CAS 52-67-5: (-)-Penicilamina
Descripción:
(-)-Penicilamina es un agente quelante y un derivado de la penicilina, utilizado principalmente en el tratamiento de condiciones como la artritis reumatoide y la enfermedad de Wilson, donde ayuda a eliminar el exceso de cobre del cuerpo. Es un aminoácido con un grupo tiol, que le permite formar complejos con iones metálicos, mejorando sus efectos terapéuticos. La sustancia se caracteriza por su naturaleza quiral, existiendo como un solo enantiómero, que es la forma biológicamente activa. (-)-Penicilamina se administra típicamente por vía oral y es conocido por su capacidad para unirse a metales pesados, facilitando su excreción. Tiene una solubilidad relativamente baja en agua y es sensible a la luz y al aire, lo que requiere condiciones de almacenamiento adecuadas. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales y reacciones cutáneas, y su uso requiere monitoreo debido a la posible toxicidad e interacciones con otros medicamentos. En general, (-)-Penicilamina desempeña un papel significativo en el manejo de condiciones médicas específicas a través de sus propiedades químicas únicas.
Fórmula:C5H11NO2S
InChI:InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1
Clave InChI:InChIKey=VVNCNSJFMMFHPL-VKHMYHEASA-N
SMILES:[C@@H](C(C)(C)S)(C(O)=O)N
Sinónimos:- (-)-Penicillamine
- (2S)-2-Azaniumyl-3-methyl-3-sulfanylbutanoate
- (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
- (S)-3,3-Dimethylcysteine
- (S)-Penicillamine
- 2-Amino-3-mercapto-3-methylbutanoic acid
- 3,3-Dimethyl-D-cysteine
- 3-Mercapto-<span class="text-smallcaps">D</span>-valine
- 3-Mercapto-D-valine
- <span class="text-smallcaps">D</span>-(-)-Penicillamine
- <span class="text-smallcaps">D</span>-3-Mercaptovaline
- Ver más sinónimos
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Encontrado 20 productos.
D-Penicillamine
CAS:Fórmula:C5H11NO2SPureza:98.0 - 101.0 % (dried basis)Forma y color:White to off-white powderPeso molecular:149.21D-Penicillamine, USP grade
CAS:Fórmula:C5H11NO2SPureza:97.0 - 102.0 %Forma y color:White to off-white powder or solidPeso molecular:149.21D-Penicillamine-d6 (Racemic)
CAS:Producto controladoFórmula:C5H5D6NO2SForma y color:NeatPeso molecular:155.253-Thio-D-valine
CAS:3-Thio-D-valineFórmula:C5H11NO2SPureza:98+%Forma y color: white solidPeso molecular:149.21g/molPenicillamine
CAS:Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copperFórmula:C5H11NO2SPureza:99.69% - 99.8%Forma y color:Fine White Or Practically White Crystalline Powder SolidPeso molecular:149.21H-D-Pen-OH
CAS:M06142 - H-D-Pen-OHFórmula:C5H11NO2SPureza:95%Forma y color:Solid, White to off-white crystalline powderPeso molecular:149.2100067138672Ref: 10-M06142
1gA consultar5g31,00€25gA consultar100gA consultar500gA consultar100mg80,00€250mgA consultarD(-)-Penicillamine, 99%, specified according to Ph.Eur. and USP
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C5H11NO2SPureza:99%Forma y color:Powder, White to almost whitePeso molecular:149.21D-Penicillamine
CAS:Applications A Penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning. References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010); Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010);Fórmula:C5H11NO2SForma y color:NeatPeso molecular:149.21D-(-)-Penicillamine, 98%
CAS:It is used mainly as chelating agent in heavy metal poisoning as in lead, mercury and copper poisoning. It is used in Wilson's disease. It is used in pharmacy as chelating agent and as immunosuppressant for treating rheumatoid arthritis by reducing the number of T cells, inhibiting the macrophages, by reducing the activity of Interleukin 1 and rheumatoid factor and in preventing crosslinking of the collagen. It acts as an exogenous NOS modulator. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C5H11NO2SPureza:98%Forma y color:Powder, White to pale creamPeso molecular:149.21D-Penicillamine, Ph. Eur. grade
CAS:Fórmula:C5H11NO2SPureza:≤ 0.1%Forma y color:White or almost white crystalline powderPeso molecular:149.21D-Penicillamine
CAS:D-Penicillamine is a nonsteroidal anti-inflammatory drug that is used to treat bowel disease, including ulcerative colitis and Crohn's disease. It has also been used as a treatment for schizophrenia that is unresponsive to other treatments. D-Penicillamine binds covalently to reactive oxygen species (ROS), thereby preventing their interaction with proteins and DNA. The binding of ROS by D-penicillamine can be monitored using electrochemical impedance spectroscopy (EIS). The compound has also been shown to reduce the expression of bcl-2 protein in human cells, which may result in increased oxidative injury and rates of cell proliferation. D-Penicillamine has been shown to have therapeutic benefits for patients with primary sclerosing cholangitis, myocardial infarcts, or preparative high performance liquid chromatography (HPLC) analysis.Fórmula:C5H11NO2SPureza:Min 97%Forma y color:White PowderPeso molecular:149.21 g/molD-Penicillamine
CAS:Fórmula:C5H11NO2SPureza:>98.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:149.21D-Penicillamine - USP
CAS:D-Penicillamine is a drug that is used to treat chronic inflammatory bowel disease and rheumatoid arthritis. The drug binds to the enzyme glutathione reductase, which converts oxidized glutathione back into its reduced form. This reaction prevents the formation of reactive oxygen species, which are harmful to cells. D-penicillamine also inhibits the production of cytokines, such as IL-1β and TNF-α, which are involved in inflammation. D-penicillamine may be used in combination with nonsteroidal anti-inflammatory drugs (NSAIDs) for the treatment of chronic arthritis because it reduces NSAID toxicity by binding to NSAIDs and preventing them from forming toxic metabolites.Fórmula:C5H11NO2SPureza:Min. 95%Peso molecular:149.21 g/molPenicillamine
CAS:Thioglycolic acid and mercaptocarboxylic acidsFórmula:C5H11NO2SForma y color:White Off-White PowderPeso molecular:149.21 g/molD-Penicillamine-d6
CAS:Producto controladoApplications D-Penicillamine-d6 is the isotope labelled analog of D-Penicillamine which is a Penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning. References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010), Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010),Fórmula:C5D6H5NO2SForma y color:NeatPeso molecular:155.248
