CAS 548-73-2: Droperidol
Descripción:
Droperidol es un medicamento antipsicótico y antiemético que se utiliza principalmente en el manejo de náuseas y vómitos, particularmente en entornos quirúrgicos y postoperatorios. Pertenece a la clase de compuestos de butirofenona y actúa como un antagonista de la dopamina, dirigiéndose específicamente a los receptores D2 en el sistema nervioso central. Droperidol se caracteriza por su capacidad para inducir sedación y reducir la ansiedad, lo que lo hace útil en entornos preoperatorios. La sustancia se administra típicamente por inyección y tiene un inicio de acción relativamente rápido. Su estructura química incluye un grupo de butirofenona, que contribuye a sus propiedades farmacológicas. Aunque es efectivo, Droperidol se ha asociado con efectos secundarios potenciales, incluyendo sedación, hipotensión y, en casos raros, efectos cardíacos graves como la prolongación del QT. Debido a estos riesgos, su uso se ha vuelto más cauteloso y a menudo se reserva para escenarios clínicos específicos. En general, Droperidol sigue siendo una herramienta valiosa en la práctica anestésica, equilibrando la eficacia con un cuidadoso monitoreo de la seguridad del paciente.
Fórmula:C22H22FN3O2
InChI:InChI=1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)
Clave InChI:InChIKey=RMEDXOLNCUSCGS-UHFFFAOYSA-N
SMILES:O=C1N(C=2C(N1)=CC=CC2)C=3CCN(CCCC(=O)C4=CC=C(F)C=C4)CC3
Sinónimos:- 1-(1-[4-(p-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone
- 1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone
- 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-2H-benzimidazol-2-one
- 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one
- 1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
- 2-Benzimidazolinone, 1-[1-[3-(p-fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-
- 2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-
- 3-(1-(3-(4-fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-1H-benzimidazol-2-one
- Dehydrobenzperidol
- Dridol
- Droleptan
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Droperidol
CAS:Clozapine; droperidol; and imipramine hydrochloridFórmula:C22H22FN3O2Forma y color:PowderPeso molecular:379.16961Droperidol
CAS:Producto controladoApplications A D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic. Neuroprotective agent. References Yelnosky, J., et al.: Toxicol. Appl. Pharmacol., 6, 37 (1964), Janicki, C.A., et al.: Anal. Profiles Drug Subs., 7, 171 (1978), Hamik, et al.: Cancer Chemother. Pharmacol., 24, 307 (1989), Heyer, E.J., et al.: Brain Res., 863, 20 (2000),Fórmula:C22H22FN3O2Forma y color:NeatPeso molecular:379.43Droperidol
CAS:Fórmula:C22H22FN3O2Pureza:≥ 98.0%Forma y color:White to off-white powderPeso molecular:379.43Droperidol
CAS:Producto controladoDroperidol is a butyrophenone derivative, which is an antipsychotic agent and antiemetic medication, sourced from synthetic chemical processes. Its mode of action involves antagonism of dopamine D2 receptors in the central nervous system, particularly in the chemoreceptor trigger zone of the brain, and it also possesses some alpha-adrenergic blocking properties. Droperidol is primarily used in clinical settings for its sedative and antiemetic effects. It is frequently administered in perioperative and emergency medicine to prevent nausea and vomiting associated with surgical procedures or anesthesia. Additionally, due to its sedative properties, it serves as an adjunct in neuroleptanalgesia, where it is used to achieve a tranquil state during minor surgical procedures. Furthermore, it has been utilized in managing acute agitation in psychiatry and emergency settings. However, its use necessitates caution due to potential side effects, such as QT interval prolongation, which requires careful monitoring of cardiac function.Fórmula:C22H22FN3O2Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:379.43 g/molDroperidol
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C22H22FN3O2Forma y color:White to yellow, PowderPeso molecular:379.44Droperidol
CAS:DroperidolFórmula:C22H22FN3O2Pureza:99.3%Forma y color:White To BeigePeso molecular:379.16961Droperidol
CAS:Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.Fórmula:C22H22FN3O2Pureza:97.16% - 98%Forma y color:SolidPeso molecular:379.43
