 4,4'-(2,3-Dimethyltetramethylene)Dipyrocatechol
- 4,4'-(2,3-Dimetiltetrametilen)Dipirocatecol
- 4,4′-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol]
- 4-[4-(3,4-Dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
- Butane, 1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethyl-
- Dihydronorguaiaretic acid
- Dinorguaiaretic acid, dihydro-
- Ndga
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Encontrado 16 productos.
Nordihydroguaiaretic acid, 97%
CAS:Nordihydroguaiaretic acid is used in the treatment of multiple diseases, including cardiovascular diseases, neurological disorders and cancers. It is also used as an antioxidant. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C18H22O4Pureza:97%Forma y color:Crystals or powder or crystalline powder, White to cream to pale brown to pale yellowPeso molecular:302.37Nordihydroguaiaretic acid
CAS:PolyphenolFórmula:C18H22O4Pureza:≥ 98.0 % (HPLC)Forma y color:PowderPeso molecular:302.37Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid is a lignan-type compound, which is a naturally occurring product primarily sourced from the resin of the creosote bush, *Larrea tridentata*. It functions as a powerful antioxidant through the inhibition of lipid peroxidation and scavenging of free radicals, thereby preventing oxidative stress in biological systems. Due to its antioxidant properties, Nordihydroguaiaretic acid is extensively used in scientific research to study oxidative stress mechanisms and its implications in various pathological conditions, including cancer, aging, and neurodegenerative diseases. Additionally, it serves as a reference compound in studies exploring the development of novel antioxidants. Its role in inhibiting key metabolic pathways also makes it a valuable tool in biochemical assays aimed at investigating the modulation of enzymatic activities.Fórmula:C18H22O4Peso molecular:302.37 g/molRef: 3D-N-8500
5gA consultar10gA consultar25gA consultar50gA consultar2500mgA consultar-Unit-ggA consultarNordihydroguaiaretic acid
CAS:Fórmula:C18H22O4Pureza:≥ 97.0%Forma y color:White to off-white or faint yellow-beige powder or crystalsPeso molecular:302.37GB 5009.32-2016 Antioxidants Mixture 161 1000 mg/L in Acetonitrile
CAS:Producto controladoForma y color:MixtureNordihydro Guaiaretic Acid (mixture of diastereomers)
CAS:Producto controladoApplications Nordihydro Guaiaretic Acid is a lipoxygenase inhibitor; polyphenol-bearing o-dihydroxy (catechol) structure. Inhibitor of broad bean lipoxygenase. The oxidation product from Resveratrol (R150000) showed a high inhibitory activity, whereas Resveratrol itself had no activity and its oxidation efficiency was low. References Brash, A., et al.: J. Biol. Chem., 274, 23679 (1999), Fujimoto, A., et al.: Bioorg. Med. Chem. Lett., 20, 7393 (2010), Ridolfi, M., et al.: J. Agric. Food Chem., 50, 835 (2002),Fórmula:C18H22O4Forma y color:White To BrownPeso molecular:302.36Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Fórmula:C18H22O4Pureza:97.82% - 99.91%Forma y color:SolidPeso molecular:302.36Nordihydroguaiaretic acid - mixture of diastereomers
CAS:Nordihydroguaiaretic acid - mixture of diastereomers is a potent antioxidant compound, regarded as a lignan. This compound is primarily sourced from the creosote bush, known scientifically as *Larrea tridentata*. The mode of action of nordihydroguaiaretic acid involves its ability to scavenge free radicals, effectively neutralizing them and thus protecting cellular components from oxidative damage. In scientific research, nordihydroguaiaretic acid is extensively utilized due to its significant antioxidative properties. It is commonly employed in studies investigating oxidative stress-related damage and its implications in various biological processes and diseases. Additionally, its role in inhibiting lipoxygenase, a key enzyme in inflammatory pathways, expands its application in experimental models studying inflammation and related disorders. Researchers also explore its potential in extending the shelf life of various biological materials by preventing oxidation. These applications underscore the compound's value in experimental and potentially translational research.Fórmula:C18H22O4Forma y color:PowderPeso molecular:302.36 g/molNordihydroguaiaretic Acid
CAS:Fórmula:C18H22O4Pureza:>97.0%(HPLC)Forma y color:White to Orange to Green powder to crystalPeso molecular:302.37Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Fórmula:C18H22O4Pureza:(HPLC) ≥95%Forma y color:PowderPeso molecular:302.38Nordihydroguaiaretic acid, 95%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C18H22O4Pureza:95%Forma y color:White to light yellow to light beige, PowderPeso molecular:302.37
