CAS 52214-84-3: Ciprofibrato
Descripción:
Ciprofibrato es un compuesto sintético clasificado como un fibrato, utilizado principalmente en el manejo de la dislipidemia, particularmente para reducir los niveles de triglicéridos y aumentar el colesterol de lipoproteínas de alta densidad (HDL). Su estructura química presenta un grupo fenoxi y un moiety de ácido carboxílico, que contribuyen a sus propiedades moduladoras de lípidos. La sustancia es conocida por su capacidad para activar los receptores activados por proliferadores de peroxisomas (PPARs), que juegan un papel crucial en el metabolismo de lípidos. Ciprofibrato se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal. Exhibe una vida media moderada, lo que permite una dosificación una o dos veces al día. El compuesto generalmente es bien tolerado, aunque los efectos secundarios potenciales pueden incluir trastornos gastrointestinales y problemas relacionados con los músculos. Al igual que otros fibratos, es importante monitorear la función hepática y los niveles de enzimas musculares durante el tratamiento. Ciprofibrato se utiliza a menudo en conjunto con modificaciones en el estilo de vida y otros agentes reductores de lípidos para lograr resultados terapéuticos óptimos en pacientes con niveles elevados de lípidos.
Fórmula:C13H14Cl2O3
InChI:InChI=1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)
Clave InChI:InChIKey=KPSRODZRAIWAKH-UHFFFAOYSA-N
SMILES:ClC1(Cl)C(C1)C2=CC=C(OC(C(O)=O)(C)C)C=C2
Sinónimos:- 2-(4-(2,2-Dichlorocyclopropyl)phenoxy)2-methylpropanoic acid
- 2-(p-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropionic acid
- 2-[4-(2,2-Dichloro-cyclopropyl)-phenoxy]-2-methyl-propionic acid
- Brn 1984981
- Ccris 173
- Ciprofibrato
- Ciprofibrato [INN-Spanish]
- Ciprofibratum
- Ciprofibratum [INN-Latin]
- Ciprol
- Lipanor
- Ver más sinónimos
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Encontrado 17 productos.
Ciprofibrate CRS
CAS:Ciprofibrate CRSFórmula:C13H14Cl2O3Forma y color:Crystalline Powder. White. Whitish. Powder.Peso molecular:289.1545Ciprofibrate
CAS:Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.Fórmula:C13H14Cl2O3Pureza:100% - 99.95%Forma y color:White Or Almost White Crystalline PowderPeso molecular:289.15Ciprofibrate
CAS:Fórmula:C13H14Cl2O3Pureza:>98.0%(GC)(T)Forma y color:White to Light yellow powder to crystalPeso molecular:289.15Ciprofibrate
CAS:Producto controladoApplications Ciprofibrate is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic. References Davison, C., et al.: Drug. Metab. Dispos., 3, 520 (1975), Arnold, A., et al.: J. Pharm. Sci., et al.: 68, 1557 (1979), Tuchman-Duplessis, H., et al.: Toxicology, 12, 1 (1979),Fórmula:C13H14Cl2O3Forma y color:WhitePeso molecular:289.15Ciprofibrate - Bio-X ™
CAS:Ciprofibrate is a fibrate drug that is used as a lipid-lowering agent. This drug reduces both LDL and VLDL cholesterol levels in the blood. Ciprofibrate works by reducing the production of triglycerides in the liver and increasing the removal of triglycerides from the blood. This drug is an agonist of peroxisome proliferator-activated receptor alpha. Ciprofibrate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C13H14Cl2O3Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:289.15 g/mol2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
CAS:2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid (CGP) is a drug that blocks the nuclear receptor PPARγ. It has been shown to reduce cholesterol levels by inhibiting the synthesis of cholesterol, as well as reducing liver lesions in vivo. CGP also inhibits the growth of cancer cells through its ability to bind to DNA and regulate transcriptional activity. The response element for this compound is found in the promoter region of the gene encoding the growth factor-β1 (GF-β1), which is an important regulator of cell proliferation, differentiation, and apoptosis. CGP also inhibits peroxisome proliferator activator receptor α (PPARα) and γ (PPARγ). This inhibition leads to decreased expression of genes involved in lipid metabolism, such as acyl CoA synthase and fatty acid synthetase. CGP has also been shown to be carcinogenic in vivoFórmula:C13H14Cl2O3Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:289.15 g/mol2-(4-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid
CAS:Pureza:95.0%Forma y color:Solid, White to slightly pale yellow powderPeso molecular:289.1499938964844Ciprofibrate
CAS:CiprofibrateFórmula:C13H14Cl2O3Pureza:99.9%Forma y color:WhitePeso molecular:288.032Propanoic acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-
CAS:Fórmula:C13H14Cl2O3Pureza:98%Forma y color:SolidPeso molecular:289.15452-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic Acid
CAS:2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic AcidPureza:98%Peso molecular:289.15g/mol
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