CAS 524-12-9: Wedelolactona
Descripción:
Wedelolactona es un compuesto que se encuentra de forma natural clasificado como un derivado de la cumarina, extraído principalmente de varias plantas, incluidas las del género *Wedelia*. Se caracteriza por su estructura aromática, que incluye un grupo funcional lactona, lo que contribuye a sus propiedades químicas distintivas. El compuesto exhibe una variedad de actividades biológicas, incluyendo efectos antiinflamatorios, antioxidantes y potenciales efectos anticancerígenos, lo que lo hace de interés en la investigación farmacológica. Wedelolactona es soluble en disolventes orgánicos pero tiene una solubilidad limitada en agua, lo que influye en su biodisponibilidad y aplicación en química medicinal. Su fórmula molecular es C10H10O3 y tiene un peso molecular relativamente bajo. La estructura del compuesto le permite interactuar con varios objetivos biológicos, y los estudios en curso continúan explorando su potencial terapéutico. Además, debido a su origen natural, Wedelolactona a menudo se investiga por su papel en la medicina tradicional y sus posibles aplicaciones en contextos terapéuticos modernos.
Fórmula:C16H10O7
InChI:InChI=1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
Clave InChI:InChIKey=XQDCKJKKMFWXGB-UHFFFAOYSA-N
SMILES:O=C1C2=C(C=3C(O1)=CC(OC)=CC3O)OC=4C2=CC(O)=C(O)C4
Sinónimos:- 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one
- 1,8,9-Trihydroxy-3-methoxy-[1]benzofuro[3,2-c]chromen-6-one
- 1,8,9-trihydroxy-3-methoxy-6H-[1]benzofuro[3,2-c]chromen-6-one
- 6H-Benzofuro[3,2-c][1]benzopyran-6-one, 1,8,9-trihydroxy-3-methoxy-
- 7-Methoxy-5,11,12-Trihydroxycoumestan
- Wedelolactone
Ordenar por
Encontrado 13 productos.
Wedelolactone
CAS:Wedelolactone is a potent Î2-arrestin-biased G protein-coupled receptor-35 (GPR35) agonist, GPR35 has been shown to be a target of the asthma drugs cromolyn disodium and nedocromil sodium. Wedelolactone has anti-inflammatory, growth inhibitory, anti-cancer, anti-fibrotic, and pro-apoptotic effects. Wedelolactone stimulates ER genomic and non-genomic signalling pathways; it can significantly inhibit the activation of LX-2 cells, the underlying mechanisms of which included inducing Bcl-2 family involved apoptosis, up-regulating phosphorylated status of ERK and JNK expressions, and inhibiting NF-κB mediated activity.Fórmula:C16H10O7Pureza:95%~99%Peso molecular:314.249Wedelolactone
CAS:M06041 - WedelolactoneFórmula:C16H10O7Pureza:>98%Forma y color:SolidPeso molecular:314.2489929199219Ref: 10-M06041
1gA consultar5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultarWedelolactone
CAS:Wedelolactone is a naturally occurring bioactive compound, classified as a coumestan, which is derived from the plant Eclipta alba, commonly referred to as false daisy. This polyphenolic compound exerts its effects through various modes of action, including inhibition of 5-lipoxygenase and modulation of NF-κB signaling pathways. The inhibition of these pathways suggests its potential role in the regulation of inflammation and cell proliferation. The primary uses and applications of Wedelolactone are explored in the context of its anti-inflammatory, hepatoprotective, and anticancer properties. Its ability to modulate molecular pathways linked to inflammation and cell cycle regulation positions it as a compound of significant interest in the development of therapeutic agents for diseases such as cancer, liver disorders, and inflammatory conditions. Research continues to explore its efficacy, molecular interactions, and potential applications in pharmacology, making it a focal point of study in natural product chemistry and medicinal sciences.Fórmula:C16H10O7Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:314.25 g/molWedelolactone
CAS:Fórmula:C16H10O7Pureza:>98.0%(HPLC)Forma y color:White to Dark green powder to crystalPeso molecular:314.25Wedelolactone
CAS:LactoneFórmula:C16H10O7Pureza:≥ 90.0 % (HPLC)Forma y color:PowderPeso molecular:314.25Wedelolactone
CAS:Wedelolactone analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C16H10O7Pureza:(HPLC) ≥99%Forma y color:PowderPeso molecular:314.25Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Fórmula:C16H10O7Pureza:98.07% - 99.76%Forma y color:SolidPeso molecular:314.25Ref: TM-T3384
1mg35,00€5mg74,00€10mg115,00€25mg185,00€50mg331,00€100mg437,00€500mg1.008,00€1mL*10mM (DMSO)52,00€
